FR2476071A1 - Nouveaux acides 2-amino-3-(a-hydroxybenzyl)-phenylacetiques et leurs esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant - Google Patents
Nouveaux acides 2-amino-3-(a-hydroxybenzyl)-phenylacetiques et leurs esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant Download PDFInfo
- Publication number
- FR2476071A1 FR2476071A1 FR8103188A FR8103188A FR2476071A1 FR 2476071 A1 FR2476071 A1 FR 2476071A1 FR 8103188 A FR8103188 A FR 8103188A FR 8103188 A FR8103188 A FR 8103188A FR 2476071 A1 FR2476071 A1 FR 2476071A1
- Authority
- FR
- France
- Prior art keywords
- amino
- lower alkyl
- hydrogen
- hydroxybenzyl
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12254480A | 1980-02-19 | 1980-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2476071A1 true FR2476071A1 (fr) | 1981-08-21 |
FR2476071B1 FR2476071B1 (fi) | 1984-05-11 |
Family
ID=22403319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8103188A Granted FR2476071A1 (fr) | 1980-02-19 | 1981-02-18 | Nouveaux acides 2-amino-3-(a-hydroxybenzyl)-phenylacetiques et leurs esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS56131552A (fi) |
AU (1) | AU538240B2 (fi) |
BE (1) | BE887566A (fi) |
CA (1) | CA1156655A (fi) |
CH (1) | CH648283A5 (fi) |
DE (1) | DE3105285A1 (fi) |
FR (1) | FR2476071A1 (fi) |
GB (1) | GB2071086B (fi) |
IL (1) | IL61945A (fi) |
IT (1) | IT1146744B (fi) |
NL (1) | NL8100808A (fi) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2465710A1 (fr) * | 1979-09-26 | 1981-03-27 | Robins Co Inc A H | Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL64724A0 (en) * | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
AR030346A1 (es) | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico |
AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
AU2002247284A1 (en) | 2001-04-02 | 2002-10-15 | Alcon, Inc. | Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac |
TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
CN102438979A (zh) * | 2009-03-12 | 2012-05-02 | 麦迪凯姆股份公司 | 苯甲酰基苯乙酰胺衍生物的新型晶体 |
EP2389354A1 (en) * | 2009-04-06 | 2011-11-30 | Medichem, S.A. | 2-{2-amino-3-ýhydroxy(phenyl)methyl¨phenyl} acetamide |
CN106631881B (zh) * | 2016-09-08 | 2018-09-21 | 南京工业大学 | 2-(3-苄基-2-(二甲基氨基)苯基)乙酰胺及合成方法和用途 |
CN112794809B (zh) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | 一种高纯度奈帕芬胺中间体的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2366015A1 (fr) * | 1975-11-05 | 1978-04-28 | Robins Co Inc A H | Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation |
BE885393A (fr) * | 1979-09-26 | 1981-01-16 | Robins Co Inc A H | Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH577461A5 (fi) * | 1975-08-13 | 1976-07-15 | Robins Co Inc A H |
-
1981
- 1981-01-20 IL IL61945A patent/IL61945A/xx unknown
- 1981-02-09 IT IT67177/81A patent/IT1146744B/it active
- 1981-02-13 DE DE19813105285 patent/DE3105285A1/de not_active Withdrawn
- 1981-02-16 AU AU67330/81A patent/AU538240B2/en not_active Ceased
- 1981-02-18 CA CA000371185A patent/CA1156655A/en not_active Expired
- 1981-02-18 NL NL8100808A patent/NL8100808A/nl not_active Application Discontinuation
- 1981-02-18 GB GB8105091A patent/GB2071086B/en not_active Expired
- 1981-02-18 BE BE0/203830A patent/BE887566A/fr not_active IP Right Cessation
- 1981-02-18 FR FR8103188A patent/FR2476071A1/fr active Granted
- 1981-02-18 CH CH1076/81A patent/CH648283A5/fr not_active IP Right Cessation
- 1981-02-19 JP JP2363881A patent/JPS56131552A/ja active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2366015A1 (fr) * | 1975-11-05 | 1978-04-28 | Robins Co Inc A H | Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation |
BE885393A (fr) * | 1979-09-26 | 1981-01-16 | Robins Co Inc A H | Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2465710A1 (fr) * | 1979-09-26 | 1981-03-27 | Robins Co Inc A H | Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant |
Also Published As
Publication number | Publication date |
---|---|
IT8167177A0 (it) | 1981-02-09 |
IL61945A0 (en) | 1981-02-27 |
JPS56131552A (en) | 1981-10-15 |
CH648283A5 (fr) | 1985-03-15 |
BE887566A (fr) | 1981-06-15 |
AU538240B2 (en) | 1984-08-02 |
JPH0153266B2 (fi) | 1989-11-13 |
NL8100808A (nl) | 1981-09-16 |
IT1146744B (it) | 1986-11-19 |
DE3105285A1 (de) | 1982-01-21 |
CA1156655A (en) | 1983-11-08 |
GB2071086A (en) | 1981-09-16 |
GB2071086B (en) | 1984-02-08 |
FR2476071B1 (fi) | 1984-05-11 |
IL61945A (en) | 1984-09-30 |
AU6733081A (en) | 1981-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |