BE887566A - Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant - Google Patents

Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant

Info

Publication number
BE887566A
BE887566A BE0/203830A BE203830A BE887566A BE 887566 A BE887566 A BE 887566A BE 0/203830 A BE0/203830 A BE 0/203830A BE 203830 A BE203830 A BE 203830A BE 887566 A BE887566 A BE 887566A
Authority
BE
Belgium
Prior art keywords
phenylacetics
hedroxybenzyl
amides
alpha
esters
Prior art date
Application number
BE0/203830A
Other languages
English (en)
Inventor
W J Welstead
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of BE887566A publication Critical patent/BE887566A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE0/203830A 1980-02-19 1981-02-18 Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant BE887566A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12254480A 1980-02-19 1980-02-19

Publications (1)

Publication Number Publication Date
BE887566A true BE887566A (fr) 1981-06-15

Family

ID=22403319

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/203830A BE887566A (fr) 1980-02-19 1981-02-18 Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant

Country Status (11)

Country Link
JP (1) JPS56131552A (fr)
AU (1) AU538240B2 (fr)
BE (1) BE887566A (fr)
CA (1) CA1156655A (fr)
CH (1) CH648283A5 (fr)
DE (1) DE3105285A1 (fr)
FR (1) FR2476071A1 (fr)
GB (1) GB2071086B (fr)
IL (1) IL61945A (fr)
IT (1) IT1146744B (fr)
NL (1) NL8100808A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
WO2002078681A2 (fr) 2001-04-02 2002-10-10 Alcon, Inc. Procede permettant de traiter les troubles inflammatoires oculaires et les troubles lies a l'angiogenese du segment posterieur de l'oeil a l'aide d'un derive amide de flurbiprofen ou de ketorolac
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
CA2755314A1 (fr) * 2009-03-12 2010-09-16 Medichem, S.A. Nouveaux cristaux d'un derive de benzoylbenzeneacetamide
EP2389354A1 (fr) * 2009-04-06 2011-11-30 Medichem, S.A. 2-{2-amino-3-ýhydroxy(phényl)méthyl¨phényl}acétamine
CN106631881B (zh) * 2016-09-08 2018-09-21 南京工业大学 2-(3-苄基-2-(二甲基氨基)苯基)乙酰胺及合成方法和用途
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
FR2366015A1 (fr) * 1975-11-05 1978-04-28 Robins Co Inc A H Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Also Published As

Publication number Publication date
IL61945A0 (en) 1981-02-27
FR2476071B1 (fr) 1984-05-11
GB2071086B (en) 1984-02-08
IT8167177A0 (it) 1981-02-09
JPH0153266B2 (fr) 1989-11-13
JPS56131552A (en) 1981-10-15
AU6733081A (en) 1981-08-27
AU538240B2 (en) 1984-08-02
NL8100808A (nl) 1981-09-16
DE3105285A1 (de) 1982-01-21
GB2071086A (en) 1981-09-16
CA1156655A (fr) 1983-11-08
IL61945A (en) 1984-09-30
IT1146744B (it) 1986-11-19
FR2476071A1 (fr) 1981-08-21
CH648283A5 (fr) 1985-03-15

Similar Documents

Publication Publication Date Title
BE880201A (fr) Proteines purifiees, procede de preparation et compositions pharmaceutiques les contenant
BE867248A (fr) Nouveaux isomeres dextrogyres de spiro-hydantoines asymetriques et compositions pharmaceutiques les contenant
BE885812A (fr) Derives d'acides 6beta-hydroxyalkylpenicillaniques, leur procede de production et compositions pharmaceutiques les contenant
FR2567885B1 (fr) Derives 3-aminopropoxyaryliques, leur preparation, leur application comme medicaments et compositions pharmaceutiques les contenant
BE848377A (fr) Compositions stables d'erythrocytes, procede de preparation et leur application
FR2523962B1 (fr) Nouveaux amides d'acides aldoniques, leur preparation et compositions les contenant
BE887970A (fr) Nouveaux derives d'ocytocine et compositions pharmaceutiques contenant ces derives
BE887566A (fr) Nouveaux acides 2-amino-3-(alpha-hedroxybenzyl)-phenylacetiques et leur esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant
BE888797A (fr) Derives de carnitine et compositions pharmaceutiques en contenant
FR2347365A1 (fr) Trans-hexahydro-pyrido-indoles, leur preparation et compositions pharmaceutiques les contenant
DZ327A1 (fr) Imino diacides substitutes, leur préparation e composition pharmaceutiques les contenant.
FR2553409B1 (fr) Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
PT78275B (fr) Procede de preparation de nouveaux acides flavone-carboxyliques-4' et de compositions pharmaceutiques les contenant
FR2598420B1 (fr) Nouveaux esters retinoiques d'antibiotiques, leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant
BE885156A (fr) Psoralenes, leur procede de preparation et compositions pharmaceutiques les contenant
BE887730A (fr) Nouveaux derives heterocycliques, procedes pour leur preparation et compositions pharmaceutiques les contenant
FR2343730A1 (fr) Derives d'acide amidinoformique ou d'acide amidinosulfinique, leur preparation et compositions pharmaceutiques les contenant
BE885393A (fr) Nouveaux amino-2 benzoyl-3 phenylacetamides et leurs homologues cycliques utiles comme medicaments et compositions therapeutiques et formes pharmaceutiques les contenant
BE884083A (fr) Nouveaux oxime-ethers, leur procede de preparation et compositions pharmaceutiques les contenant
BE878020A (fr) Derives n-substitues de l'acide aziridine-2-carboxylique immunostimulateurs, procedes de preparation et compositions pharmaceutiques les contenant
BE888953A (fr) Esters de derives alkoxy-acyles de carnitine, leur preparation et compositions pharmaceutiques en contenant
BE860162A (fr) Derives actifs de l'uree leur procede de preparation ainsi que les compositions therapeutiques les contenant
FR2521142B1 (fr) Nouveaux derives n-methanesulfonique de la demethyl-3-o istamycine b, leur preparation et compositions therapeutiques en contenant
LU81182A1 (fr) Nouveaux derives de l'isoquinoleine,leur preparation et les compositions pharmaceutiques qui les contiennent
FR2344545A1 (fr) Amides d'acides (2-pyrimidinylthio)-alcanoiques ayant une activite antilipemique, procedes pour leur preparation et compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: A.H. ROBINS CY INC.

Effective date: 19920228