JPS56131552A - Novel phenylacetic acid compound and antiinflammatory thereof - Google Patents

Novel phenylacetic acid compound and antiinflammatory thereof

Info

Publication number
JPS56131552A
JPS56131552A JP2363881A JP2363881A JPS56131552A JP S56131552 A JPS56131552 A JP S56131552A JP 2363881 A JP2363881 A JP 2363881A JP 2363881 A JP2363881 A JP 2363881A JP S56131552 A JPS56131552 A JP S56131552A
Authority
JP
Japan
Prior art keywords
antiinflammatory
acid compound
phenylacetic acid
novel phenylacetic
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2363881A
Other languages
Japanese (ja)
Other versions
JPH0153266B2 (en
Inventor
Jiyon Uerusutetsudo Ji Uiriamu
Uein Moran Henrii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of JPS56131552A publication Critical patent/JPS56131552A/en
Publication of JPH0153266B2 publication Critical patent/JPH0153266B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2363881A 1980-02-19 1981-02-19 Novel phenylacetic acid compound and antiinflammatory thereof Granted JPS56131552A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12254480A 1980-02-19 1980-02-19

Publications (2)

Publication Number Publication Date
JPS56131552A true JPS56131552A (en) 1981-10-15
JPH0153266B2 JPH0153266B2 (en) 1989-11-13

Family

ID=22403319

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2363881A Granted JPS56131552A (en) 1980-02-19 1981-02-19 Novel phenylacetic acid compound and antiinflammatory thereof

Country Status (11)

Country Link
JP (1) JPS56131552A (en)
AU (1) AU538240B2 (en)
BE (1) BE887566A (en)
CA (1) CA1156655A (en)
CH (1) CH648283A5 (en)
DE (1) DE3105285A1 (en)
FR (1) FR2476071A1 (en)
GB (1) GB2071086B (en)
IL (1) IL61945A (en)
IT (1) IT1146744B (en)
NL (1) NL8100808A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030346A1 (en) 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
AU2002247284A1 (en) 2001-04-02 2002-10-15 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
CN102438979A (en) * 2009-03-12 2012-05-02 麦迪凯姆股份公司 New crystals of a benzoylbenzeneacetamide derivative
EP2389354A1 (en) * 2009-04-06 2011-11-30 Medichem, S.A. 2-{2-amino-3-ýhydroxy(phenyl)methyl¨phenyl} acetamide
CN106631881B (en) * 2016-09-08 2018-09-21 南京工业大学 2-（3- benzyls -2-（Dimethylamino）Phenyl）Acetamide and preparation method and use
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH577461A5 (en) * 1975-08-13 1976-07-15 Robins Co Inc A H
FR2366015A1 (en) * 1975-11-05 1978-04-28 Robins Co Inc A H Amino-benzoyl-phenylacetic acid derivs - antiinflammatory, hypocholesterolemic and blood platelet agglomeration inhibitory activity
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Also Published As

Publication number Publication date
IT8167177A0 (en) 1981-02-09
IL61945A0 (en) 1981-02-27
CH648283A5 (en) 1985-03-15
BE887566A (en) 1981-06-15
AU538240B2 (en) 1984-08-02
JPH0153266B2 (en) 1989-11-13
NL8100808A (en) 1981-09-16
IT1146744B (en) 1986-11-19
DE3105285A1 (en) 1982-01-21
CA1156655A (en) 1983-11-08
GB2071086A (en) 1981-09-16
GB2071086B (en) 1984-02-08
FR2476071A1 (en) 1981-08-21
FR2476071B1 (en) 1984-05-11
IL61945A (en) 1984-09-30
AU6733081A (en) 1981-08-27

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