IT8167177A0 - 2 AMINO 3 HYDROXY PHENYL ME TEL PHENYLACETIC ACIDS THEIR ESTERS AND AMIDES PARTICULARLY USEFUL AS ANTI-INFLAMMATORS - Google Patents

2 AMINO 3 HYDROXY PHENYL ME TEL PHENYLACETIC ACIDS THEIR ESTERS AND AMIDES PARTICULARLY USEFUL AS ANTI-INFLAMMATORS

Info

Publication number
IT8167177A0
IT8167177A0 IT8167177A IT6717781A IT8167177A0 IT 8167177 A0 IT8167177 A0 IT 8167177A0 IT 8167177 A IT8167177 A IT 8167177A IT 6717781 A IT6717781 A IT 6717781A IT 8167177 A0 IT8167177 A0 IT 8167177A0
Authority
IT
Italy
Prior art keywords
inflammators
tel
esters
amino
particularly useful
Prior art date
Application number
IT8167177A
Other languages
Italian (it)
Other versions
IT1146744B (en
Inventor
William John Welstead Jr
Henry Wayne Moran
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IT8167177A0 publication Critical patent/IT8167177A0/en
Application granted granted Critical
Publication of IT1146744B publication Critical patent/IT1146744B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
IT67177/81A 1980-02-19 1981-02-09 ACIDS 2 AMINO 3 HYDROXY PHENYL METHYL PHENYLACETICS THEIR ESTERS AND STARCHES PARTICULARLY USEFUL AS ANTI-INFLAMMATORY IT1146744B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12254480A 1980-02-19 1980-02-19

Publications (2)

Publication Number Publication Date
IT8167177A0 true IT8167177A0 (en) 1981-02-09
IT1146744B IT1146744B (en) 1986-11-19

Family

ID=22403319

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67177/81A IT1146744B (en) 1980-02-19 1981-02-09 ACIDS 2 AMINO 3 HYDROXY PHENYL METHYL PHENYLACETICS THEIR ESTERS AND STARCHES PARTICULARLY USEFUL AS ANTI-INFLAMMATORY

Country Status (11)

Country Link
JP (1) JPS56131552A (en)
AU (1) AU538240B2 (en)
BE (1) BE887566A (en)
CA (1) CA1156655A (en)
CH (1) CH648283A5 (en)
DE (1) DE3105285A1 (en)
FR (1) FR2476071A1 (en)
GB (1) GB2071086B (en)
IL (1) IL61945A (en)
IT (1) IT1146744B (en)
NL (1) NL8100808A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
AR030346A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE
WO2002078681A2 (en) 2001-04-02 2002-10-10 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
US20100234469A1 (en) * 2009-03-12 2010-09-16 Medichem, S.A. New Crystals Of A Benzoylbenzeneacetamide Derivative
EP2389354A1 (en) * 2009-04-06 2011-11-30 Medichem, S.A. 2-{2-amino-3-ýhydroxy(phenyl)methyl¨phenyl} acetamide
CN106631881B (en) * 2016-09-08 2018-09-21 南京工业大学 2-（3- benzyls -2-（Dimethylamino）Phenyl）Acetamide and preparation method and use
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE400966B (en) * 1975-08-13 1978-04-17 Robins Co Inc A H PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS
FR2366015A1 (en) * 1975-11-05 1978-04-28 Robins Co Inc A H Amino-benzoyl-phenylacetic acid derivs - antiinflammatory, hypocholesterolemic and blood platelet agglomeration inhibitory activity
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Also Published As

Publication number Publication date
AU6733081A (en) 1981-08-27
IL61945A (en) 1984-09-30
FR2476071A1 (en) 1981-08-21
CA1156655A (en) 1983-11-08
JPS56131552A (en) 1981-10-15
CH648283A5 (en) 1985-03-15
IL61945A0 (en) 1981-02-27
JPH0153266B2 (en) 1989-11-13
BE887566A (en) 1981-06-15
GB2071086A (en) 1981-09-16
NL8100808A (en) 1981-09-16
DE3105285A1 (en) 1982-01-21
GB2071086B (en) 1984-02-08
FR2476071B1 (en) 1984-05-11
IT1146744B (en) 1986-11-19
AU538240B2 (en) 1984-08-02

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