GB2071086B - 2-amino-3-(hydroxy (phenyl) methyl) phenylacetic acids esters and amides - Google Patents
2-amino-3-(hydroxy (phenyl) methyl) phenylacetic acids esters and amidesInfo
- Publication number
- GB2071086B GB2071086B GB8105091A GB8105091A GB2071086B GB 2071086 B GB2071086 B GB 2071086B GB 8105091 A GB8105091 A GB 8105091A GB 8105091 A GB8105091 A GB 8105091A GB 2071086 B GB2071086 B GB 2071086B
- Authority
- GB
- United Kingdom
- Prior art keywords
- amides
- hydroxy
- phenyl
- amino
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12254480A | 1980-02-19 | 1980-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2071086A GB2071086A (en) | 1981-09-16 |
GB2071086B true GB2071086B (en) | 1984-02-08 |
Family
ID=22403319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB8105091A Expired GB2071086B (en) | 1980-02-19 | 1981-02-18 | 2-amino-3-(hydroxy (phenyl) methyl) phenylacetic acids esters and amides |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS56131552A (en) |
AU (1) | AU538240B2 (en) |
BE (1) | BE887566A (en) |
CA (1) | CA1156655A (en) |
CH (1) | CH648283A5 (en) |
DE (1) | DE3105285A1 (en) |
FR (1) | FR2476071A1 (en) |
GB (1) | GB2071086B (en) |
IL (1) | IL61945A (en) |
IT (1) | IT1146744B (en) |
NL (1) | NL8100808A (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA805476B (en) * | 1979-09-26 | 1981-11-25 | Robins Co Inc A H | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
IL64724A0 (en) * | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
AR030346A1 (en) | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE |
AR030345A1 (en) * | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS |
AU2002247284A1 (en) | 2001-04-02 | 2002-10-15 | Alcon, Inc. | Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac |
TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
CN102438979A (en) * | 2009-03-12 | 2012-05-02 | 麦迪凯姆股份公司 | New crystals of a benzoylbenzeneacetamide derivative |
US20120111098A1 (en) * | 2009-04-06 | 2012-05-10 | Medichem, S.A. | 2- acetamide |
CN106631881B (en) * | 2016-09-08 | 2018-09-21 | 南京工业大学 | 2-(3- benzyls -2-(Dimethylamino)Phenyl)Acetamide and preparation method and use |
CN112794809B (en) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | Preparation method of high-purity nepafenac intermediate |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE400966B (en) * | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS |
FR2366015A1 (en) * | 1975-11-05 | 1978-04-28 | Robins Co Inc A H | Amino-benzoyl-phenylacetic acid derivs - antiinflammatory, hypocholesterolemic and blood platelet agglomeration inhibitory activity |
ZA805476B (en) * | 1979-09-26 | 1981-11-25 | Robins Co Inc A H | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
-
1981
- 1981-01-20 IL IL61945A patent/IL61945A/en unknown
- 1981-02-09 IT IT67177/81A patent/IT1146744B/en active
- 1981-02-13 DE DE19813105285 patent/DE3105285A1/en not_active Withdrawn
- 1981-02-16 AU AU67330/81A patent/AU538240B2/en not_active Ceased
- 1981-02-18 NL NL8100808A patent/NL8100808A/en not_active Application Discontinuation
- 1981-02-18 BE BE0/203830A patent/BE887566A/en not_active IP Right Cessation
- 1981-02-18 GB GB8105091A patent/GB2071086B/en not_active Expired
- 1981-02-18 CA CA000371185A patent/CA1156655A/en not_active Expired
- 1981-02-18 FR FR8103188A patent/FR2476071A1/en active Granted
- 1981-02-18 CH CH1076/81A patent/CH648283A5/en not_active IP Right Cessation
- 1981-02-19 JP JP2363881A patent/JPS56131552A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS56131552A (en) | 1981-10-15 |
GB2071086A (en) | 1981-09-16 |
IL61945A0 (en) | 1981-02-27 |
CA1156655A (en) | 1983-11-08 |
CH648283A5 (en) | 1985-03-15 |
JPH0153266B2 (en) | 1989-11-13 |
IT1146744B (en) | 1986-11-19 |
AU6733081A (en) | 1981-08-27 |
IT8167177A0 (en) | 1981-02-09 |
DE3105285A1 (en) | 1982-01-21 |
AU538240B2 (en) | 1984-08-02 |
FR2476071A1 (en) | 1981-08-21 |
FR2476071B1 (en) | 1984-05-11 |
IL61945A (en) | 1984-09-30 |
BE887566A (en) | 1981-06-15 |
NL8100808A (en) | 1981-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |