FR2455588A1 - Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence reduction hydrogene) - Google Patents

Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence reduction hydrogene)

Info

Publication number
FR2455588A1
FR2455588A1 FR8009732A FR8009732A FR2455588A1 FR 2455588 A1 FR2455588 A1 FR 2455588A1 FR 8009732 A FR8009732 A FR 8009732A FR 8009732 A FR8009732 A FR 8009732A FR 2455588 A1 FR2455588 A1 FR 2455588A1
Authority
FR
France
Prior art keywords
isopropylamino
pyrimidine
preparation
hydroxyl derivatives
hydrogen reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8009732A
Other languages
English (en)
Other versions
FR2455588B1 (fr
Inventor
Andre Esanu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ugine Kuhlmann SA
Original Assignee
Ugine Kuhlmann SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ugine Kuhlmann SA filed Critical Ugine Kuhlmann SA
Publication of FR2455588A1 publication Critical patent/FR2455588A1/fr
Application granted granted Critical
Publication of FR2455588B1 publication Critical patent/FR2455588B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

L'INVENTION CONCERNE UN PROCEDE DE PREPARATION DES DERIVES HYDROXYLES DE L'ISOPROPYLAMINO-PYRIMIDINE REPONDANT A LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE A, A ET A REPRESENTENT CHACUN:-UN ATOME D'HYDROGENE;-UN RADICAL HYDROXY;AVEC LA RESTRICTION QU'AU MOINS L'UN DES SUBSTITUANTS A, A ET A N'EST PAS UN ATOME D'HYDROGENE, CONSISTANT A REDUIRE L'ISOPROPYLAMINO-2 ARALCOYLOXY OU ALCOYLOXY PYRIMIDINE CORRESPONDANTE PAR L'HYDROGENE, SOUS PRESSION NORMALE ET EN PRESENCE D'UN CATALYSEUR D'HYDROGENATION.
FR8009732A 1979-04-30 1980-04-30 Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence reduction hydrogene) Granted FR2455588A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7914987 1979-04-30

Publications (2)

Publication Number Publication Date
FR2455588A1 true FR2455588A1 (fr) 1980-11-28
FR2455588B1 FR2455588B1 (fr) 1983-04-15

Family

ID=10504858

Family Applications (2)

Application Number Title Priority Date Filing Date
FR8009733A Granted FR2455589A1 (fr) 1979-04-30 1980-04-30 Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence base minerale)
FR8009732A Granted FR2455588A1 (fr) 1979-04-30 1980-04-30 Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence reduction hydrogene)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR8009733A Granted FR2455589A1 (fr) 1979-04-30 1980-04-30 Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence base minerale)

Country Status (26)

Country Link
JP (2) JPS55145670A (fr)
AR (2) AR222869A1 (fr)
AT (2) AT380012B (fr)
BE (2) BE882594A (fr)
CH (2) CH645361A5 (fr)
DK (2) DK183780A (fr)
EG (2) EG14284A (fr)
ES (2) ES490999A0 (fr)
FI (2) FI66358C (fr)
FR (2) FR2455589A1 (fr)
GB (2) GB2054556B (fr)
HK (2) HK55683A (fr)
IE (2) IE49591B1 (fr)
IN (2) IN154067B (fr)
IT (2) IT1141487B (fr)
LU (2) LU82332A1 (fr)
MA (1) MA18824A1 (fr)
MX (2) MX5878E (fr)
MY (2) MY8400203A (fr)
NL (2) NL8002272A (fr)
NO (2) NO154056C (fr)
NZ (2) NZ193422A (fr)
OA (2) OA06527A (fr)
PT (2) PT71155A (fr)
SG (2) SG22283G (fr)
ZA (2) ZA801960B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63145595U (fr) * 1987-03-13 1988-09-26
JPS645795U (fr) * 1987-06-26 1989-01-13
JPH01100695U (fr) * 1987-12-21 1989-07-06
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/63 *

Also Published As

Publication number Publication date
NL8002271A (nl) 1980-11-03
MY8400203A (en) 1984-12-31
PT71154A (en) 1980-05-01
LU82333A1 (fr) 1980-07-02
ZA801960B (en) 1981-04-29
FI801084A (fi) 1980-10-31
HK55683A (en) 1983-11-25
ES8103061A1 (es) 1981-02-16
IN154066B (fr) 1984-09-15
ES8103060A1 (es) 1981-02-16
FI66358B (fi) 1984-06-29
NZ193422A (en) 1981-12-15
NO154056C (no) 1986-07-09
FR2455589A1 (fr) 1980-11-28
NO801234L (no) 1980-10-31
OA06527A (fr) 1981-07-31
AT380013B (de) 1986-03-25
MY8400204A (en) 1984-12-31
AR222869A1 (es) 1981-06-30
ES491000A0 (es) 1981-02-16
EG14284A (en) 1983-09-30
LU82332A1 (fr) 1980-07-02
NO154055B (no) 1986-04-01
SG22583G (en) 1983-12-16
FI801083A (fi) 1980-10-31
IN154067B (fr) 1984-09-15
IT1141487B (it) 1986-10-01
BE882594A (fr) 1980-07-31
SG22283G (en) 1983-12-16
BE882593A (fr) 1980-07-31
AR222870A1 (es) 1981-06-30
CH645361A5 (en) 1984-09-28
JPS6116272B2 (fr) 1986-04-28
HK55583A (en) 1983-11-25
ATA221580A (de) 1985-08-15
NO801235L (no) 1980-10-31
DK183780A (da) 1980-10-31
EG14259A (en) 1983-09-30
IE800865L (en) 1980-10-30
NO154055C (no) 1986-07-09
NL8002272A (nl) 1980-11-03
FI66359B (fi) 1984-06-29
AT380012B (de) 1986-03-25
FR2455588B1 (fr) 1983-04-15
MX5878E (es) 1984-08-16
GB2054556B (en) 1983-01-26
FI66358C (fi) 1984-10-10
CH645633A5 (en) 1984-10-15
ES490999A0 (es) 1981-02-16
OA06525A (fr) 1981-07-31
FR2455589B1 (fr) 1981-07-10
ATA221680A (de) 1985-08-15
JPS6116273B2 (fr) 1986-04-28
MA18824A1 (fr) 1980-12-31
MX6514E (es) 1985-06-26
NO154056B (no) 1986-04-01
IE800864L (en) 1980-10-30
IT8021542A0 (it) 1980-04-22
JPS55145670A (en) 1980-11-13
DK183880A (da) 1980-10-31
NZ193421A (en) 1981-11-19
GB2054556A (en) 1981-02-18
IE49591B1 (en) 1985-10-30
FI66359C (fi) 1984-10-10
JPS55145671A (en) 1980-11-13
IT8021543A0 (it) 1980-04-22
IE49709B1 (en) 1985-11-27
ZA801958B (en) 1981-04-29
PT71155A (en) 1980-05-01
GB2055801B (en) 1983-02-09
IT1141296B (it) 1986-10-01
GB2055801A (en) 1981-03-11

Similar Documents

Publication Publication Date Title
ES2073653T3 (es) Derivados de adenosina 2-substituidos y composiciones farmaceuticas para las enfermedades del sistema circulatorio.
FI821598A0 (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-alkyl-2-aminotetralinderivat
MY102565A (en) Novel derivatives of guanine
FR2451370A1 (fr) Derives hydroxyles de l'isopropylamino-2 pyrimidine et leur preparation
DK158085A (da) 2-substituerede ergolinderivater, fremgangsmaade til fremstilling heraf samt anvendelsen heraf som laegemiddel
ZA887260B (en) Cathartics
FR2455588A1 (fr) Preparation des derives hydroxyles de l'isopropylamino-pyrimidine (sequence reduction hydrogene)
FR2506772A1 (fr) Glycosides d'anthracycline, procede pour les preparer et leur usage comme medicament
CS643889A3 (en) Process for preparing 3,5-dimethyl-4-methoxypyridine derivatives
FI895447A0 (fi) Substituerade adeninderivat anvaendbara som terapeutiska substanser.
GB1141772A (en) 13-alkylgonahexaenes
ES2161953T3 (es) Utilizacion del monosialogangliosido gm1 o del n-dicloroacetil-liso-gm1 para prevenir o invertir la degeneracion neuronal inducida por un tratamiento de larga duracion con l-dopa en la terapia de la enfermedad de parkinson.
FR2381733A1 (fr) Procede de preparation de m-bromo-a,a,a-trifluorotoluenes
Haas-Hawkings et al. A study of relatively immediate adjustment to widowhood in later life.
ES8304111A1 (es) Procedimiento para la preparacion de 2,3-dihidro piranos.
GB1527557A (en) Process for preparing solid sodium amoxycillin
GB522440A (en) Improvements in or relating to an adjustable back-rest for a bedstead, divan, couch or the like
ES446874A1 (es) Un metodo para la produccion de nuevos derivados de cromona.
Bhatti et al. Social system approach to understand marital disharmony.
FR2450253A1 (fr) Derives de 2-hydroxybenzamide, composition et procede utilisant ces derives comme fongicides
SE8206352D0 (sv) Sett att framstella bensylalkoholderivat
FR2387972A1 (fr) Procede de preparation du (1-chlorethenyl)-oxiranne
MX160562A (es) Un proceso para preparar derivados de cloruro de aninosulfenilo
USD201045S (en) Vvvv vvvvvvv
Moutsos Hesychian βράγος

Legal Events

Date Code Title Description
ST Notification of lapse