ES8103061A1 - Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina - Google Patents

Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina

Info

Publication number
ES8103061A1
ES8103061A1 ES491000A ES491000A ES8103061A1 ES 8103061 A1 ES8103061 A1 ES 8103061A1 ES 491000 A ES491000 A ES 491000A ES 491000 A ES491000 A ES 491000A ES 8103061 A1 ES8103061 A1 ES 8103061A1
Authority
ES
Spain
Prior art keywords
isopropylamino
pyrimidine
preparation
hydroxy derivatives
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491000A
Other languages
English (en)
Other versions
ES491000A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES8103061A1 publication Critical patent/ES8103061A1/es
Publication of ES491000A0 publication Critical patent/ES491000A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS HIDROXILICOS DE ISOPROPILAMINO-PIRIMIDINA DE FORMULA (I) DONDE A4, A5, Y A6 SON INDEPENDIENTEMENTE, HIDROGENO O UN GRUPO HIDROXI, PERO CON LA CONDICION DE QUE AL MENOS UNO DE ELLOS NO SEA HIDROGENO. DICHO PROCEDIMIENTO SE FUNDAMENTA EN LA REDUCCION DE LA CORRESPONDIENTE 2-ISOPROPILAMINO-ARALCOHILOXI O -ALCOHILOXI-PIRIMIDINA CON HIDROGENO, BAJO PRESION Y EN PRESION DE UN CATALIZADOR DE HIDROGENACION. COMO CATALIZADOR DE HIDROGENACION PUEDE EMPLEARSE PALADIO. LOS COMPUESTOS OBTENIDOS ON DE EMPLEO EN EL TRATAMIENTO DE NUROPATIAS Y DE DISTROFIAS MUSCULARES. *FORMULA*.
ES491000A 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina Granted ES491000A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7914987 1979-04-30

Publications (2)

Publication Number Publication Date
ES8103061A1 true ES8103061A1 (es) 1981-02-16
ES491000A0 ES491000A0 (es) 1981-02-16

Family

ID=10504858

Family Applications (2)

Application Number Title Priority Date Filing Date
ES491000A Granted ES491000A0 (es) 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina
ES490999A Granted ES490999A0 (es) 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES490999A Granted ES490999A0 (es) 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina

Country Status (26)

Country Link
JP (2) JPS55145670A (es)
AR (2) AR222869A1 (es)
AT (2) AT380013B (es)
BE (2) BE882593A (es)
CH (2) CH645361A5 (es)
DK (2) DK183780A (es)
EG (2) EG14284A (es)
ES (2) ES491000A0 (es)
FI (2) FI66359C (es)
FR (2) FR2455588A1 (es)
GB (2) GB2055801B (es)
HK (2) HK55683A (es)
IE (2) IE49591B1 (es)
IN (2) IN154067B (es)
IT (2) IT1141296B (es)
LU (2) LU82333A1 (es)
MA (1) MA18824A1 (es)
MX (2) MX5878E (es)
MY (2) MY8400203A (es)
NL (2) NL8002271A (es)
NO (2) NO154056C (es)
NZ (2) NZ193422A (es)
OA (2) OA06525A (es)
PT (2) PT71154A (es)
SG (2) SG22283G (es)
ZA (2) ZA801958B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63145595U (es) * 1987-03-13 1988-09-26
JPS645795U (es) * 1987-06-26 1989-01-13
JPH01100695U (es) * 1987-12-21 1989-07-06
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines

Also Published As

Publication number Publication date
ATA221680A (de) 1985-08-15
MX6514E (es) 1985-06-26
GB2055801A (en) 1981-03-11
PT71154A (en) 1980-05-01
ZA801960B (en) 1981-04-29
HK55583A (en) 1983-11-25
IT1141487B (it) 1986-10-01
BE882594A (fr) 1980-07-31
CH645361A5 (en) 1984-09-28
ZA801958B (en) 1981-04-29
NZ193421A (en) 1981-11-19
AR222869A1 (es) 1981-06-30
DK183880A (da) 1980-10-31
AT380013B (de) 1986-03-25
IN154066B (es) 1984-09-15
GB2054556B (en) 1983-01-26
ES8103060A1 (es) 1981-02-16
FI66358B (fi) 1984-06-29
MX5878E (es) 1984-08-16
FI66359C (fi) 1984-10-10
JPS55145671A (en) 1980-11-13
NL8002272A (nl) 1980-11-03
FI66359B (fi) 1984-06-29
SG22283G (en) 1983-12-16
BE882593A (fr) 1980-07-31
GB2054556A (en) 1981-02-18
EG14284A (en) 1983-09-30
JPS6116272B2 (es) 1986-04-28
IE800864L (en) 1980-10-30
NO801234L (no) 1980-10-31
SG22583G (en) 1983-12-16
EG14259A (en) 1983-09-30
IE800865L (en) 1980-10-30
JPS55145670A (en) 1980-11-13
NZ193422A (en) 1981-12-15
DK183780A (da) 1980-10-31
IT1141296B (it) 1986-10-01
NO154055B (no) 1986-04-01
NO154055C (no) 1986-07-09
AT380012B (de) 1986-03-25
FR2455588A1 (fr) 1980-11-28
IE49709B1 (en) 1985-11-27
OA06527A (fr) 1981-07-31
FR2455588B1 (es) 1983-04-15
FR2455589B1 (es) 1981-07-10
FI801084A (fi) 1980-10-31
NO154056B (no) 1986-04-01
IT8021543A0 (it) 1980-04-22
CH645633A5 (en) 1984-10-15
MY8400203A (en) 1984-12-31
LU82332A1 (fr) 1980-07-02
FI801083A (fi) 1980-10-31
LU82333A1 (fr) 1980-07-02
ES490999A0 (es) 1981-02-16
IN154067B (es) 1984-09-15
ES491000A0 (es) 1981-02-16
OA06525A (fr) 1981-07-31
IE49591B1 (en) 1985-10-30
MA18824A1 (fr) 1980-12-31
NO801235L (no) 1980-10-31
HK55683A (en) 1983-11-25
MY8400204A (en) 1984-12-31
FI66358C (fi) 1984-10-10
NL8002271A (nl) 1980-11-03
JPS6116273B2 (es) 1986-04-28
GB2055801B (en) 1983-02-09
AR222870A1 (es) 1981-06-30
IT8021542A0 (it) 1980-04-22
PT71155A (en) 1980-05-01
ATA221580A (de) 1985-08-15
FR2455589A1 (fr) 1980-11-28
NO154056C (no) 1986-07-09

Similar Documents

Publication Publication Date Title
CA1259998C (es)
ES477695A1 (es) Un procedimiento para preparar derivados de deshidrociclici-minoacidos.
FR2391183A1 (fr) Hydroxyalkylphenones et leur application comme photosensibilisateurs
DE3167774D1 (en) 4-substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics
BE883909A (fr) Procede de preparation de chloro-2proprionate d'alcoyle par chloration de lactate d'alcoyle
ES8103060A1 (es) Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina
ES8303279A1 (es) "procedimiento para preparar nuevos derivados de acidos fenil-alifatico-carboxilicos".
AU553893B2 (en) Imidazolidine derivatives
FR2377367A1 (fr) Procede de preparation d'alcoxy-cetones
DE3277971D1 (en) Acylamino-4-aza-1-adamantanes, process for their preparation and their therapeutic use
JPS57179160A (en) Phenethanolamine derivative
CS736482A2 (en) Zpusob vyroby novych derivatu delta ( 1,3,5 ) 3 chlorpregnanu
EP0074497A3 (en) Process for the preparation of 3-alkyl-6-methyl-beta-resorcylic-acid esters
HUT38090A (en) Process for production of derivatives of 2,2,5,2-tetraalkyl-cyclohexan-4-on-1-ol
FR2455023B1 (fr) Procede de preparation d'un chlorure d'acide chlorocarboxylique
HUT35250A (en) Process for preparing 4-quinolines
ES489925A1 (es) Procedimiento para la preparacion de n,n'-difenil-monohidra-zida de acido 2-(3-metil-3-butenil)-malonico
ES8507520A1 (es) Un procedimiento para la preparacion de nuevos compuestos de b-lactama
JPS54112847A (en) Preparation of novel 3alpha, 6alpha-dihydroxy-24-oxo-5beta-cholestane
JPS5279081A (en) Preparation of novel 7-methoxycephalosporins
FR2434142A1 (fr) Procede de preparation d'amino-hydroxyanthraquinones
JPS5436252A (en) Novel propano-anthracene derivatives and their preparation
GR63004B (en) Alunite flotation by use of alkylphosphoric compounds as collectors
JPS56135462A (en) Preparation of alpha-sulfenylacetic acid and aromatic compound having related functional group