FR2452488A1 - Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent - Google Patents

Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent

Info

Publication number
FR2452488A1
FR2452488A1 FR7908032A FR7908032A FR2452488A1 FR 2452488 A1 FR2452488 A1 FR 2452488A1 FR 7908032 A FR7908032 A FR 7908032A FR 7908032 A FR7908032 A FR 7908032A FR 2452488 A1 FR2452488 A1 FR 2452488A1
Authority
FR
France
Prior art keywords
antiulcer
pyridyl
derivs
thioamide
thiophene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7908032A
Other languages
English (en)
Other versions
FR2452488B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7908032A priority Critical patent/FR2452488A1/fr
Priority to IE620/80A priority patent/IE49570B1/en
Priority to NL8001687A priority patent/NL8001687A/nl
Priority to IL59719A priority patent/IL59719A/xx
Priority to NZ193268A priority patent/NZ193268A/xx
Priority to JP3765380A priority patent/JPS55130974A/ja
Priority to GB8010133A priority patent/GB2046265B/en
Priority to ZA00801781A priority patent/ZA801781B/xx
Priority to US06/134,311 priority patent/US4272534A/en
Priority to AU56847/80A priority patent/AU532337B2/en
Priority to PH23816A priority patent/PH14804A/en
Priority to DK135480A priority patent/DK135480A/da
Priority to DE3012142A priority patent/DE3012142C2/de
Priority to GR61565A priority patent/GR67614B/el
Priority to ES490061A priority patent/ES8101071A1/es
Priority to PT198071026A priority patent/PT71026A/pt
Priority to IT21029/80A priority patent/IT1193524B/it
Priority to FI800971A priority patent/FI66862C/fi
Priority to BE0/200026A priority patent/BE882520A/fr
Priority to NO800910A priority patent/NO153055C/no
Priority to CA000348680A priority patent/CA1134361A/fr
Priority to LU82307A priority patent/LU82307A1/fr
Priority to HU80739A priority patent/HU187273B/hu
Priority to CH247380A priority patent/CH644858A5/fr
Priority to SE8002426A priority patent/SE8002426L/xx
Priority to CS802244A priority patent/CS228508B2/cs
Publication of FR2452488A1 publication Critical patent/FR2452488A1/fr
Priority to SU813238649A priority patent/SU1037840A3/ru
Application granted granted Critical
Publication of FR2452488B1 publication Critical patent/FR2452488B1/fr
Priority to AT0239082A priority patent/AT371120B/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NOUVEAUX DERIVES DU (PYRIDYL-2)-2 TETRAHYDROTHIOPHENE DE FORMULE GENERALE I DANS LAQUELLE R REPRESENTE UN ATOME D'HYDROGENE OU UN RADICAL ALCOYLE ET R REPRESENTE UN RADICAL ALCOYLE, LEUR PREPARATION ET LES MEDICAMENTS QUI LES CONTIENNENT. CES NOUVEAUX DERIVES SONT PARTICULIEREMENT UTILES COMME ANTI-ULCERE. (CF DESSIN DANS BOPI)
FR7908032A 1979-03-30 1979-03-30 Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent Granted FR2452488A1 (fr)

Priority Applications (28)

Application Number Priority Date Filing Date Title
FR7908032A FR2452488A1 (fr) 1979-03-30 1979-03-30 Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
IE620/80A IE49570B1 (en) 1979-03-30 1980-03-20 2-(pyrid-2-yl)tetrahydrothiophene derivatives
NL8001687A NL8001687A (nl) 1979-03-30 1980-03-21 Nieuwe 2-(pyridyl-2).tetrahydrothiofeenderivaten, de bereiding ervan alsmede farmaceutische preparaten die de nieuwe derivaten bevatten.
NZ193268A NZ193268A (en) 1979-03-30 1980-03-26 2-(pyrid-2-yl)-tetrahydrothiophene derivatives and pharmaceutical compositions
JP3765380A JPS55130974A (en) 1979-03-30 1980-03-26 22*pyridoo22yl*tetrahydrothiophene derivative
GB8010133A GB2046265B (en) 1979-03-30 1980-03-26 2-(pyrid-2-yl)tetrahydrothiophene derivatives
ZA00801781A ZA801781B (en) 1979-03-30 1980-03-26 2-(pyrid-2-yl)tetrahydrothiophene derivatives
US06/134,311 US4272534A (en) 1979-03-30 1980-03-26 2-(Pyrid-2-yl)tetrahydrothiophene derivatives
AU56847/80A AU532337B2 (en) 1979-03-30 1980-03-26 2-(pyrid-2-yl) tetrahydrothiophene derivatives
PH23816A PH14804A (en) 1979-03-30 1980-03-26 Nouveaux derives du(pyridy 1-2)-2 tetrahydrothiophene,leur preparation et les medicaments qui les contiennent
IL59719A IL59719A (en) 1979-03-30 1980-03-26 2-(pyrid-2-yl)tetrahydrothiophene derivatives,process for their preparation and pharmaceutical compositions comprising the same
HU80739A HU187273B (en) 1979-03-30 1980-03-28 Process for preparing new 2-/2-pyridyl/-tetrahydro-thiophene derivatives
GR61565A GR67614B (fr) 1979-03-30 1980-03-28
ES490061A ES8101071A1 (es) 1979-03-30 1980-03-28 Procedimiento para preparar nuevos derivados de (piridil-2)-2-tetrahidrotiofeno
DK135480A DK135480A (da) 1979-03-30 1980-03-28 Fremgangsmaade til fremstilling af 2-(2-pyridyl)-tetrahydrothiopen-derivater
IT21029/80A IT1193524B (it) 1979-03-30 1980-03-28 Derivati del (piridil-2)-2 tetraidrotiofene,loro preparazione,e medicamenti che li contengono
FI800971A FI66862C (fi) 1979-03-30 1980-03-28 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2-(pyridyl-2)-tetrahydrotiofenderivat
BE0/200026A BE882520A (fr) 1979-03-30 1980-03-28 Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene leur preparation et les medicaments qui les contiennent
NO800910A NO153055C (no) 1979-03-30 1980-03-28 Analogifremgangsmaate for fremstilling av terapeutisk aktive nye derivater av 2-(2-pyridyl)tetrahydrotiofen
CA000348680A CA1134361A (fr) 1979-03-30 1980-03-28 Derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
LU82307A LU82307A1 (fr) 1979-03-30 1980-03-28 Nouveaux derives du (pyridy1-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
DE3012142A DE3012142C2 (de) 1979-03-30 1980-03-28 Neue Derivate des 2-[Pyridyl(2)Jtetrahydrothiophens, ihre Herstellung und die sie enthaltenden Arzneimittel
CH247380A CH644858A5 (fr) 1979-03-30 1980-03-28 Derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent.
SE8002426A SE8002426L (sv) 1979-03-30 1980-03-28 Nya derivat av 2-(2-pyridyl)tetrahydrotiofen
PT198071026A PT71026A (en) 1979-03-30 1980-03-28 Process for preparing of new derivatives (pyridil-2)-2 tetrahidrothiofene
CS802244A CS228508B2 (cs) 1979-03-30 1980-03-31 Způsob výroby nových derivátů 2-(2-pyridyl)tetrahydrothiofenu
SU813238649A SU1037840A3 (ru) 1979-03-30 1981-02-06 Способ получени производных 2-/2-пиридил/-тетрагидротиофена
AT0239082A AT371120B (de) 1979-03-30 1982-06-21 Verfahren zur herstellung neuer derivate des 2-(pyridyl-2)-tetrahydrothiophens sowie ihrer existenten salze

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7908032A FR2452488A1 (fr) 1979-03-30 1979-03-30 Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
FR2452488A1 true FR2452488A1 (fr) 1980-10-24
FR2452488B1 FR2452488B1 (fr) 1982-06-18

Family

ID=9223756

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7908032A Granted FR2452488A1 (fr) 1979-03-30 1979-03-30 Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent

Country Status (4)

Country Link
JP (1) JPS55130974A (fr)
BE (1) BE882520A (fr)
FR (1) FR2452488A1 (fr)
ZA (1) ZA801781B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0046417A1 (fr) * 1980-08-18 1982-02-24 Rhone-Poulenc Sante Nouveaux dérivés de la thioformamide, leur préparation et les médicaments qui les contiennent
FR2511371A1 (fr) * 1981-08-11 1983-02-18 Rhone Poulenc Sante Nouveaux nitriles heterocycliques, leur preparation et leur utilisation pour la preparation de medicaments

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528849B1 (fr) * 1982-06-17 1985-06-21 Rhone Poulenc Sante Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0046417A1 (fr) * 1980-08-18 1982-02-24 Rhone-Poulenc Sante Nouveaux dérivés de la thioformamide, leur préparation et les médicaments qui les contiennent
EP0077083A1 (fr) * 1980-08-18 1983-04-20 Rhone-Poulenc Sante Nouveaux dérivés de la thioformamide, leur préparation et les médicaments qui les contiennent
FR2511371A1 (fr) * 1981-08-11 1983-02-18 Rhone Poulenc Sante Nouveaux nitriles heterocycliques, leur preparation et leur utilisation pour la preparation de medicaments
EP0073704A1 (fr) * 1981-08-11 1983-03-09 Rhone-Poulenc Sante Nouveaux nitriles hétérocycliques, leur préparation et leur utilisation pour la préparation de médicaments

Also Published As

Publication number Publication date
BE882520A (fr) 1980-09-29
JPS6134433B2 (fr) 1986-08-07
ZA801781B (en) 1981-03-25
JPS55130974A (en) 1980-10-11
FR2452488B1 (fr) 1982-06-18

Similar Documents

Publication Publication Date Title
ES8404993A1 (es) Procedimiento para preparar derivados de piridina
ES8202546A1 (es) Metodo de producir derivados de tiazolidina
GB1268243A (en) 0,2,4,5,-tetrahydro-3h,3-benzazepines
ES481632A1 (es) Procedimiento de preparacion de derivados de fenilpiperazina.
JPS55136266A (en) Derivatives of 2-imidazoline
EG17287A (en) Process for preparing of tricyclic oxindole antiinflammatory agents
ZA858418B (en) 5-alkyl-1-phenyl-2-piperazinoalkylpyrazoline-3-one compounds and methods for the preparation thereof,intermediates for use in the preparation of said compounds and medicaments containing said compounds
FR2452488A1 (fr) Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
ES474367A1 (es) Procedimiento de preparacion de nuevos derivados del benzo- (d)tiazol.
JPS5430183A (en) 3,4-dihydrocarbostyril derivative
JPS5424882A (en) Novel heterocyclic compounds and their preparation
IE44999L (en) Hydrazinopyridazine derivatives.
ES474985A1 (es) Procedimiento para la preparacion de derivados de la isoqui-noleina
JPS5414956A (en) Novel 3-amino-4-homoisotwistan derivative
ES8405020A1 (es) Un procedimiento para la preparacion de derivados de fosfolipidos.
JPS5436287A (en) Thiadiazolylthiooxacephalosporin
FR2494274B2 (fr)
JPS5711975A (en) Aminophenyltetrazole derivative and salt thereof
JPS5538301A (en) New derivative of antibiotics fortimicin and its preparation
ES8306154A1 (es) "procedimiento para la preparacion de nuevas 6 -metoxi-penicilinas".
JPS51146474A (en) Process for preparing piperidylbenzimidazole derivatives
JPS54128592A (en) Cephalosporin derivatives and its preparation
DE2963679D1 (en) Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them
JPS55104266A (en) Novel pyridone derivative
JPS5416493A (en) Novel josamycin derivatives, their salts, and their preparation

Legal Events

Date Code Title Description
ST Notification of lapse