ES474985A1 - Procedimiento para la preparacion de derivados de la isoqui-noleina - Google Patents
Procedimiento para la preparacion de derivados de la isoqui-noleinaInfo
- Publication number
- ES474985A1 ES474985A1 ES474985A ES474985A ES474985A1 ES 474985 A1 ES474985 A1 ES 474985A1 ES 474985 A ES474985 A ES 474985A ES 474985 A ES474985 A ES 474985A ES 474985 A1 ES474985 A1 ES 474985A1
- Authority
- ES
- Spain
- Prior art keywords
- isoquinoline derivatives
- alkylisoquinol
- isoquinol
- analgesic
- inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Procedimiento para la preparación de derivados de la isoquinoleina de fórmula general: ***1 en la que A representa un radical piridil-3, isoquinolil-5 ó alquil-3 isoquinolil-5 cuya parte alquilo contiene de 1 a 10 átomos de carbono de cadena recta o ramificada en sus formas ® y (S) así como sus mezclas, en estado de base o de sal de adición con un ácido, caracterizado porque se cicla una tetrahidro-1,2,3,4 isoquinoleina de fórmula general : ***2 en la que A se define como procedentemente, y a continuación se transforma eventualmente el producto obtenido en una sal de adición con un ácido.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7733890A FR2408615A1 (fr) | 1977-11-10 | 1977-11-10 | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
| FR7823469A FR2433023A2 (fr) | 1978-08-09 | 1978-08-09 | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES474985A1 true ES474985A1 (es) | 1979-04-01 |
Family
ID=26220294
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES474985A Expired ES474985A1 (es) | 1977-11-10 | 1978-11-10 | Procedimiento para la preparacion de derivados de la isoqui-noleina |
| ES474986A Expired ES474986A1 (es) | 1977-11-10 | 1978-11-10 | Procedimiento para la preparacion de derivados de la isoqui-noleina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES474986A Expired ES474986A1 (es) | 1977-11-10 | 1978-11-10 | Procedimiento para la preparacion de derivados de la isoqui-noleina |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4189480A (es) |
| JP (1) | JPS5476596A (es) |
| AR (2) | AR218943A1 (es) |
| AT (1) | AT365601B (es) |
| AU (1) | AU521104B2 (es) |
| CA (1) | CA1112642A (es) |
| CH (1) | CH635590A5 (es) |
| CS (1) | CS203934B2 (es) |
| DE (1) | DE2848926C3 (es) |
| DK (1) | DK499878A (es) |
| ES (2) | ES474985A1 (es) |
| FI (1) | FI63588C (es) |
| GB (1) | GB2007660B (es) |
| GR (1) | GR66033B (es) |
| HU (1) | HU175414B (es) |
| IL (1) | IL55903A (es) |
| IT (1) | IT1100206B (es) |
| LU (1) | LU80497A1 (es) |
| NL (1) | NL7810922A (es) |
| NO (1) | NO783770L (es) |
| NZ (1) | NZ188865A (es) |
| OA (1) | OA06082A (es) |
| PL (2) | PL113229B1 (es) |
| PT (1) | PT68769A (es) |
| SE (1) | SE7811595L (es) |
| SU (2) | SU797580A3 (es) |
| YU (2) | YU259478A (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1980000840A1 (en) * | 1978-10-12 | 1980-05-01 | Sandoz Ag | N-substituted cyclic amines,their preparation and pharmaceuticals containing them |
| FR2456110A2 (fr) * | 1979-05-09 | 1980-12-05 | Rhone Poulenc Ind | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
| FR2456111A1 (fr) * | 1979-05-09 | 1980-12-05 | Rhone Poulenc Ind | Nouveaux derives de l'indole, leur preparation et les medicaments qui les contiennent |
| DE3722827A1 (de) * | 1987-07-07 | 1989-01-19 | Schering Ag | Anellierte imino-azole und imino-azine, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider wirkung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147862A (en) * | 1974-09-18 | 1979-04-03 | Matsushita Electric Industrial Co., Ltd. | Method of preparing styryl-like compounds |
| OA05403A (fr) * | 1975-08-06 | 1981-02-28 | Rhone Poulenc Ind | Nouveaux dérivés de la thiazolo [3,4-b] isoquinoléine et leur procédé de préparation. |
| NL7800383A (nl) * | 1977-01-20 | 1978-07-24 | Rhone Poulenc Ind | Nieuwe isochinolinederivaten, de bereiding ervan en preparaten die de isochinolinederivaten bevatten. |
| NL7800385A (nl) * | 1977-02-04 | 1978-08-08 | Rhone Poulenc Ind | Nieuwe indoolderivaten, werkwijzen ter berei- ding ervan en preparaten die de nieuwe deriva- ten bevatten. |
-
1978
- 1978-10-26 SU SU782677515A patent/SU797580A3/ru active
- 1978-10-30 CA CA314,858A patent/CA1112642A/fr not_active Expired
- 1978-11-01 OA OA56648A patent/OA06082A/xx unknown
- 1978-11-02 NL NL7810922A patent/NL7810922A/xx not_active Application Discontinuation
- 1978-11-07 YU YU02594/78A patent/YU259478A/xx unknown
- 1978-11-08 NZ NZ188865A patent/NZ188865A/xx unknown
- 1978-11-08 GR GR57611A patent/GR66033B/el unknown
- 1978-11-08 CS CS787273A patent/CS203934B2/cs unknown
- 1978-11-08 PL PL1978210788A patent/PL113229B1/pl unknown
- 1978-11-08 JP JP13684978A patent/JPS5476596A/ja active Granted
- 1978-11-08 IL IL55903A patent/IL55903A/xx unknown
- 1978-11-08 US US05/958,617 patent/US4189480A/en not_active Expired - Lifetime
- 1978-11-08 PL PL1978215703A patent/PL113230B1/pl unknown
- 1978-11-08 AU AU41471/78A patent/AU521104B2/en not_active Expired
- 1978-11-09 DK DK499878A patent/DK499878A/da unknown
- 1978-11-09 PT PT68769A patent/PT68769A/pt unknown
- 1978-11-09 HU HU78RO1000A patent/HU175414B/hu unknown
- 1978-11-09 CH CH1153278A patent/CH635590A5/fr not_active IP Right Cessation
- 1978-11-09 NO NO783770A patent/NO783770L/no unknown
- 1978-11-09 LU LU80497A patent/LU80497A1/xx unknown
- 1978-11-09 SE SE7811595A patent/SE7811595L/xx unknown
- 1978-11-09 AR AR274400A patent/AR218943A1/es active
- 1978-11-09 GB GB7843907A patent/GB2007660B/en not_active Expired
- 1978-11-09 IT IT29635/78A patent/IT1100206B/it active
- 1978-11-10 AT AT0806378A patent/AT365601B/de not_active IP Right Cessation
- 1978-11-10 DE DE2848926A patent/DE2848926C3/de not_active Expired
- 1978-11-10 ES ES474985A patent/ES474985A1/es not_active Expired
- 1978-11-10 ES ES474986A patent/ES474986A1/es not_active Expired
- 1978-11-10 FI FI783440A patent/FI63588C/fi not_active IP Right Cessation
-
1979
- 1979-08-01 SU SU792790355A patent/SU867312A3/ru active
- 1979-09-20 AR AR278146A patent/AR220228A1/es active
-
1982
- 1982-10-12 YU YU02298/82A patent/YU229882A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |