FR2456110A2 - Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent - Google Patents

Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent

Info

Publication number
FR2456110A2
FR2456110A2 FR7911706A FR7911706A FR2456110A2 FR 2456110 A2 FR2456110 A2 FR 2456110A2 FR 7911706 A FR7911706 A FR 7911706A FR 7911706 A FR7911706 A FR 7911706A FR 2456110 A2 FR2456110 A2 FR 2456110A2
Authority
FR
France
Prior art keywords
new
preparation
compositions containing
derivatives
isoquinolein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7911706A
Other languages
English (en)
Other versions
FR2456110B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7911706A priority Critical patent/FR2456110A2/fr
Priority to NL8002538A priority patent/NL8002538A/nl
Priority to GB8014439A priority patent/GB2048878B/en
Priority to US06/147,121 priority patent/US4261992A/en
Priority to GR61878A priority patent/GR68072B/el
Priority to ZA00802703A priority patent/ZA802703B/xx
Priority to AU58150/80A priority patent/AU533935B2/en
Priority to JP5987380A priority patent/JPS55151593A/ja
Priority to IL6002180A priority patent/IL60021A/xx
Priority to HU801138A priority patent/HU181543B/hu
Priority to SE8003476A priority patent/SE8003476L/xx
Priority to CA000351520A priority patent/CA1134360A/fr
Priority to BE0/200531A priority patent/BE883190A/fr
Priority to NO801360A priority patent/NO801360L/no
Priority to DK200980A priority patent/DK200980A/da
Priority to CH361080A priority patent/CH643852A5/fr
Priority to LU82427A priority patent/LU82427A1/fr
Priority to DE19803017865 priority patent/DE3017865A1/de
Priority to FI801506A priority patent/FI801506A/fi
Priority to IT21955/80A priority patent/IT1131167B/it
Priority to ES491336A priority patent/ES491336A0/es
Publication of FR2456110A2 publication Critical patent/FR2456110A2/fr
Application granted granted Critical
Publication of FR2456110B2 publication Critical patent/FR2456110B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Nouveaux dérivés de l'isoquinoléine de formule générale I dans laquelle A est un radical de formule générale II dans laquelle R2 est un radical alcoyle contenant 1 à 8 atomes de carbone et n est égal à 1 ou 2, leurs formes R et S et leurs mélanges, leurs sels, leurs préparations et les médicaments qui les contiennent. Ces nouveaux dérivés sont particulièrement utiles comme anti-inflammatoires, analgésiques et antipyrétiques.
FR7911706A 1978-11-08 1979-05-09 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent Granted FR2456110A2 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR7911706A FR2456110A2 (fr) 1979-05-09 1979-05-09 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
NL8002538A NL8002538A (nl) 1979-05-09 1980-05-01 Nieuwe isochinolinederivaten, de bereiding ervan en preparaten, die de nieuwe isochinolinederivaten bevatten.
GB8014439A GB2048878B (en) 1979-05-09 1980-05-01 Isoquinoline derivatives
GR61878A GR68072B (fr) 1979-05-09 1980-05-06
ZA00802703A ZA802703B (en) 1979-05-09 1980-05-06 Isoquinoline derivatives
AU58150/80A AU533935B2 (en) 1979-05-09 1980-05-06 (1,3-thiazin)(3,4-b)isoquinoline derivatives
JP5987380A JPS55151593A (en) 1979-05-09 1980-05-06 Isoquinoline derivative and its manufacture
US06/147,121 US4261992A (en) 1979-05-09 1980-05-06 Isoquinoline derivatives
CA000351520A CA1134360A (fr) 1979-05-09 1980-05-08 Derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
SE8003476A SE8003476L (sv) 1979-05-09 1980-05-08 Isokinolinderivat
IL6002180A IL60021A (en) 1978-11-08 1980-05-08 4-((3-alkoxyalkylisoquinol-5-yl)imino)1,6,11,11a-tetrahydro(1,3-thiazino)(3,4-b)isoquinoline derivatives,a process for their preparation and pharmaceutical compositions comprising the same
BE0/200531A BE883190A (fr) 1979-05-09 1980-05-08 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
NO801360A NO801360L (no) 1979-05-09 1980-05-08 Isokinolinderivater.
DK200980A DK200980A (da) 1979-05-09 1980-05-08 Fremgangsmaade til fremstilling af et isoquinolinderivat ellet et syreadditionssalt deraf
CH361080A CH643852A5 (fr) 1979-05-09 1980-05-08 Derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent.
LU82427A LU82427A1 (fr) 1979-05-09 1980-05-08 Nouveaux derives de l'isoquinoleine,leur preparation et les compositions qui les contiennent
HU801138A HU181543B (en) 1979-05-09 1980-05-08 Process for preparing new derivatives of thiazino-isoquinoline
DE19803017865 DE3017865A1 (de) 1979-05-09 1980-05-09 Neue derivate des isochinolins, ihre herstellung und die sie enthaltenden zusammensetzungen
FI801506A FI801506A (fi) 1979-05-09 1980-05-09 Nya isokinolinderivat deras framstaellning och dessa innehaollande foereningar
IT21955/80A IT1131167B (it) 1979-05-09 1980-05-09 Derivati dell'isochinolina,loro preparazione e composizioni che li contengono
ES491336A ES491336A0 (es) 1979-05-09 1980-05-09 Procedimiento para la preparacion de derivados de la isoqui-noleina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7911706A FR2456110A2 (fr) 1979-05-09 1979-05-09 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
FR2456110A2 true FR2456110A2 (fr) 1980-12-05
FR2456110B2 FR2456110B2 (fr) 1982-05-21

Family

ID=9225233

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7911706A Granted FR2456110A2 (fr) 1978-11-08 1979-05-09 Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent

Country Status (20)

Country Link
US (1) US4261992A (fr)
JP (1) JPS55151593A (fr)
AU (1) AU533935B2 (fr)
BE (1) BE883190A (fr)
CA (1) CA1134360A (fr)
CH (1) CH643852A5 (fr)
DE (1) DE3017865A1 (fr)
DK (1) DK200980A (fr)
ES (1) ES491336A0 (fr)
FI (1) FI801506A (fr)
FR (1) FR2456110A2 (fr)
GB (1) GB2048878B (fr)
GR (1) GR68072B (fr)
HU (1) HU181543B (fr)
IT (1) IT1131167B (fr)
LU (1) LU82427A1 (fr)
NL (1) NL8002538A (fr)
NO (1) NO801360L (fr)
SE (1) SE8003476L (fr)
ZA (1) ZA802703B (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2635516A1 (de) * 1975-08-06 1977-02-17 Rhone Poulenc Ind Neue derivate des thiazolo-eckige klammer auf 3,4-b eckige klammer zu-isochinolins, ihre herstellung und die sie enthaltenden zusammensetzungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU797580A3 (ru) * 1977-11-10 1981-01-15 Рон-Пуленк Эндюстри (Фирма) Способ получени производных изохино-лиНА, иХ СОлЕй, РАцЕМАТОВ или ОпТичЕС-КиХ изОМЕРОВ
US4188482A (en) * 1978-05-04 1980-02-12 Warner-Lambert Company Thiazino indole compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2635516A1 (de) * 1975-08-06 1977-02-17 Rhone Poulenc Ind Neue derivate des thiazolo-eckige klammer auf 3,4-b eckige klammer zu-isochinolins, ihre herstellung und die sie enthaltenden zusammensetzungen

Also Published As

Publication number Publication date
JPS55151593A (en) 1980-11-26
DE3017865A1 (de) 1980-11-20
GR68072B (fr) 1981-10-29
GB2048878A (en) 1980-12-17
CA1134360A (fr) 1982-10-26
BE883190A (fr) 1980-11-10
IT8021955A0 (it) 1980-05-09
AU5815080A (en) 1980-11-13
HU181543B (en) 1983-10-28
ZA802703B (en) 1981-05-27
US4261992A (en) 1981-04-14
ES8102144A2 (es) 1980-12-16
GB2048878B (en) 1983-05-18
NL8002538A (nl) 1980-11-11
ES491336A0 (es) 1980-12-16
DK200980A (da) 1980-11-10
FI801506A (fi) 1980-11-10
FR2456110B2 (fr) 1982-05-21
IT1131167B (it) 1986-06-18
NO801360L (no) 1980-11-10
CH643852A5 (fr) 1984-06-29
SE8003476L (sv) 1980-11-10
LU82427A1 (fr) 1980-12-16
AU533935B2 (en) 1983-12-22

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