FR2378779A1 - Derives de 5-fluoro-uracile et leur application en therapeutique - Google Patents
Derives de 5-fluoro-uracile et leur application en therapeutiqueInfo
- Publication number
- FR2378779A1 FR2378779A1 FR7738495A FR7738495A FR2378779A1 FR 2378779 A1 FR2378779 A1 FR 2378779A1 FR 7738495 A FR7738495 A FR 7738495A FR 7738495 A FR7738495 A FR 7738495A FR 2378779 A1 FR2378779 A1 FR 2378779A1
- Authority
- FR
- France
- Prior art keywords
- derivatives
- uracil
- therapeutics
- fluoro
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
L'invention a pour objet des dérivés nouveaux du 5-fluorouracile et des nouvelles compositions anti-tumeurs contenant ces dérivés. Ces dérivés répondent à la formule générale :
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51154941A JPS6052708B2 (ja) | 1976-12-24 | 1976-12-24 | 5−フルオロウラシル系化合物およびそれを含有する抗腫瘍剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2378779A1 true FR2378779A1 (fr) | 1978-08-25 |
FR2378779B1 FR2378779B1 (fr) | 1980-08-22 |
Family
ID=15595270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7738495A Granted FR2378779A1 (fr) | 1976-12-24 | 1977-12-20 | Derives de 5-fluoro-uracile et leur application en therapeutique |
Country Status (14)
Country | Link |
---|---|
US (1) | US4130648A (fr) |
JP (1) | JPS6052708B2 (fr) |
AU (1) | AU519524B2 (fr) |
BE (1) | BE862213A (fr) |
CA (1) | CA1077483A (fr) |
CH (1) | CH636874A5 (fr) |
DE (1) | DE2757431A1 (fr) |
ES (1) | ES465406A1 (fr) |
FR (1) | FR2378779A1 (fr) |
GB (1) | GB1594840A (fr) |
NL (1) | NL7714205A (fr) |
PH (1) | PH12700A (fr) |
SE (1) | SE436208B (fr) |
SU (2) | SU827489A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU1235864A1 (ru) * | 1983-03-11 | 1986-06-07 | Отделение ордена Ленина института химической физики АН СССР | Нитроксильные производные 5-фторурацила,обладающие противоопухолевой активностью |
US4727077A (en) * | 1985-02-20 | 1988-02-23 | Ishihara Sangyo Kaisha Ltd. | Benzoyl urea compounds, process for their production, and antitumorous compositions containing them |
DK197486A (da) * | 1986-04-30 | 1987-10-31 | Ferring Farma Lab | 5-fluoruracilprodug |
US11584733B2 (en) | 2017-01-09 | 2023-02-21 | Shuttle Pharmaceuticals, Inc. | Selective histone deacetylase inhibitors for the treatment of human disease |
US11034667B2 (en) | 2017-01-09 | 2021-06-15 | Shuttle Pharmaceuticals, Inc. | Selective histone deacetylase inhibitors for the treatment of human disease |
US11407723B2 (en) | 2018-01-09 | 2022-08-09 | Shuttle Pharmaceuticals, Inc. | Selective histone deacetylase inhibitors for the treatment of human disease |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5324951B2 (fr) * | 1973-11-28 | 1978-07-24 |
-
1976
- 1976-12-24 JP JP51154941A patent/JPS6052708B2/ja not_active Expired
-
1977
- 1977-12-14 US US05/860,319 patent/US4130648A/en not_active Expired - Lifetime
- 1977-12-20 FR FR7738495A patent/FR2378779A1/fr active Granted
- 1977-12-21 NL NL7714205A patent/NL7714205A/xx not_active Application Discontinuation
- 1977-12-21 AU AU31825/77A patent/AU519524B2/en not_active Expired
- 1977-12-21 CH CH1581377A patent/CH636874A5/de not_active IP Right Cessation
- 1977-12-22 SE SE7714670A patent/SE436208B/sv not_active IP Right Cessation
- 1977-12-22 GB GB53541/77A patent/GB1594840A/en not_active Expired
- 1977-12-22 DE DE19772757431 patent/DE2757431A1/de not_active Withdrawn
- 1977-12-22 BE BE183769A patent/BE862213A/fr not_active IP Right Cessation
- 1977-12-23 SU SU772559705A patent/SU827489A1/ru active
- 1977-12-23 CA CA293,822A patent/CA1077483A/fr not_active Expired
- 1977-12-23 PH PH20592A patent/PH12700A/en unknown
- 1977-12-23 ES ES465406A patent/ES465406A1/es not_active Expired
-
1979
- 1979-06-18 SU SU792778129A patent/SU795469A3/ru active
Also Published As
Publication number | Publication date |
---|---|
SU795469A3 (ru) | 1981-01-07 |
US4130648A (en) | 1978-12-19 |
PH12700A (en) | 1979-07-20 |
BE862213A (fr) | 1978-04-14 |
JPS5379880A (en) | 1978-07-14 |
SE7714670L (sv) | 1978-06-25 |
GB1594840A (en) | 1981-08-05 |
SU827489A1 (ru) | 1981-05-07 |
CA1077483A (fr) | 1980-05-13 |
DE2757431A1 (de) | 1978-06-29 |
FR2378779B1 (fr) | 1980-08-22 |
AU519524B2 (en) | 1981-12-10 |
NL7714205A (nl) | 1978-06-27 |
JPS6052708B2 (ja) | 1985-11-20 |
ES465406A1 (es) | 1978-09-16 |
SE436208B (sv) | 1984-11-19 |
AU3182577A (en) | 1979-06-28 |
CH636874A5 (de) | 1983-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |