ES8306154A1 - "procedimiento para la preparacion de nuevas 6 -metoxi-penicilinas". - Google Patents
"procedimiento para la preparacion de nuevas 6 -metoxi-penicilinas".Info
- Publication number
- ES8306154A1 ES8306154A1 ES515412A ES515412A ES8306154A1 ES 8306154 A1 ES8306154 A1 ES 8306154A1 ES 515412 A ES515412 A ES 515412A ES 515412 A ES515412 A ES 515412A ES 8306154 A1 ES8306154 A1 ES 8306154A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- salts
- penicillins
- methoxy
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000004464 hydroxyphenyl group Chemical group 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Fuel Cell (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 6~C-METOXI-PENICILINAS Y DE SUS SALES CON BASES, DE FORMULA (I) O (II), EN LAS QUE A Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (III) CON UN DERIVADO DE PIRIMIDINA, EVENTUALMENTE PREPARADO EN LA MEZCLA DE REACCION, DE FORMULA (IV) O (V), EN LAS QUE A Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y B ES EL GRUPO -CNO O UN DERIVADO REACTIVO DE -NHCOOH. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, A UN PH ENTRE 2,0 Y 9,0 Y TEMPERATURAS ENTRE -20 C Y 50 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTIBACTERIANO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813134776 DE3134776A1 (de) | 1981-09-02 | 1981-09-02 | Neue 6(alpha)-methoxy-penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8306154A1 true ES8306154A1 (es) | 1983-05-01 |
| ES515412A0 ES515412A0 (es) | 1983-05-01 |
Family
ID=6140700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515412A Granted ES515412A0 (es) | 1981-09-02 | 1982-09-01 | "procedimiento para la preparacion de nuevas 6 -metoxi-penicilinas". |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4454128A (es) |
| EP (1) | EP0073454B1 (es) |
| JP (1) | JPS5852293A (es) |
| AT (1) | ATE13061T1 (es) |
| AU (1) | AU553027B2 (es) |
| CA (1) | CA1206147A (es) |
| CS (1) | CS235024B2 (es) |
| DD (1) | DD203912A5 (es) |
| DE (2) | DE3134776A1 (es) |
| DK (1) | DK389182A (es) |
| ES (1) | ES515412A0 (es) |
| FI (1) | FI75826C (es) |
| GB (1) | GB2105332B (es) |
| GR (1) | GR77273B (es) |
| HU (1) | HU186570B (es) |
| IL (1) | IL66692A (es) |
| NO (1) | NO822947L (es) |
| NZ (1) | NZ201781A (es) |
| PH (1) | PH20017A (es) |
| PL (1) | PL129513B1 (es) |
| PT (1) | PT75495B (es) |
| SU (1) | SU1088666A3 (es) |
| ZA (1) | ZA826381B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0091755A1 (en) * | 1982-04-03 | 1983-10-19 | Beecham Group Plc | Penicillin derivatives, a process for their preparation and compositions containing them |
| DE3479731D1 (en) * | 1983-07-07 | 1989-10-19 | Beecham Group Plc | Substituted phenylglycine derivatives of beta-lactam antibiotics |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2710979A1 (de) * | 1977-03-14 | 1978-09-21 | Merck Patent Gmbh | Lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
| ES477520A1 (es) * | 1978-02-25 | 1979-06-01 | Thomae Gmbh Dr K | Procedimiento para la preparacion de nuevas penicilinas. |
| DE2924948A1 (de) * | 1979-06-21 | 1981-01-22 | Thomae Gmbh Dr K | Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| EP0091755A1 (en) * | 1982-04-03 | 1983-10-19 | Beecham Group Plc | Penicillin derivatives, a process for their preparation and compositions containing them |
-
1981
- 1981-09-02 DE DE19813134776 patent/DE3134776A1/de not_active Withdrawn
-
1982
- 1982-08-17 SU SU823478479A patent/SU1088666A3/ru active
- 1982-08-20 US US06/410,007 patent/US4454128A/en not_active Expired - Fee Related
- 1982-08-24 AT AT82107745T patent/ATE13061T1/de not_active IP Right Cessation
- 1982-08-24 EP EP82107745A patent/EP0073454B1/de not_active Expired
- 1982-08-24 DE DE8282107745T patent/DE3263408D1/de not_active Expired
- 1982-08-31 PL PL1982238091A patent/PL129513B1/pl unknown
- 1982-08-31 GR GR69168A patent/GR77273B/el unknown
- 1982-08-31 DD DD82242908A patent/DD203912A5/de unknown
- 1982-08-31 DK DK389182A patent/DK389182A/da not_active Application Discontinuation
- 1982-08-31 FI FI823002A patent/FI75826C/fi not_active IP Right Cessation
- 1982-09-01 NZ NZ201781A patent/NZ201781A/en unknown
- 1982-09-01 AU AU87927/82A patent/AU553027B2/en not_active Ceased
- 1982-09-01 PT PT75495A patent/PT75495B/pt unknown
- 1982-09-01 PH PH27807A patent/PH20017A/en unknown
- 1982-09-01 ZA ZA826381A patent/ZA826381B/xx unknown
- 1982-09-01 ES ES515412A patent/ES515412A0/es active Granted
- 1982-09-01 JP JP57152494A patent/JPS5852293A/ja active Pending
- 1982-09-01 CS CS826356A patent/CS235024B2/cs unknown
- 1982-09-01 NO NO822947A patent/NO822947L/no unknown
- 1982-09-01 GB GB08224916A patent/GB2105332B/en not_active Expired
- 1982-09-01 HU HU822809A patent/HU186570B/hu unknown
- 1982-09-01 CA CA000410580A patent/CA1206147A/en not_active Expired
- 1982-09-01 IL IL66692A patent/IL66692A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4454128A (en) | 1984-06-12 |
| CA1206147A (en) | 1986-06-17 |
| IL66692A0 (en) | 1982-12-31 |
| PL238091A1 (en) | 1983-03-28 |
| ATE13061T1 (de) | 1985-05-15 |
| DD203912A5 (de) | 1983-11-09 |
| DE3263408D1 (en) | 1985-06-05 |
| FI823002A0 (fi) | 1982-08-31 |
| SU1088666A3 (ru) | 1984-04-23 |
| CS235024B2 (en) | 1985-04-16 |
| FI823002L (fi) | 1983-03-03 |
| DK389182A (da) | 1983-03-03 |
| IL66692A (en) | 1985-08-30 |
| NZ201781A (en) | 1985-10-11 |
| GR77273B (es) | 1984-09-11 |
| FI75826B (fi) | 1988-04-29 |
| PT75495A (de) | 1982-10-01 |
| PL129513B1 (en) | 1984-05-31 |
| EP0073454A3 (en) | 1983-04-06 |
| EP0073454A2 (de) | 1983-03-09 |
| AU8792782A (en) | 1983-03-10 |
| ZA826381B (en) | 1984-05-30 |
| HU186570B (en) | 1985-08-28 |
| JPS5852293A (ja) | 1983-03-28 |
| FI75826C (fi) | 1988-08-08 |
| NO822947L (no) | 1983-03-03 |
| DE3134776A1 (de) | 1983-03-10 |
| GB2105332B (en) | 1985-02-06 |
| AU553027B2 (en) | 1986-07-03 |
| PT75495B (de) | 1985-11-12 |
| ES515412A0 (es) | 1983-05-01 |
| PH20017A (en) | 1986-09-01 |
| GB2105332A (en) | 1983-03-23 |
| EP0073454B1 (de) | 1985-05-02 |
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