GB1322153A - Carbonyldioxymorphinan derivatives - Google Patents

Carbonyldioxymorphinan derivatives

Info

Publication number
GB1322153A
GB1322153A GB1322153DA GB1322153A GB 1322153 A GB1322153 A GB 1322153A GB 1322153D A GB1322153D A GB 1322153DA GB 1322153 A GB1322153 A GB 1322153A
Authority
GB
United Kingdom
Prior art keywords
formula
morphinan
carbonyldioxymorphinan
derivatives
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of GB1322153A publication Critical patent/GB1322153A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1322153 Morphinan carbonates YAMANOUCHI PHARMACEUTICAL CO Ltd 15 March 1971 6842/71 Heading C2C Novel compounds of the Formula (I): wherein R is alkyl or N-methyl-morphinan-3-yl group, and non-toxic acid addition salts thereof, may be obtained by reacting 3-hydroxy-N- methylmorphinan and a compound of the formula R<SP>1</SP>-CO-X, wherein X is halogen and R<SP>1</SP> denotes an alkoxy group or a halogen atom, and optionally treating the product with a pharmaceutically non-toxic inorganic or organic acid. The morphinan starting material may be the d, l or dl isomers. Pharmaceutical compositions having antitussive activity comprise compounds of Formula I and the usual excipients in forms suitable for oral or parenteral administration.
GB1322153D 1971-03-15 1971-03-15 Carbonyldioxymorphinan derivatives Expired GB1322153A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB684271 1971-03-15

Publications (1)

Publication Number Publication Date
GB1322153A true GB1322153A (en) 1973-07-04

Family

ID=9821749

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1322153D Expired GB1322153A (en) 1971-03-15 1971-03-15 Carbonyldioxymorphinan derivatives

Country Status (1)

Country Link
GB (1) GB1322153A (en)

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees