ES479378A1 - Un procedimiento para la preparacion de compuestos de cefa- losporina. - Google Patents
Un procedimiento para la preparacion de compuestos de cefa- losporina.Info
- Publication number
- ES479378A1 ES479378A1 ES479378A ES479378A ES479378A1 ES 479378 A1 ES479378 A1 ES 479378A1 ES 479378 A ES479378 A ES 479378A ES 479378 A ES479378 A ES 479378A ES 479378 A1 ES479378 A1 ES 479378A1
- Authority
- ES
- Spain
- Prior art keywords
- cephalosporin compounds
- compounds
- cephalosporin
- phosphonocarbamoyloxymethyl
- alkylthio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- -1 Cephalosporin compounds Chemical class 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compuestos de 3-fosfonocarbamoiloximetilcefalosporina de fórmula **fórmula** (donde R1 representa un grupo acilamido, convenientemente uno que contiene 1 a 40, por ejemplo 1a 25 átomos de carbono, y R3 representa hidrógeno o un grupo alcohilo, alcohiltio o alcoxi inferior (por ejemplo de C1-4 por ejemplo un grupo metoxi y sus derivados no tóxicos. La fórmula (i) es una fórmula esqueltal y se pretende que comprenda análogos estrechamente relacionadosos tales como 2-metil, 2-metilen y 2,2-dimetilcefalosporinas. La expresión "no toxico" aplicada a os derivados de los compuestos de fórmula I) de la invención significa los derivados que son fisiológicamente aceptables en las dosis a las que se administran. Tales derivados pueden incluir, por ejemplo, sales, ésteres fisiológicamente aceptables, 1- óxidos y solvatos, por ejemplo hidratos, de los compuestos de fórmula (I) y si es apropiados , sus combinaciones.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1380178 | 1978-04-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES479378A1 true ES479378A1 (es) | 1980-01-16 |
Family
ID=10029648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES479378A Expired ES479378A1 (es) | 1978-04-07 | 1979-04-06 | Un procedimiento para la preparacion de compuestos de cefa- losporina. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4252974A (es) |
| CA (1) | CA1128930A (es) |
| ES (1) | ES479378A1 (es) |
| FR (1) | FR2429794A1 (es) |
| PT (1) | PT69450A (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5559194A (en) * | 1978-09-21 | 1980-05-02 | Glaxo Group Ltd | Manufacture of cephalosporin compound |
| US4327093A (en) * | 1978-10-24 | 1982-04-27 | Fujisawa Pharmaceutical Co., Ltd. | 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds |
| GB8810394D0 (en) * | 1988-05-03 | 1988-06-08 | Glaxo Group Ltd | Chemical process |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE664955A (es) * | 1964-06-05 | |||
| US3974153A (en) * | 1971-05-14 | 1976-08-10 | Glaxo Laboratories Limited | 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids |
| US3875152A (en) * | 1971-11-09 | 1975-04-01 | American Home Prod | Intermediates for producing semi-synthetic cephalosporins and methods of production |
| US3905963A (en) * | 1972-01-25 | 1975-09-16 | Lilly Co Eli | Process for preparing primary 3-carbamoyloxymethyl cephalosporins |
| GB1519997A (en) * | 1974-09-20 | 1978-08-02 | Sumitomo Chemical Co | Preparation o peptides and cephalosporis |
-
1979
- 1979-04-06 CA CA325,091A patent/CA1128930A/en not_active Expired
- 1979-04-06 PT PT69450A patent/PT69450A/pt unknown
- 1979-04-06 ES ES479378A patent/ES479378A1/es not_active Expired
- 1979-04-06 US US06/027,805 patent/US4252974A/en not_active Expired - Lifetime
- 1979-09-19 FR FR7923294A patent/FR2429794A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4252974A (en) | 1981-02-24 |
| FR2429794B1 (es) | 1983-03-25 |
| PT69450A (en) | 1979-05-01 |
| CA1128930A (en) | 1982-08-03 |
| FR2429794A1 (fr) | 1980-01-25 |
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