FR2448901A1 - Colle servant a reunir des tissus humains ou d'animaux, procede permettant sa fabrication et applications d'une telle colle - Google Patents

Colle servant a reunir des tissus humains ou d'animaux, procede permettant sa fabrication et applications d'une telle colle

Info

Publication number
FR2448901A1
FR2448901A1 FR8002166A FR8002166A FR2448901A1 FR 2448901 A1 FR2448901 A1 FR 2448901A1 FR 8002166 A FR8002166 A FR 8002166A FR 8002166 A FR8002166 A FR 8002166A FR 2448901 A1 FR2448901 A1 FR 2448901A1
Authority
FR
France
Prior art keywords
glue
fibrinogen
factor xiii
animals
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8002166A
Other languages
English (en)
French (fr)
Other versions
FR2448901B1 (
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Immuno AG
Immuno AG fuer Chemisch Medizinische Produkte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3508554&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2448901(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immuno AG, Immuno AG fuer Chemisch Medizinische Produkte filed Critical Immuno AG
Publication of FR2448901A1 publication Critical patent/FR2448901A1/fr
Application granted granted Critical
Publication of FR2448901B1 publication Critical patent/FR2448901B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Adhesives Or Adhesive Processes (AREA)
FR8002166A 1979-02-15 1980-01-31 Colle servant a reunir des tissus humains ou d'animaux, procede permettant sa fabrication et applications d'une telle colle Granted FR2448901A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT119079A AT359653B (de) 1979-02-15 1979-02-15 Verfahren zur herstellung eines gewebekleb- stoffes

Publications (2)

Publication Number Publication Date
FR2448901A1 true FR2448901A1 (fr) 1980-09-12
FR2448901B1 FR2448901B1 ( ) 1984-09-07

Family

ID=3508554

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8002166A Granted FR2448901A1 (fr) 1979-02-15 1980-01-31 Colle servant a reunir des tissus humains ou d'animaux, procede permettant sa fabrication et applications d'une telle colle

Country Status (15)

Country Link
US (2) US4298598A ( )
JP (1) JPS55110557A ( )
AR (2) AR226837A1 ( )
AT (1) AT359653B ( )
BE (1) BE881467A ( )
CA (1) CA1119516A ( )
CH (1) CH649925A5 ( )
DE (1) DE3002933C2 ( )
DK (1) DK151611B ( )
ES (1) ES8101382A1 ( )
FR (1) FR2448901A1 ( )
GB (1) GB2042556B ( )
IT (1) IT1141212B ( )
NL (1) NL190748B ( )
SE (2) SE453800B ( )

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253198A1 (de) * 1986-07-05 1988-01-20 BEHRINGWERKE Aktiengesellschaft Einkomponenten-Gewebekleber sowie Verfahren zu seiner Herstellung
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US7078232B2 (en) 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
WO2011061705A1 (fr) 2009-11-18 2011-05-26 Lfb Biomedicaments Procede de traitement du plasma sanguin comprenant une etape de lavage par dispersion
US8383104B2 (en) 2005-12-16 2013-02-26 Laboratoire Francais Du Fractionnement Et Des Biotechnologies S.A. Thrombin-free biological adhesive and use thereof as a medicament
US8598319B2 (en) 2005-06-29 2013-12-03 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Process for separating proteins fibrinogen, factor XIII and biological glue from a solubilized plasma fraction and for preparing lyophilised concentrates of said proteins

Families Citing this family (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287777A (en) * 1976-09-13 1981-09-08 Bunker Ramo Corporation Semi-automatic contact insertion tool
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
ATE13810T1 (de) 1981-06-25 1985-07-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundabdeckung.
AT369990B (de) * 1981-07-28 1983-02-25 Immuno Ag Verfahren zur herstellung eines gewebeklebstoffes
DE3203775A1 (de) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
JP2648301B2 (ja) * 1983-12-27 1997-08-27 ジエネテイツクス・インスチチユ−ト・インコ−ポレ−テツド 真核細胞の形質転換のための補助ｄｎａを含むベクター
US4600574A (en) * 1984-03-21 1986-07-15 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of producing a tissue adhesive
US5165938A (en) * 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
US5112805A (en) * 1985-11-22 1992-05-12 Labsystems, Oy Pharmaceutical preparation for promoting epithelial healing and prevention of epithelial destruction
FI854634A0 (fi) * 1985-11-22 1985-11-22 Labsystems Oy Foerfarande foer bestaemning av proteolytisk aktivitet.
US5180583A (en) * 1985-11-26 1993-01-19 Hedner Ulla K E Method for the treatment of bleeding disorders
CA1297791C (en) * 1985-12-16 1992-03-24 Warren Douglas Sheffield Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator
US4889722A (en) * 1985-12-16 1989-12-26 Ethicon, Inc. Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator
DK475386D0 (da) * 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
FR2618784B1 (fr) * 1987-07-30 1990-04-06 Lille Transfusion Sanguine Concentre de proteines coagulables par la thrombine, son procede d'obtention et son utilisation a titre de colle biologique
US5260420A (en) * 1987-07-30 1993-11-09 Centre Regional De Transfusion Sanguine De Lille Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
JP2526073B2 (ja) * 1987-10-06 1996-08-21 株式会社ミドリ十字 異常破水治療剤
JP2678193B2 (ja) * 1988-03-31 1997-11-17 財団法人化学及血清療法研究所 ヒト血漿由来血液凝固第ｘ▲ｉｉｉ▼因子の製造方法
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
US4973466A (en) * 1988-06-21 1990-11-27 Chiron Ophthalmics, Inc. Wound-healing dressings and methods
US5226877A (en) * 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
WO1991001711A1 (en) * 1989-08-10 1991-02-21 W.L. Gore & Associates, Inc. A medical dispensing system for tissue adhesive components
US5599558A (en) * 1989-09-15 1997-02-04 Curative Technologies, Inc. Selecting amounts of platelet releasate for efficacious treatment of tissue
US5219328A (en) * 1990-01-03 1993-06-15 Cryolife, Inc. Fibrin sealant delivery method
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
US5030215A (en) * 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5644032A (en) * 1990-08-06 1997-07-01 Fibrin Corporation Process for producing fibrinogen concentrates
US5420250A (en) * 1990-08-06 1995-05-30 Fibrin Corporation Phase transfer process for producing native plasma protein concentrates
AU667188B2 (en) * 1990-11-27 1996-03-14 American National Red Cross, The Tissue sealant and growth factor containing compositions that promote accelerated wound healing
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US7229959B1 (en) 1990-11-27 2007-06-12 The American National Red Cross Supplemented fibrin matrix delivery systems
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
AU1461592A (en) * 1991-02-07 1992-09-07 Fibratek, Inc. Fibrinogen based adhesive
US6613324B1 (en) * 1991-02-28 2003-09-02 Bristol-Myers Squibb Company Adhesive for the gluing of biological tissues
DK83092D0 (da) * 1992-06-24 1992-06-24 Unes As Fremgangsmaade til udvinding af thrombin
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
KR100302935B1 (ko) * 1993-03-30 2001-11-30 바트 루디거 사람혈액응고인자xiii과아프로티닌을포함하는약제학적조성물
US5795780A (en) * 1993-06-23 1998-08-18 Bristol-Myers Squibb Company Method of use of autologous thrombin blood fraction in a cell culture with keratinocytes
US6057287A (en) * 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US5639940A (en) 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
USRE38827E1 (en) 1994-07-27 2005-10-11 3M Innovative Properties Company Adhesive sealant composition
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
US5585007A (en) * 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US5643192A (en) * 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
AU6169896A (en) * 1995-06-07 1996-12-30 American National Red Cross, The Supplemented and unsupplemented tissue sealants, methods of their production and use
DE19521324C1 (de) * 1995-06-12 1996-10-31 Immuno Ag Gewebeklebstoff und Verwendung desselben als Hämostyptikum
US5948427A (en) * 1996-04-25 1999-09-07 Point Medical Corporation Microparticulate surgical adhesive
WO2000062828A1 (en) 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
DE19617369A1 (de) * 1996-04-30 1997-11-06 Immuno Ag Lagerstabile Fibrinogen-Präparate
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
GB2318732A (en) * 1996-11-01 1998-05-06 Johnson & Johnson Medical Wound healing compositions containing alpha-1-antitrypsin
US5844087A (en) 1996-11-05 1998-12-01 Bayer Corporation Method and device for delivering fibrin glue
US6121232A (en) * 1997-01-31 2000-09-19 Omrix Biopharmaceuticals Sa Stabilized mixture comprising fibrinogen
US7745106B2 (en) * 1997-06-24 2010-06-29 Cascade Medical Enterprises, Llc Methods and devices for separating liquid components
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
AT406120B (de) 1997-08-28 2000-02-25 Immuno Ag Gewebekleber
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
US6884230B1 (en) 1998-03-09 2005-04-26 Baxter International Inc. Dispensing head for a tissue sealant applicator and process of use
US6524568B2 (en) * 1998-06-22 2003-02-25 Cytomedix, Inc. Enriched platelet wound healant
AU2763099A (en) 1998-06-22 2000-01-10 Charles E. Worden Enriched platelet wound healant
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
US6921380B1 (en) 1998-10-01 2005-07-26 Baxter International Inc. Component mixing catheter
CA2350628A1 (en) * 1998-11-12 2000-05-18 Polymer Biosciences, Inc. Hemostatic polymer useful for rapid blood coagulation and hemostasis
AT500670A1 (de) * 1999-05-19 2006-02-15 Bio & Bio Licensing Sa Arzneimittel zur lokalen anwendung
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
US6463335B1 (en) 1999-10-04 2002-10-08 Medtronic, Inc. Temporary medical electrical lead having electrode mounting pad with biodegradable adhesive
ES2327208T3 (es) * 1999-12-23 2009-10-27 Csl Limited Separacion de fibrinogeno de proteasas de plasma.
US20030209612A1 (en) * 2000-07-17 2003-11-13 Kevin Hahnen Spray head for applying a multi-component mixture
US7326412B2 (en) * 2000-10-13 2008-02-05 Baxter International Inc. Fibrinogen plus a non-plasmin-acting fibrinolysis inhibitor for the reduction or prevention of adhesion formation
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
US20030040480A1 (en) * 2001-07-20 2003-02-27 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
CN1599616A (zh) * 2001-10-03 2005-03-23 克里斯托弗·J·伍尔弗顿 贮存稳定的人纤维蛋白原溶液
WO2003047530A2 (en) * 2001-12-04 2003-06-12 Woolverton Christopher J Storage-stable fibrin sealant
MXPA04006438A (es) * 2001-12-31 2005-06-08 Ares Lab Llc Composiciones hemostaticas y metodos para el control de sangrado.
US20030224994A1 (en) * 2002-04-05 2003-12-04 Newton Colin John Storage stable liquid sealer protein complex
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
DE10392686T5 (de) 2002-05-24 2005-07-07 Biomet Mfg. Corp., Warsaw Vorrichtung und Verfahren zum Trennen und Konzentrieren von Flüssigkeiten, welche mehrere Komponenten enthalten
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
ES2372978T3 (es) 2002-06-07 2012-01-30 Dyax Corp. Polipéptido con dominio de kunitz modificado.
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
HUE042899T2 (hu) * 2002-08-28 2019-07-29 Dyax Corp Eljárás szervek és szövetek tartósítására
CN1327905C (zh) 2002-09-10 2007-07-25 美国国家红十字会 止血敷料
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
WO2006021584A2 (en) * 2004-08-27 2006-03-02 Novo Nordisk Health Care Ag Purification of factor xiii polypeptides from biological materials
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
AU2005308830B2 (en) * 2004-11-23 2012-01-19 Zymogenetics, Inc. Purification of recombinant human factor XIII
WO2006086201A2 (en) 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
JP4961354B2 (ja) 2005-02-07 2012-06-27 ハヌマン リミテッド ライアビリティ カンパニー 多血小板血漿濃縮装置および方法
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
WO2006102488A1 (en) * 2005-03-22 2006-09-28 Cascade Medical Enterprises, Llc Systems and methods of producing membranes
US20070014780A1 (en) * 2005-07-13 2007-01-18 Statseal Storage-stable human fibrinogen solutions
US20070248653A1 (en) * 2006-04-20 2007-10-25 Cochrum Kent C Hemostatic compositions and methods for controlling bleeding
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8430813B2 (en) * 2006-05-26 2013-04-30 Depuy Spine, Inc. Illuminated surgical access system including a surgical access device and integrated light emitter
AU2007267338B2 (en) 2006-05-31 2013-04-04 Baxter Healthcare S.A. Method for directed cell in-growth and controlled tissue regeneration in spinal surgery
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
KR20090038025A (ko) 2006-08-02 2009-04-17 코리오닉스 조직 보강 및 반흔 형성에 특히 유용한 이식용 제제
WO2008019127A2 (en) * 2006-08-04 2008-02-14 Stb Lifesaving Technologies, Inc. Solid dressing for treating wounded tissue
GB0623607D0 (en) * 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
US7806276B2 (en) 2007-04-12 2010-10-05 Hanuman, Llc Buoy suspension fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US20110034954A1 (en) * 2007-04-13 2011-02-10 Pacesetter, Inc. Sutureless reinforcement for and method of treating a myocardial infarction
WO2009020612A1 (en) * 2007-08-06 2009-02-12 Stb Lifesaving Technologies, Inc. Methods and dressing for sealing internal injuries
EP2034010A1 (en) 2007-08-30 2009-03-11 Omrix Biopharmaceuticals Ltd. Compositions suitable for repair and/or treatment of injured spinal tissue
KR20100091994A (ko) 2007-10-30 2010-08-19 백스터 인터내셔널 인코포레이티드 내장 또는 벽측 결손 치료용 재생 생기능성 콜라겐 생매트릭스의 용도
EP2620139B1 (en) 2008-02-27 2016-07-20 Biomet Biologics, LLC Interleukin-1 receptor antagonist rich solutions
WO2009111338A1 (en) * 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
EP2259803B2 (en) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
JP5292025B2 (ja) * 2008-09-09 2013-09-18 一般財団法人化学及血清療法研究所 カルボン酸含有生体組織接着剤及びその調製方法
US9566364B2 (en) 2008-12-11 2017-02-14 Baxter International Inc. Preparations based on fibrinogen and sulfated polysaccharides
US8637454B2 (en) * 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9433700B2 (en) 2009-04-27 2016-09-06 Medibeacon Inc. Tissue sealant compositions, vascular closure devices, and uses thereof
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
DK2442835T3 (en) 2009-06-16 2015-03-16 Baxter Int Styptic sponge
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9271925B2 (en) 2013-03-11 2016-03-01 Bioinspire Technologies, Inc. Multi-layer biodegradable device having adjustable drug release profile
EP2477617B1 (en) 2009-09-18 2018-01-31 Bioinspire Technologies Inc. Free-standing biodegradable patch
AU2010339045B2 (en) 2009-12-16 2014-06-05 Baxter Healthcare S.A. Hemostatic sponge
PT2521568T (pt) 2010-01-06 2018-10-26 Dyax Corp Proteínas de ligação à calicreína plasmática
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
KR101957625B1 (ko) 2010-06-01 2019-03-12 백스터 인터내셔널 인코포레이티드 건조 및 안정한 지혈 조성물의 제조 방법
MX352875B (es) 2010-06-01 2017-12-13 Baxter Healthcare Sa Proceso para elaborar composiciones hemostaticas secas y estables.
WO2011151384A1 (en) 2010-06-01 2011-12-08 Baxter International Inc. Process for making dry and stable hemostatic compositions
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
US20140287044A1 (en) * 2011-03-04 2014-09-25 Rare Antibody Antigen Supply, Inc. Fibrin sealant (fibringluraas) consisting of a kit of lyophilized or frozen high concentrate fribinogen
ES2938566T3 (es) 2011-10-11 2023-04-12 Baxter Int Composiciones hemostaticas
CA2851321C (en) 2011-10-11 2020-07-07 Baxter International Inc. Hemostatic compositions
ES2553702T3 (es) 2011-10-27 2015-12-11 Baxter International Inc Composiciones hemostáticas
US11109849B2 (en) 2012-03-06 2021-09-07 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
BR112014030962A2 (pt) 2012-06-12 2017-06-27 Ferrosan Medical Devices As métodos para preparação e para reconstituição de uma composição seca adequada para uso em hemostase e cicatrização de feridas, e, kit hemostático
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9724078B2 (en) 2013-06-21 2017-08-08 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
KR101567053B1 (ko) 2013-09-30 2015-11-09 한국원자력의학원 방사선 피폭에 의한 간 손상 예측용 바이오마커 및 그 예측방법
CN105828844B (zh) 2013-12-11 2019-09-27 弗罗桑医疗设备公司 包含挤出增强剂的干组合物
IL295414A (en) 2014-03-27 2022-10-01 Takeda Pharmaceuticals Co Compositions and methods for treating macular edema as a result of diabetes
CN106999621B (zh) 2014-10-13 2020-07-03 弗罗桑医疗设备公司 用于止血和伤口愈合的干组合物
BR112017013565B1 (pt) 2014-12-24 2021-12-28 Ferrosan Medical Devices A/S Seringa para retenção e mistura de primeira e segunda substâncias
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
KR20180094028A (ko) 2015-12-11 2018-08-22 다이액스 코포레이션 혈장 칼리크레인 저해제 및 유전성 혈관부종 발작을 치료하기 위한 이의 용도
CA3097819A1 (en) 2018-05-09 2019-11-14 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
WO2023129802A1 (en) 2021-12-30 2023-07-06 Baxter International Inc. Fibrinogen and thrombin solutions for a fibrin sealant and fibrin sealant kit

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422407A1 (fr) * 1978-04-12 1979-11-09 Unitika Ltd Matiere cicatrisante facilitant la cicatrisation des blessures

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422407A1 (fr) * 1978-04-12 1979-11-09 Unitika Ltd Matiere cicatrisante facilitant la cicatrisation des blessures

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253198A1 (de) * 1986-07-05 1988-01-20 BEHRINGWERKE Aktiengesellschaft Einkomponenten-Gewebekleber sowie Verfahren zu seiner Herstellung
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6841150B2 (en) 1999-08-19 2005-01-11 Artecal, Sciences, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US7033587B2 (en) 1999-08-19 2006-04-25 Artecel Sciences, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US7078232B2 (en) 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US8048673B2 (en) 1999-08-19 2011-11-01 Artecel Sciences, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US8911994B2 (en) 1999-08-19 2014-12-16 Artecel Sciences Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US8598319B2 (en) 2005-06-29 2013-12-03 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Process for separating proteins fibrinogen, factor XIII and biological glue from a solubilized plasma fraction and for preparing lyophilised concentrates of said proteins
EP2772499A1 (fr) 2005-06-29 2014-09-03 Laboratoire Français du Fractionnement et des Biotechnologies Separation de proteines plasmatiques
US8383104B2 (en) 2005-12-16 2013-02-26 Laboratoire Francais Du Fractionnement Et Des Biotechnologies S.A. Thrombin-free biological adhesive and use thereof as a medicament
EP3075387A1 (fr) 2005-12-16 2016-10-05 Laboratoire Français du Fractionnement et des Biotechnologies Colle biologique exempte de thrombine et son utilisation comme medicament
WO2011061705A1 (fr) 2009-11-18 2011-05-26 Lfb Biomedicaments Procede de traitement du plasma sanguin comprenant une etape de lavage par dispersion

Also Published As

Publication number Publication date
ATA119079A (de) 1980-04-15
NL190748B (nl) 1994-03-01
FR2448901B1 ( ) 1984-09-07
AR226837A1 (es) 1982-08-31
AR222209A1 (es) 1981-04-30
DE3002933A1 (de) 1980-08-28
SE453800B (sv) 1988-03-07
SE8000470L (sv) 1980-08-16
JPS55110557A (en) 1980-08-26
BE881467A (fr) 1980-05-16
IT8019911A0 (it) 1980-02-14
GB2042556A (en) 1980-09-24
IT1141212B (it) 1986-10-01
GB2042556B (en) 1983-04-13
NL8000936A (nl) 1980-08-19
US4377572A (en) 1983-03-22
JPS6340547B2 ( ) 1988-08-11
DE3002933C2 (de) 1984-01-26
ES488431A0 (es) 1980-12-16
US4298598A (en) 1981-11-03
AT359653B (de) 1980-11-25
SE8902376D0 (sv) 1989-06-30
CH649925A5 (de) 1985-06-28
DK65680A (da) 1980-08-16
CA1119516A (en) 1982-03-09
DK151611B (da) 1987-12-21
SE463350B (sv) 1990-11-12
ES8101382A1 (es) 1980-12-16

Similar Documents

Publication Publication Date Title
FR2448901A1 (fr) Colle servant a reunir des tissus humains ou d'animaux, procede permettant sa fabrication et applications d'une telle colle
FR2448900A1 (fr) Colle servant a reunir des tissus humains ou d'animaux, procede permettant sa fabrication et applications d'une telle colle
RU2130946C1 (ru) Способ получения биологического клея, изготовленного из концентрированных коагулирующих факторов посредством "высаливания"
US5260420A (en) Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
US5290918A (en) Process for the obtention of a biological adhesive made of concentrated coagulation factors by acidic precipitation
Sgouris et al. The preparation of human fibrinolysin (plasmin)
CA2437064C (en) Storage-stable, liquid fibrinogen formulation
US4552760A (en) Method for stabilizing tissue plasminogen activator and a stable aqueous solution or powder containing the same
JP2787317B2 (ja) トロンビン凝固性蛋白質の濃縮物、その製造方法及びその治療的用途
AT408614B (de) Thrombosemittel
EP0041173B2 (en) Blood-coagulation-promoting products and methods of preparing them
JPS6236502B2 ( )
DK167738B1 (da) Fremgangsmaade til fremstilling af en oploesning med hoej specifik rumfangsaktivitet af et protein med vaevs-plasminogenaktivator(t-pa)-aktivitet, oploesning der indeholder protein med t-pa-aktivitet, og anvendelsen af oploesningen inden for human- og veterinaermedicinen
US4837022A (en) Composition containing tissue plasminogen activator
US3234106A (en) Soluble, purified profibrinolysin and fibrinolysin and method of producing same
EP0624642A1 (en) Novel thrombolytic agent, process for preparing same and its use for the preparation of a thrombi dissolving medicament
EP0151996B1 (en) Process for the preparation of a double-chain plasminogen activator
IE902766A1 (en) Pasteurized glue for joining human or animal tissues
FR2664165A1 (fr) Composition pour stabiliser le plasma sanguin en cours de pasteurisation.
JPH0725696B2 (ja) プラスミノ−ゲンの安定化方法
EP0326013A3 (en) Novel proteins derived from human alpha2-plasmin inhibitor or proteins similar thereto
RU94036434A (ru) Способ получения концентрата фибриногена
de Lille llllllllllllllllllllllIlllllwglllllllllIllllllllllllllllllllllllllllllll
JPS6348220A (ja) 血液凝固第９因子複合体の製造法

Legal Events

Date Code Title Description
CA Change of address
CD Change of name or company name
CL Concession to grant licences
CD Change of name or company name