FR2446823B1 - - Google Patents

Info

Publication number
FR2446823B1
FR2446823B1 FR7900971A FR7900971A FR2446823B1 FR 2446823 B1 FR2446823 B1 FR 2446823B1 FR 7900971 A FR7900971 A FR 7900971A FR 7900971 A FR7900971 A FR 7900971A FR 2446823 B1 FR2446823 B1 FR 2446823B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7900971A
Other languages
French (fr)
Other versions
FR2446823A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7900971A priority Critical patent/FR2446823A1/fr
Priority to FR7931656A priority patent/FR2476088A2/fr
Priority to SE8000068A priority patent/SE444941B/sv
Priority to GR60908A priority patent/GR66499B/el
Priority to US06/110,067 priority patent/US4471120A/en
Priority to CA343,219A priority patent/CA1130286A/en
Priority to CH111/80A priority patent/CH647520A5/fr
Priority to IT19071/80A priority patent/IT1148801B/it
Priority to ZA00800160A priority patent/ZA80160B/xx
Priority to GB8001037A priority patent/GB2042522B/en
Priority to GB8028343A priority patent/GB2055374B/en
Priority to BE0/198955A priority patent/BE881134A/fr
Priority to LU82083A priority patent/LU82083A1/fr
Priority to AU54610/80A priority patent/AU542537B2/en
Priority to MX10153780U priority patent/MX6529E/es
Priority to ES487721A priority patent/ES487721A1/es
Priority to NL8000277A priority patent/NL8000277A/nl
Priority to JP55003433A priority patent/JPS6059915B2/ja
Priority to DE19803001328 priority patent/DE3001328A1/de
Priority to DE3049963A priority patent/DE3049963C2/de
Priority to SE8005674A priority patent/SE431984B/sv
Publication of FR2446823A1 publication Critical patent/FR2446823A1/fr
Priority to CH622080A priority patent/CH646969A5/fr
Priority to US06/186,100 priority patent/US4424358A/en
Priority to IT8024713A priority patent/IT1235424B/it
Priority to NL8005774A priority patent/NL8005774A/nl
Priority to US06/254,684 priority patent/US4329466A/en
Priority to US06/254,683 priority patent/US4321378A/en
Priority to JP6772381A priority patent/JPS56164187A/ja
Priority to US06/399,392 priority patent/US4536580A/en
Priority to CA000409952A priority patent/CA1160227A/en
Priority to JP58122438A priority patent/JPS5976084A/ja
Application granted granted Critical
Publication of FR2446823B1 publication Critical patent/FR2446823B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7900971A 1979-01-16 1979-01-16 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique Granted FR2446823A1 (fr)

Priority Applications (31)

Application Number Priority Date Filing Date Title
FR7900971A FR2446823A1 (fr) 1979-01-16 1979-01-16 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
FR7931656A FR2476088A2 (fr) 1979-01-16 1979-12-26 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
SE8000068A SE444941B (sv) 1979-01-16 1980-01-04 Derivat av nor-tropan och farmaceutisk komposition derav
GR60908A GR66499B (no) 1979-01-16 1980-01-05
US06/110,067 US4471120A (en) 1979-01-16 1980-01-07 Nor-tropane derivatives
CH111/80A CH647520A5 (fr) 1979-01-16 1980-01-08 Derives du nortropane, leur procede de preparation et composition pharmaceutique les contenant.
CA343,219A CA1130286A (en) 1979-01-16 1980-01-08 Derivates of nor-tropane, a process for preparing same and their application in therapeutics
IT19071/80A IT1148801B (it) 1979-01-16 1980-01-08 Derivati del nor-tropano, loro procedimento di preparazione e loro applicazione terapeutica
ZA00800160A ZA80160B (en) 1979-01-16 1980-01-10 Novel nor-tropane derivatives,a process for preparing same and their application in therapeutics
GB8001037A GB2042522B (en) 1979-01-16 1980-01-11 Nor-tropane derivatives a process for preparing same and their application in therapeutics
GB8028343A GB2055374B (en) 1979-01-16 1980-01-11 -amino-3 nor-tropane derivatives
BE0/198955A BE881134A (fr) 1979-01-16 1980-01-14 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
LU82083A LU82083A1 (fr) 1979-01-16 1980-01-14 Nouveaux derives du nor-tropane,leur procede de preparation et leur application en therapeutique
MX10153780U MX6529E (es) 1979-01-16 1980-01-15 Procedimiento para preparar derivados del nor-tropano
ES487721A ES487721A1 (es) 1979-01-16 1980-01-15 Procedimiento de preparacion de nuevos derivados del nor- tropano
AU54610/80A AU542537B2 (en) 1979-01-16 1980-01-15 Nor-tropane derivatives
NL8000277A NL8000277A (nl) 1979-01-16 1980-01-16 Nieuwe nor-tropaanverbindingen alsmede werkwijze ter bereiding en therapeutische toepassing van deze verbindingen.
JP55003433A JPS6059915B2 (ja) 1979-01-16 1980-01-16 新規なノル−トロパン誘導体、その製法及び用途
DE19803001328 DE3001328A1 (de) 1979-01-16 1980-01-16 Neue nortropan-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel
DE3049963A DE3049963C2 (de) 1979-01-16 1980-01-16 3-ß-Amino-nortropan-Derivate und Verfahren zu ihrer Herstellung
SE8005674A SE431984B (sv) 1979-01-16 1980-08-12 Derivat av 3-beta-amiro-nortropan som mellanprodukter for framstellning av nortropanderivat
CH622080A CH646969A5 (fr) 1979-01-16 1980-08-18 Derives du beta-amino-3 nor-tropane.
US06/186,100 US4424358A (en) 1979-01-16 1980-09-11 β-3-Amino nor-tropane compounds
IT8024713A IT1235424B (it) 1979-01-16 1980-09-17 Derivati del beta-3-ammino-nortropano
NL8005774A NL8005774A (nl) 1979-01-16 1980-10-20 Nieuwe 3-beta-amino-nor-tropaanverbindingen.
US06/254,684 US4329466A (en) 1979-01-16 1981-04-16 Certain nor-tropan-8-amine-3-aryl or heteroaryl derivatives
US06/254,683 US4321378A (en) 1979-01-16 1981-04-16 8-(5-Pyrimidinecarboxamide)nor-tropane derivatives
JP6772381A JPS56164187A (en) 1979-01-16 1981-05-07 Novel beta-amino-3-nor tropane derivative
US06/399,392 US4536580A (en) 1979-01-16 1982-07-19 4-Amino-5-bromo-2-methoxy-N-[8-(benzyl)]-8-azabicyclo[3.2.1]-3-YL-benzamide or a pharmacologically acceptable acid addition salt thereof
CA000409952A CA1160227A (en) 1979-01-16 1982-08-23 DERIVATIVES OF .beta.-3-AMINO-N-NOR-TROPANES
JP58122438A JPS5976084A (ja) 1979-01-16 1983-07-07 新規なノル−トロパン誘導体、その製法及び用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7900971A FR2446823A1 (fr) 1979-01-16 1979-01-16 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2446823A1 FR2446823A1 (fr) 1980-08-14
FR2446823B1 true FR2446823B1 (no) 1983-10-21

Family

ID=9220797

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7900971A Granted FR2446823A1 (fr) 1979-01-16 1979-01-16 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique

Country Status (3)

Country Link
JP (3) JPS6059915B2 (no)
FR (1) FR2446823A1 (no)
ZA (1) ZA80160B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
EP0069481A1 (en) * 1981-06-17 1983-01-12 Beecham Group Plc Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
DE3268378D1 (en) * 1981-06-17 1986-02-20 Beecham Group Plc Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions
EP0068700A1 (en) * 1981-06-29 1983-01-05 Beecham Group Plc Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them
EP0069482A1 (en) * 1981-06-29 1983-01-12 Beecham Group Plc Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
AU2009234140B2 (en) 2008-04-11 2013-04-11 Janssen Pharmaceutica Nv Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase
MX2011012190A (es) 2009-05-14 2011-12-08 Janssen Pharmaceutica Nv Compuestos con dos porciones de heteroarilo biciclico fusionado como moduladores de la leucotrieno a4 hidrolasa.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1162129A (fr) * 1954-10-20 1958-09-09 Sandoz Ag Dérivés amidés du tropane et leur préparation
JPS5592384A (en) * 1978-12-30 1980-07-12 Beecham Group Ltd Compound having pharmacological activity
JPH01112779A (ja) * 1987-10-27 1989-05-01 Oki Electric Ind Co Ltd 定電圧ダイオード及びその製造方法

Also Published As

Publication number Publication date
JPS56164187A (en) 1981-12-17
FR2446823A1 (fr) 1980-08-14
ZA80160B (en) 1981-01-28
JPS5976084A (ja) 1984-04-28
JPS6059915B2 (ja) 1985-12-27
JPS55108871A (en) 1980-08-21

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Legal Events

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TP Transmission of property