FR2444681A1 - Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments - Google Patents

Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments

Info

Publication number
FR2444681A1
FR2444681A1 FR7930829A FR7930829A FR2444681A1 FR 2444681 A1 FR2444681 A1 FR 2444681A1 FR 7930829 A FR7930829 A FR 7930829A FR 7930829 A FR7930829 A FR 7930829A FR 2444681 A1 FR2444681 A1 FR 2444681A1
Authority
FR
France
Prior art keywords
novel
preparation
dihydropyridines
medicaments
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7930829A
Other languages
English (en)
French (fr)
Other versions
FR2444681B1 (sv
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2444681A1 publication Critical patent/FR2444681A1/fr
Application granted granted Critical
Publication of FR2444681B1 publication Critical patent/FR2444681B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR7930829A 1978-12-18 1979-12-17 Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments Granted FR2444681A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1283578A CH639659A5 (de) 1978-12-18 1978-12-18 Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.

Publications (2)

Publication Number Publication Date
FR2444681A1 true FR2444681A1 (fr) 1980-07-18
FR2444681B1 FR2444681B1 (sv) 1982-10-29

Family

ID=4386824

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7930829A Granted FR2444681A1 (fr) 1978-12-18 1979-12-17 Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments

Country Status (18)

Country Link
JP (1) JPS5583783A (sv)
AU (1) AU536055B2 (sv)
BE (1) BE880591A (sv)
CH (1) CH639659A5 (sv)
CY (1) CY1321A (sv)
DE (1) DE2949491A1 (sv)
FR (1) FR2444681A1 (sv)
GB (2) GB2037766B (sv)
HK (1) HK16086A (sv)
IE (1) IE49496B1 (sv)
IT (1) IT1164097B (sv)
KE (1) KE3593A (sv)
MY (1) MY8500130A (sv)
NL (2) NL193066C (sv)
NZ (1) NZ192422A (sv)
SE (1) SE445219B (sv)
SG (1) SG97585G (sv)
ZA (1) ZA796842B (sv)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490092A1 (fr) * 1980-09-18 1982-03-19 Sandoz Sa Nouvelles compositions pharmaceutiques a base d'un derive de la 1,4-dihydropyridine

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
DE3269219D1 (en) * 1981-11-17 1986-03-27 Fisons Plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
IL68975A (en) * 1982-06-15 1987-01-30 Sandoz Ag 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
JPS5978186A (ja) * 1982-10-27 1984-05-04 Yoshitomi Pharmaceut Ind Ltd 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
NL194389C (nl) * 1984-06-14 2002-03-04 Novartis Ag Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager.
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
HU197201B (en) * 1985-10-01 1989-03-28 Sandoz Ag Process for producing oral pharmaceutical compositions of controlled solubility of the active components
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
GB8626217D0 (en) * 1986-11-03 1986-12-03 Sandoz Ltd Pharmaceutical compositions
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
KR940003492B1 (ko) * 1988-10-27 1994-04-23 주식회사 유한양행 1,4-디하이드로피리딘유도체 및 그의 제조방법
DE4222770A1 (de) * 1992-07-10 1994-01-13 Bayer Ag Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
WO2005023787A1 (en) * 2003-09-10 2005-03-17 Shasun Chemicals And Drugs Limited Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde
CN103613584B (zh) * 2013-11-27 2016-04-27 沈阳药科大学 一种伊拉地平合成产物后处理的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000150A1 (en) * 1977-06-20 1979-01-10 Sandoz Ag Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2616991A1 (de) * 1976-04-17 1977-10-27 Bayer Ag Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS5373327A (en) * 1976-12-13 1978-06-29 Matsushita Electric Ind Co Ltd Power source system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000150A1 (en) * 1977-06-20 1979-01-10 Sandoz Ag Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490092A1 (fr) * 1980-09-18 1982-03-19 Sandoz Sa Nouvelles compositions pharmaceutiques a base d'un derive de la 1,4-dihydropyridine

Also Published As

Publication number Publication date
SG97585G (en) 1986-07-18
GB2037766B (en) 1983-02-16
NL193066C (nl) 1998-09-08
AU536055B2 (en) 1984-04-19
HK16086A (en) 1986-03-14
GB2103203A (en) 1983-02-16
CY1321A (en) 1986-06-27
BE880591A (fr) 1980-06-13
NZ192422A (en) 1982-09-14
NL7909024A (nl) 1980-06-20
MY8500130A (en) 1985-12-31
FR2444681B1 (sv) 1982-10-29
GB2037766A (en) 1980-07-16
AU5389679A (en) 1980-06-26
ZA796842B (en) 1981-07-29
SE7910188L (sv) 1980-06-19
IT1164097B (it) 1987-04-08
CH639659A5 (de) 1983-11-30
SE445219B (sv) 1986-06-09
JPS5583783A (en) 1980-06-24
GB2103203B (en) 1983-06-08
IT7951095A0 (it) 1979-12-14
NL990014I1 (nl) 1999-07-01
IE792445L (en) 1980-06-18
JPH0369910B2 (sv) 1991-11-05
DE2949491A1 (de) 1980-06-26
IE49496B1 (en) 1985-10-16
DE2949491C2 (sv) 1988-10-27
NL193066B (nl) 1998-05-06
KE3593A (en) 1986-02-07

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0169, 920507

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0169, 791217

CL Concession to grant licences
TP Transmission of property