FR2392986B1 - - Google Patents

Info

Publication number
FR2392986B1
FR2392986B1 FR7816545A FR7816545A FR2392986B1 FR 2392986 B1 FR2392986 B1 FR 2392986B1 FR 7816545 A FR7816545 A FR 7816545A FR 7816545 A FR7816545 A FR 7816545A FR 2392986 B1 FR2392986 B1 FR 2392986B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7816545A
Other versions
FR2392986A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Original Assignee
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp filed Critical Pfizer Corp
Publication of FR2392986A1 publication Critical patent/FR2392986A1/fr
Application granted granted Critical
Publication of FR2392986B1 publication Critical patent/FR2392986B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7816545A 1977-06-03 1978-06-02 Nouveaux composes de phtalazine et composition pharmaceutique les contenant Granted FR2392986A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (2)

Publication Number Publication Date
FR2392986A1 FR2392986A1 (fr) 1978-12-29
FR2392986B1 true FR2392986B1 (fr) 1982-07-16

Family

ID=10198020

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7816545A Granted FR2392986A1 (fr) 1977-06-03 1978-06-02 Nouveaux composes de phtalazine et composition pharmaceutique les contenant

Country Status (29)

Country Link
US (1) US4289772A (fr)
JP (1) JPS5416488A (fr)
AR (2) AR222013A1 (fr)
AT (2) AT362792B (fr)
AU (1) AU505373B1 (fr)
BE (1) BE867727A (fr)
CA (1) CA1111850A (fr)
DD (1) DD137355A5 (fr)
DE (1) DE2824064A1 (fr)
DK (1) DK248078A (fr)
EG (1) EG13527A (fr)
ES (4) ES470470A1 (fr)
FI (1) FI781753A (fr)
FR (1) FR2392986A1 (fr)
GB (1) GB2000136B (fr)
GR (1) GR74402B (fr)
HU (1) HU179745B (fr)
IL (1) IL54842A (fr)
IN (3) IN148482B (fr)
IT (1) IT1094944B (fr)
LU (1) LU79761A1 (fr)
NL (1) NL7806016A (fr)
NO (1) NO781935L (fr)
NZ (1) NZ187453A (fr)
PL (3) PL116437B1 (fr)
PT (1) PT68126A (fr)
SE (1) SE7806519L (fr)
SU (2) SU856383A3 (fr)
ZA (1) ZA783183B (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
GR73576B (fr) * 1980-03-01 1984-03-20 Wyeth John & Brother Ltd
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
EP0621267A1 (fr) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Dérivés de spiropipéridine et leur utilisation comme fongicides
AU5772196A (en) * 1995-05-19 1996-11-29 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
AU722710B2 (en) * 1996-08-20 2000-08-10 Eisai Co. Ltd. Remedies for erectile dysfunction containing fused pyridazine compounds
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
AU2003259891A1 (en) * 2002-08-16 2004-03-19 Janssen Pharmaceutica N.V. Piperidinyl compounds that selectively bind integrins
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
EP2275095A3 (fr) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenese par modulation des recepteurs muscariniques
EP2258358A3 (fr) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenèse avec un inhibiteur de l'acetylcholinestérase
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
CA2625210A1 (fr) 2005-10-31 2007-05-10 Braincells, Inc. Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
BRPI0707223A2 (pt) * 2006-01-27 2011-04-26 Pfizer Prod Inc compostos de derivados de aminoftalazina
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US8247442B2 (en) 2006-03-29 2012-08-21 Purdue Pharma L.P. Benzenesulfonamide compounds and their use
WO2007118854A1 (fr) 2006-04-13 2007-10-25 Euro-Celtique S.A. Composés à base de benzènesulfonamide et leur utilisation
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
EP1900731A1 (fr) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amides comme modulateurs du récepteur EP2
EP1903037A1 (fr) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft Dérivés de 1-[(hétéro)aryl]-3-[hétéroaryl-pipéridine-4-yl]thiourée en tant que modulateurs de récepteurs EP2
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
CN101778837A (zh) 2007-08-07 2010-07-14 弗·哈夫曼-拉罗切有限公司 作为nk3受体拮抗剂的吡咯烷芳基-醚
EP2190815B1 (fr) 2007-08-22 2011-08-10 F. Hoffmann-La Roche AG Pyrrolidine aryl-éther en tant qu'antagonistes des récepteurs de nk3
KR101174980B1 (ko) * 2007-09-14 2012-08-17 에프. 호프만-라 로슈 아게 Ｎｋ３ 수용체 길항제로서의 피페리딘 유도체
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
WO2010099217A1 (fr) 2009-02-25 2010-09-02 Braincells, Inc. Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine
AR077014A1 (es) 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
WO2013106547A1 (fr) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
HU179745B (en) 1982-12-28
US4289772A (en) 1981-09-15
ES478199A1 (es) 1980-01-16
FI781753A (fi) 1978-12-04
NO781935L (no) 1978-12-05
AR223999A1 (es) 1981-10-15
ES478201A1 (es) 1980-02-01
ZA783183B (en) 1979-06-27
PL207337A1 (pl) 1979-06-04
ES478200A1 (es) 1980-01-01
ATA400878A (de) 1980-11-15
DE2824064A1 (de) 1978-12-14
AR222013A1 (es) 1981-04-15
DD137355A5 (de) 1979-08-29
IT1094944B (it) 1985-08-10
DK248078A (da) 1978-12-04
PL116437B1 (en) 1981-06-30
BE867727A (fr) 1978-12-01
GB2000136A (en) 1979-01-04
IN148482B (fr) 1981-03-07
SE7806519L (sv) 1978-12-04
NL7806016A (nl) 1978-12-05
JPS5538351B2 (fr) 1980-10-03
JPS5416488A (en) 1979-02-07
PT68126A (en) 1978-07-01
PL116420B1 (en) 1981-06-30
SU856383A3 (ru) 1981-08-15
CA1111850A (fr) 1981-11-03
GR74402B (fr) 1984-06-28
AT362792B (de) 1981-06-10
PL113208B1 (en) 1980-11-29
AU505373B1 (en) 1979-11-15
IN149973B (fr) 1982-06-19
AT363096B (de) 1981-07-10
LU79761A1 (fr) 1980-01-22
IT7824106A0 (it) 1978-06-01
IN149550B (fr) 1982-01-16
FR2392986A1 (fr) 1978-12-29
SU862826A3 (ru) 1981-09-07
NZ187453A (en) 1980-12-19
IL54842A (en) 1982-01-31
ATA305080A (de) 1980-12-15
GB2000136B (en) 1982-01-06
IL54842A0 (en) 1978-08-31
EG13527A (en) 1981-12-31
ES470470A1 (es) 1979-09-01

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Legal Events

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