FR2392986B1 - - Google Patents

Info

Publication number
FR2392986B1
FR2392986B1 FR7816545A FR7816545A FR2392986B1 FR 2392986 B1 FR2392986 B1 FR 2392986B1 FR 7816545 A FR7816545 A FR 7816545A FR 7816545 A FR7816545 A FR 7816545A FR 2392986 B1 FR2392986 B1 FR 2392986B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7816545A
Other languages
French (fr)
Other versions
FR2392986A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Original Assignee
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp filed Critical Pfizer Corp
Publication of FR2392986A1 publication Critical patent/FR2392986A1/fr
Application granted granted Critical
Publication of FR2392986B1 publication Critical patent/FR2392986B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7816545A 1977-06-03 1978-06-02 Nouveaux composes de phtalazine et composition pharmaceutique les contenant Granted FR2392986A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2358277 1977-06-03

Publications (2)

Publication Number Publication Date
FR2392986A1 FR2392986A1 (fr) 1978-12-29
FR2392986B1 true FR2392986B1 (US20030186963A1-20031002-C00002.png) 1982-07-16

Family

ID=10198020

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7816545A Granted FR2392986A1 (fr) 1977-06-03 1978-06-02 Nouveaux composes de phtalazine et composition pharmaceutique les contenant

Country Status (29)

Country Link
US (1) US4289772A (US20030186963A1-20031002-C00002.png)
JP (1) JPS5416488A (US20030186963A1-20031002-C00002.png)
AR (2) AR222013A1 (US20030186963A1-20031002-C00002.png)
AT (2) AT362792B (US20030186963A1-20031002-C00002.png)
AU (1) AU505373B1 (US20030186963A1-20031002-C00002.png)
BE (1) BE867727A (US20030186963A1-20031002-C00002.png)
CA (1) CA1111850A (US20030186963A1-20031002-C00002.png)
DD (1) DD137355A5 (US20030186963A1-20031002-C00002.png)
DE (1) DE2824064A1 (US20030186963A1-20031002-C00002.png)
DK (1) DK248078A (US20030186963A1-20031002-C00002.png)
EG (1) EG13527A (US20030186963A1-20031002-C00002.png)
ES (4) ES470470A1 (US20030186963A1-20031002-C00002.png)
FI (1) FI781753A (US20030186963A1-20031002-C00002.png)
FR (1) FR2392986A1 (US20030186963A1-20031002-C00002.png)
GB (1) GB2000136B (US20030186963A1-20031002-C00002.png)
GR (1) GR74402B (US20030186963A1-20031002-C00002.png)
HU (1) HU179745B (US20030186963A1-20031002-C00002.png)
IL (1) IL54842A (US20030186963A1-20031002-C00002.png)
IN (3) IN148482B (US20030186963A1-20031002-C00002.png)
IT (1) IT1094944B (US20030186963A1-20031002-C00002.png)
LU (1) LU79761A1 (US20030186963A1-20031002-C00002.png)
NL (1) NL7806016A (US20030186963A1-20031002-C00002.png)
NO (1) NO781935L (US20030186963A1-20031002-C00002.png)
NZ (1) NZ187453A (US20030186963A1-20031002-C00002.png)
PL (3) PL116437B1 (US20030186963A1-20031002-C00002.png)
PT (1) PT68126A (US20030186963A1-20031002-C00002.png)
SE (1) SE7806519L (US20030186963A1-20031002-C00002.png)
SU (2) SU856383A3 (US20030186963A1-20031002-C00002.png)
ZA (1) ZA783183B (US20030186963A1-20031002-C00002.png)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) * 1979-03-28 1980-06-30 Pfizer Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
CA1173037A (en) * 1980-03-01 1984-08-21 John L. Archibald Piperidino ureas as antidepressants
GB8320958D0 (en) * 1983-08-03 1983-09-07 Pfizer Ltd Quinazoline cardiac stimulants
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
EP0621267A1 (en) * 1993-04-07 1994-10-26 Shell Internationale Researchmaatschappij B.V. Spiropiperidine derivatives and their use as fungicides
AU5772196A (en) * 1995-05-19 1996-11-29 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
CN1121220C (zh) * 1996-08-20 2003-09-17 卫材株式会社 稠合哒嗪系化合物的勃起机能不全症治疗剂
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
RU2333210C2 (ru) * 2002-08-16 2008-09-10 Янссен Фармацевтика Н.В. Соединения пиперидинила, селективно связывающие интегрины
US20040224986A1 (en) * 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
JP2009524637A (ja) * 2006-01-27 2009-07-02 ファイザー・プロダクツ・インク アミノフタラジン誘導体化合物
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007110449A1 (en) 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
TW200812963A (en) 2006-04-13 2008-03-16 Euro Celtique Sa Benzenesulfonamide compounds and the use thereof
US8791264B2 (en) 2006-04-13 2014-07-29 Purdue Pharma L.P. Benzenesulfonamide compounds and their use as blockers of calcium channels
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
EP1900731A1 (de) * 2006-09-07 2008-03-19 Bayer Schering Pharma Aktiengesellschaft N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
RU2010106974A (ru) 2007-08-07 2011-09-20 Ф.Хоффманн-Ля Рош Аг (Ch) Ариловые эфиры пирролидина в качестве антагонистов рецепторов nk3
ATE519738T1 (de) 2007-08-22 2011-08-15 Hoffmann La Roche Pyrrolidinarylether als nk3-rezeptorantagonisten
CA2699464A1 (en) * 2007-09-14 2009-03-19 F. Hoffmann-La Roche Ag Piperidine derivatives as nk3 receptor antagonists
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
CN113087654B (zh) * 2021-04-15 2022-12-23 苏州昊帆生物股份有限公司 哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094044A (en) * 1965-07-12 1967-12-06 Vantorex Ltd Phthalazine derivatives
GB1199768A (en) 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en) 1974-07-25 1977-01-06 Pfizer Ltd 4-substituted quinazoline cardiac stimulants

Also Published As

Publication number Publication date
IN148482B (US20030186963A1-20031002-C00002.png) 1981-03-07
US4289772A (en) 1981-09-15
SU856383A3 (ru) 1981-08-15
FI781753A (fi) 1978-12-04
IT7824106A0 (it) 1978-06-01
CA1111850A (en) 1981-11-03
JPS5538351B2 (US20030186963A1-20031002-C00002.png) 1980-10-03
IT1094944B (it) 1985-08-10
PL207337A1 (pl) 1979-06-04
GB2000136B (en) 1982-01-06
LU79761A1 (fr) 1980-01-22
PL116437B1 (en) 1981-06-30
FR2392986A1 (fr) 1978-12-29
PL116420B1 (en) 1981-06-30
DK248078A (da) 1978-12-04
GR74402B (US20030186963A1-20031002-C00002.png) 1984-06-28
ATA400878A (de) 1980-11-15
BE867727A (fr) 1978-12-01
IL54842A (en) 1982-01-31
AT362792B (de) 1981-06-10
HU179745B (en) 1982-12-28
AR223999A1 (es) 1981-10-15
JPS5416488A (en) 1979-02-07
ES478199A1 (es) 1980-01-16
NL7806016A (nl) 1978-12-05
EG13527A (en) 1981-12-31
SE7806519L (sv) 1978-12-04
PL113208B1 (en) 1980-11-29
ES478200A1 (es) 1980-01-01
ES470470A1 (es) 1979-09-01
IN149973B (US20030186963A1-20031002-C00002.png) 1982-06-19
ES478201A1 (es) 1980-02-01
ZA783183B (en) 1979-06-27
GB2000136A (en) 1979-01-04
NO781935L (no) 1978-12-05
ATA305080A (de) 1980-12-15
IL54842A0 (en) 1978-08-31
IN149550B (US20030186963A1-20031002-C00002.png) 1982-01-16
SU862826A3 (ru) 1981-09-07
PT68126A (en) 1978-07-01
DE2824064A1 (de) 1978-12-14
DD137355A5 (de) 1979-08-29
AU505373B1 (en) 1979-11-15
AT363096B (de) 1981-07-10
NZ187453A (en) 1980-12-19
AR222013A1 (es) 1981-04-15

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Legal Events

Date Code Title Description
ST Notification of lapse