FR2298318A1 - Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti - Google Patents

Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti

Info

Publication number
FR2298318A1
FR2298318A1 FR7602016A FR7602016A FR2298318A1 FR 2298318 A1 FR2298318 A1 FR 2298318A1 FR 7602016 A FR7602016 A FR 7602016A FR 7602016 A FR7602016 A FR 7602016A FR 2298318 A1 FR2298318 A1 FR 2298318A1
Authority
FR
France
Prior art keywords
acti
preparing
principle
pharmaceutical composition
liquid pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7602016A
Other languages
English (en)
French (fr)
Other versions
FR2298318B1 (OSRAM
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2298318A1 publication Critical patent/FR2298318A1/fr
Application granted granted Critical
Publication of FR2298318B1 publication Critical patent/FR2298318B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7602016A 1975-01-27 1976-01-26 Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti Granted FR2298318A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50011751A JPS5186117A (en) 1975-01-27 1975-01-27 Johoseibiryushiseizainoseiho

Publications (2)

Publication Number Publication Date
FR2298318A1 true FR2298318A1 (fr) 1976-08-20
FR2298318B1 FR2298318B1 (OSRAM) 1978-12-08

Family

ID=11786697

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7602016A Granted FR2298318A1 (fr) 1975-01-27 1976-01-26 Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti

Country Status (5)

Country Link
US (1) US4016100A (OSRAM)
JP (1) JPS5186117A (OSRAM)
DE (1) DE2601207C3 (OSRAM)
FR (1) FR2298318A1 (OSRAM)
GB (1) GB1487989A (OSRAM)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399241A1 (fr) * 1977-08-05 1979-03-02 Battelle Memorial Institute Procede de deshydratation d'une dispersion colloidale de liposomes
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
EP0004223A1 (fr) * 1978-02-24 1979-09-19 PAPAHADJOPOULOS, Demetrios P. Procédé de fabrication de capsules lipidiques renfermant un matériau biologiquement actif, produits obtenus par ce procédé ainsi que leur utilisation
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus
EP0021337A3 (en) * 1979-06-22 1981-04-22 F. Hoffmann-La Roche & Co. Aktiengesellschaft Preparations for parenteral administration of fat-soluble drugs
EP0036676A1 (en) * 1978-03-24 1981-09-30 The Regents Of The University Of California Method of making uniformly sized liposomes and liposomes so made
EP0043327A1 (fr) * 1980-07-01 1982-01-06 L'oreal Procédé d'obtention de dispersions stables dans une phase aqueuse d'au moins une phase liquide non miscible à l'eau et dispersions correspondantes
EP0065292A3 (en) * 1981-05-15 1983-05-25 Klaus Prof. Dr. Gersonde Process for preparing storage-stable lipid vesicles, application of the process, and lipid vesicles prepared according to the process
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
WO1987005803A1 (en) * 1986-04-01 1987-10-08 Aktiebolaget Draco COMPOSITIONS OF LIPOSOMES AND beta2-RECEPTOR ACTIVE SUBSTANCES
WO1992010166A1 (en) * 1990-12-11 1992-06-25 Sintetica S.A. Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated
EP0191824B1 (en) * 1984-08-08 1993-10-27 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31609E (en) * 1976-10-12 1984-06-19 Lipid Specialties, Inc. Method of preparing a controlled-release pharmaceutical preparation, and resulting composition
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4460577A (en) * 1977-09-30 1984-07-17 Farmitalia Carlo Erba S.P.A. Pharmaceutical compositions consisting or consisting essentially of liposomes, and processes for making same
US4356167A (en) * 1978-01-27 1982-10-26 Sandoz, Inc. Liposome drug delivery systems
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
US4261975A (en) * 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US4341215A (en) * 1980-09-04 1982-07-27 Tampax Incorporated Absorbent device
JPS5782310A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
JPS57109835U (OSRAM) * 1980-12-26 1982-07-07
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4426330A (en) * 1981-07-20 1984-01-17 Lipid Specialties, Inc. Synthetic phospholipid compounds
NL193099C (nl) * 1981-10-30 1998-11-03 Novo Industri As Gestabiliseerde insuline-oplossing.
US4917897A (en) * 1982-01-22 1990-04-17 Fisons Plc Pharmaceutical compositions
DE3365744D1 (en) * 1982-01-22 1986-10-09 Fisons Plc Liposome and sodium cromoglycate compositions, and methods for their preparation
US4452747A (en) * 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
JPS5979137U (ja) * 1982-11-18 1984-05-29 株式会社ソ−ラ− 芳香液容器の蒸散量調節蓋
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
EP0152379A3 (de) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
CH668554A5 (de) * 1984-04-09 1989-01-13 Sandoz Ag Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
US5008050A (en) * 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
CA1264668C (en) * 1984-06-20 1990-01-23 EXTRUSION TECHNIQUES FOR THE PRODUCTION OF LIPOSOMES
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US4897269A (en) * 1984-09-24 1990-01-30 Mezei Associates Limited Administration of drugs with multiphase liposomal delivery system
US4761288A (en) * 1984-09-24 1988-08-02 Mezei Associates Limited Multiphase liposomal drug delivery system
US4737276A (en) * 1984-12-21 1988-04-12 E. I. Du Pont De Nemours And Company Apparatus for manufacturing liposomes
US4622188A (en) * 1984-12-21 1986-11-11 E. I. Du Pont De Nemours And Company Method for manufacturing liposomes
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
US4975282A (en) * 1985-06-26 1990-12-04 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies
DE3689769T2 (de) * 1985-07-05 1994-07-21 Liposome Co Inc Multilamellare liposome mit verbesserter einschliessungswirkung.
AU633563B2 (en) * 1986-02-21 1993-02-04 Bayer Yakuhin, Ltd. Cycloalkanonesulphonamides
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
US5371109A (en) * 1986-07-01 1994-12-06 Drilletten Ab Controlled release composition for a biologically active material dissolved or dispersed in an L2-phase
US5133973A (en) * 1986-08-07 1992-07-28 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Pharmaceutical preparations
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
JPS6355914U (OSRAM) * 1986-09-30 1988-04-14
EP0498471B1 (en) * 1986-12-23 1996-08-14 The Liposome Company, Inc. Liposomes comprising a guanidino aminoglycoside
EP0414663A4 (en) * 1987-04-16 1991-07-17 The Liposome Company, Inc. Liposome continuous size reduction method and apparatus
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
DE3851842T2 (de) * 1987-10-19 1995-03-02 Liposome Co Inc Wässrige bereitung von liposomenzusammensetzungen.
US4981690A (en) * 1987-10-27 1991-01-01 Board Of Regents, The University Of Texas System Liposome-incorporated mepartricin
US4917892A (en) * 1988-06-28 1990-04-17 Temple University Encapsulated topical delivery system
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products
WO1990003795A1 (en) * 1988-10-05 1990-04-19 Vestar, Inc. Method of making liposomes with improved stability during drying
US6132763A (en) * 1988-10-20 2000-10-17 Polymasc Pharmaceuticals Plc Liposomes
US5015483A (en) * 1989-02-09 1991-05-14 Nabisco Brands, Inc. Liposome composition for the stabilization of oxidizable substances
US5139803A (en) * 1989-02-09 1992-08-18 Nabisco, Inc. Method and liposome composition for the stabilization of oxidizable substances
US5221535A (en) * 1989-11-13 1993-06-22 Nova Pharmaceutical Corporation Sustained release formulations of insect repellent
US5227165A (en) * 1989-11-13 1993-07-13 Nova Pharmaceutical Corporation Liposphere delivery systems for local anesthetics
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
IE904098A1 (en) * 1989-11-13 1991-05-22 Nova Pharm Corp Lipospheres for controlled delivery of substances
DK0555229T3 (da) * 1990-07-31 1996-08-19 Liposome Co Inc Akkumulation af aminosyrer og peptider i liposomer
US5990077A (en) 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
US5834428A (en) * 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
ATE386506T1 (de) * 1995-10-17 2008-03-15 Jagotec Ag Verabreichung unlöslicher arzneistoffe
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
US6183774B1 (en) 1996-01-31 2001-02-06 Collaborative Laboratories, Inc. Stabilizing vitamin A derivatives by encapsulation in lipid vesicles formed with alkylammonium fatty acid salts
US5874105A (en) * 1996-01-31 1999-02-23 Collaborative Laboratories, Inc. Lipid vesicles formed with alkylammonium fatty acid salts
EP1231219B1 (en) 1996-04-12 2010-08-25 1149336 Ontario Inc. GLucagon-like peptide-2 analogs
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6037125A (en) * 1996-11-05 2000-03-14 Lexicon Genetics Incorporated Disruption of the mammalian RAD51 protein and disruption of proteins that associate with mammalian RAD51 for hindering cell proliferation and/or viability of proliferating cells
US5968895A (en) 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20070185032A1 (en) * 1996-12-11 2007-08-09 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
CA2236519C (en) 1997-05-02 2011-09-13 1149336 Ontario Inc. Methods of enhancing functioning of the large intestine
DE69908304T2 (de) * 1998-02-11 2004-02-19 Rtp Pharma Corp. Ungesättigte fettsäure und steroide enthaltende kombinationspräparate zur behandlung von entzündungen
US6228840B1 (en) 1998-02-27 2001-05-08 Edward T. Wei Melanocortin receptor antagonists and modulations of melanocortin receptor activity
DE69914742T2 (de) 1998-05-29 2004-11-25 Skyepharma Canada Inc., Verdun Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
ES2211151T3 (es) 1998-08-19 2004-07-01 Skyepharma Canada Inc. Dispersiones acuosas inyectables de propofol.
IL143104A (en) * 1998-11-13 2005-09-25 Optime Therapeutics Inc Method and apparatus for liposome production
US6855296B1 (en) 1998-11-13 2005-02-15 Optime Therapeutics, Inc. Method and apparatus for liposome production
RU2233654C2 (ru) 1998-11-20 2004-08-10 Ртп Фарма Инк. Диспергируемые стабилизированные фосфолипидом микрочастицы
CA2290220C (en) 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
US7132106B2 (en) * 1998-12-22 2006-11-07 Pfizer Inc. Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7618797B2 (en) * 1998-12-22 2009-11-17 Pfizer Inc Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7691389B2 (en) 1998-12-22 2010-04-06 Pfizer Inc Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
EP1035133B1 (en) * 1999-02-17 2005-01-05 Pfizer Products Inc. Fusion proteins comprising carriers that can induce a dual immune response
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
EP1377554A1 (en) 1999-06-16 2004-01-07 University Of Iowa Research Foundation Antagonism of immunostimulatory cpg-oligonucleotides by 4-aminoquinolines and other weak bases
CN1174741C (zh) * 1999-09-21 2004-11-10 Rtp药品公司 生物活性物质的表面改性微粒组合物
US6710038B1 (en) 1999-12-14 2004-03-23 Kibun Food Chemifa Co., Ltd. Emulsification method using propylene glycol hyaluronate
AU5711501A (en) 2000-04-20 2001-11-07 Rtp Pharma Inc Improved water-insoluble drug particle process
ES2325057T3 (es) 2000-08-31 2009-08-25 Jagotec Ag Particulas molturadas.
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
CA2423336C (en) * 2000-09-20 2011-03-08 Rtp Pharma Inc. Stabilised fibrate microparticles
CA2427467C (en) * 2000-11-09 2010-01-12 Neopharm, Inc. Sn-38 lipid complexes and methods of use
ATE357216T1 (de) * 2001-02-22 2007-04-15 Jagotec Ag Fibrat-statin kombinationen mit verminderten von der nahrungsaufnahme abhängigen auswirkungen
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
US6872827B2 (en) * 2002-04-26 2005-03-29 Chembridge Research Laboratories, Inc. Somatostatin analogue compounds
AU2003296897A1 (en) * 2002-08-20 2004-05-04 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
US20040224010A1 (en) * 2002-11-15 2004-11-11 Optime Therapeutics, Inc. Ophthalmic liposome compositions and uses thereof
US20060193825A1 (en) * 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20050112087A1 (en) * 2003-04-29 2005-05-26 Musso Gary F. Pharmaceutical formulations for sustained drug delivery
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
WO2008085794A2 (en) 2007-01-03 2008-07-17 Burnham Institute For Medical Research Methods and compositions related to clot binding compounds
WO2009017863A2 (en) 2007-05-08 2009-02-05 Burnham Institute For Medical Research Tissue non-specific alkaline phosphatase inhibitors and uses thereof for treating vascular calcification
EP2155894A4 (en) 2007-05-09 2010-08-18 Burnham Inst Medical Research HOST PROTEINAS AS A TARGET FOR A THERAPEUTIC STRATEGY AGAINST VIRAL AND BACTERIAL DISEASES
US7960336B2 (en) 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
US8501912B2 (en) * 2007-12-03 2013-08-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Filipil compositions and methods for treating cancer
EP2356132A2 (en) * 2008-10-16 2011-08-17 Pfizer Inc. Torque teno virus (ttv) isolates and compositions
FR2950807B1 (fr) * 2009-10-06 2012-02-03 Lvmh Rech Composition cosmetique contenant des liposomes encapsules dans un compose oxazolidin-2-one
US20110081293A1 (en) 2009-10-07 2011-04-07 Sanford-Burnham Medical Research Institute Methods and compositions related to clot-binding lipid compounds
US8846388B2 (en) 2009-10-16 2014-09-30 Zoetis Llc Infectious clones of torque teno virus
CA2784145A1 (en) 2009-12-18 2011-06-23 Sanford-Burnham Medical Research Institute Methods and compositions related to clot-binding compounds
JP6184101B2 (ja) 2009-12-23 2017-08-23 サンフォード−バーナム メディカル リサーチ インスティテュート アネキシン１結合化合物に関する方法および組成物
RU2462236C2 (ru) * 2010-03-22 2012-09-27 Государственное Образовательное Учреждение Высшего Профессионального Образования "Омский Государственный Технический Университет" Липосомальная нанокапсула
RU2446789C2 (ru) * 2010-03-22 2012-04-10 Государственное Образовательное Учреждение Высшего Профессионального Образования "Омский Государственный Технический Университет" Липосомальная нанокапсула
JP2013525285A (ja) 2010-04-08 2013-06-20 サンフォード−バーナム メディカル リサーチ インスティテュート 化合物の送達を増強するための方法および組成物
EP2555791B1 (en) 2010-04-09 2017-11-01 Sinai Health System Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
UA108902C2 (uk) 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
WO2012118778A1 (en) 2011-02-28 2012-09-07 Sanford-Burnham Medical Research Institute Truncated car peptides and methods and compositions using truncated car peptides
US20140286980A1 (en) 2011-06-08 2014-09-25 Zoetis Llc Infectious clones of torque teno virus
US10179801B2 (en) 2011-08-26 2019-01-15 Sanford-Burnham Medical Research Institute Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides
US8877161B2 (en) 2011-10-19 2014-11-04 Georgia Regents Research Institute, Inc. GM1-like peptides and uses thereof
CA2872789C (en) 2012-05-17 2019-09-03 Zoetis Llc Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning
EP3019188B1 (en) 2013-07-08 2022-03-09 The University of Utah Research Foundation A peptide and the use thereof in the treatment of inflammatory disorders
US10500246B2 (en) 2015-06-25 2019-12-10 Sanford Burnham Prebys Medical Discovery Institute Compositions for delivery to and treatment of atherosclerotic plaques
US11013798B2 (en) 2016-03-21 2021-05-25 South Dakota Board Of Regents Orf virus-based platform for vaccine delivery
CN110072547B (zh) 2016-12-14 2024-04-30 硕腾服务有限责任公司 断奶前对抗欧洲猪繁殖与呼吸综合征(prrs)病毒株的有效疫苗接种
EP3628047A1 (en) 2017-05-02 2020-04-01 Sanford Burnham Prebys Medical Discovery Institute Tumor associated monocyte/macrophage binding peptide and methods of use thereof
WO2018204918A1 (en) 2017-05-05 2018-11-08 Ardelyx, Inc. Treatment of hepatic disorders
US10953085B2 (en) 2017-05-09 2021-03-23 Lawrence Livermore National Security, Llc Genetically engineered Foot and Mouth Disease Virus and related proteins, polynucleotides, compositions, methods and systems
CA3120179A1 (en) * 2018-12-21 2020-06-25 Bracco Suisse Sa Gas-filled microvesicles with ligand
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3056728A (en) * 1958-10-14 1962-10-02 Ohtaki Shinshiro Process for manufacturing powdered preparations containing fat-soluble vitamins, essential oils, and mixtures thereof
US3780195A (en) * 1969-10-22 1973-12-18 Balchem Corp Encapsulation process

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399241A1 (fr) * 1977-08-05 1979-03-02 Battelle Memorial Institute Procede de deshydratation d'une dispersion colloidale de liposomes
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4247411A (en) * 1978-02-02 1981-01-27 L'oreal Storage stability of aqueous dispersions of spherules
EP0004223A1 (fr) * 1978-02-24 1979-09-19 PAPAHADJOPOULOS, Demetrios P. Procédé de fabrication de capsules lipidiques renfermant un matériau biologiquement actif, produits obtenus par ce procédé ainsi que leur utilisation
FR2418023A1 (fr) * 1978-02-24 1979-09-21 Papahadjopoulos Demetrios Procede de fabrication de capsules lipidiques renfermant un materiau biologiquement actif et capsules ainsi obtenues
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
EP0036676A1 (en) * 1978-03-24 1981-09-30 The Regents Of The University Of California Method of making uniformly sized liposomes and liposomes so made
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus
EP0021337A3 (en) * 1979-06-22 1981-04-22 F. Hoffmann-La Roche & Co. Aktiengesellschaft Preparations for parenteral administration of fat-soluble drugs
EP0043327A1 (fr) * 1980-07-01 1982-01-06 L'oreal Procédé d'obtention de dispersions stables dans une phase aqueuse d'au moins une phase liquide non miscible à l'eau et dispersions correspondantes
US5055228A (en) * 1980-07-01 1991-10-08 L'oreal Process for the preparation of stable dispersions of at least one water-immiscible liquid phase in an aqueous phase
US5154854A (en) * 1980-07-01 1992-10-13 L'oreal Process for the preparation of stable dispersions of at least one water-immiscible liquid phase in an aqueous phase
EP0065292A3 (en) * 1981-05-15 1983-05-25 Klaus Prof. Dr. Gersonde Process for preparing storage-stable lipid vesicles, application of the process, and lipid vesicles prepared according to the process
EP0191824B1 (en) * 1984-08-08 1993-10-27 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
WO1987005803A1 (en) * 1986-04-01 1987-10-08 Aktiebolaget Draco COMPOSITIONS OF LIPOSOMES AND beta2-RECEPTOR ACTIVE SUBSTANCES
WO1992010166A1 (en) * 1990-12-11 1992-06-25 Sintetica S.A. Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated

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GB1487989A (en) 1977-10-05
FR2298318B1 (OSRAM) 1978-12-08
DE2601207A1 (de) 1976-07-29
JPS5186117A (en) 1976-07-28
US4016100A (en) 1977-04-05
DE2601207C3 (de) 1980-07-10
DE2601207B2 (de) 1979-10-25
JPS558488B2 (OSRAM) 1980-03-04

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