FR2298318A1 - Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti - Google Patents

Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti

Info

Publication number
FR2298318A1
FR2298318A1 FR7602016A FR7602016A FR2298318A1 FR 2298318 A1 FR2298318 A1 FR 2298318A1 FR 7602016 A FR7602016 A FR 7602016A FR 7602016 A FR7602016 A FR 7602016A FR 2298318 A1 FR2298318 A1 FR 2298318A1
Authority
FR
France
Prior art keywords
acti
preparing
principle
pharmaceutical composition
liquid pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7602016A
Other languages
English (en)
Other versions
FR2298318B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2298318A1 publication Critical patent/FR2298318A1/fr
Application granted granted Critical
Publication of FR2298318B1 publication Critical patent/FR2298318B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7602016A 1975-01-27 1976-01-26 Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti Granted FR2298318A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50011751A JPS5186117A (en) 1975-01-27 1975-01-27 Johoseibiryushiseizainoseiho

Publications (2)

Publication Number Publication Date
FR2298318A1 true FR2298318A1 (fr) 1976-08-20
FR2298318B1 FR2298318B1 (fr) 1978-12-08

Family

ID=11786697

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7602016A Granted FR2298318A1 (fr) 1975-01-27 1976-01-26 Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti

Country Status (5)

Country Link
US (1) US4016100A (fr)
JP (1) JPS5186117A (fr)
DE (1) DE2601207C3 (fr)
FR (1) FR2298318A1 (fr)
GB (1) GB1487989A (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399241A1 (fr) * 1977-08-05 1979-03-02 Battelle Memorial Institute Procede de deshydratation d'une dispersion colloidale de liposomes
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
EP0004223A1 (fr) * 1978-02-24 1979-09-19 PAPAHADJOPOULOS, Demetrios P. Procédé de fabrication de capsules lipidiques renfermant un matériau biologiquement actif, produits obtenus par ce procédé ainsi que leur utilisation
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus
EP0021337A2 (fr) * 1979-06-22 1981-01-07 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Préparations pour l'administration parentérale de médicaments liposolubles
EP0036676A1 (fr) * 1978-03-24 1981-09-30 The Regents Of The University Of California Procédé de préparation de liposomes de taille identique et les liposomes ainsi obtenus
EP0043327A1 (fr) * 1980-07-01 1982-01-06 L'oreal Procédé d'obtention de dispersions stables dans une phase aqueuse d'au moins une phase liquide non miscible à l'eau et dispersions correspondantes
EP0065292A2 (fr) * 1981-05-15 1982-11-24 Klaus Prof. Dr. Gersonde Procédé de stockage de vésicules phospholipidiques unilamellaires
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
EP0191824A1 (fr) * 1984-08-08 1986-08-27 Liposome Co Inc Encapsulement d'agents antineoplastiques dans des liposomes.
WO1987005803A1 (fr) * 1986-04-01 1987-10-08 Aktiebolaget Draco COMPOSITIONS DE LIPOSOMES ET SUBSTANCES ACTIVES beta2-RECEPTRICES
WO1992010166A1 (fr) * 1990-12-11 1992-06-25 Sintetica S.A. Procede de production de liposomes a capacite accrue de piegeage des substances etrangeres a encapsuler
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
USRE31609E (en) * 1976-10-12 1984-06-19 Lipid Specialties, Inc. Method of preparing a controlled-release pharmaceutical preparation, and resulting composition
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4460577A (en) * 1977-09-30 1984-07-17 Farmitalia Carlo Erba S.P.A. Pharmaceutical compositions consisting or consisting essentially of liposomes, and processes for making same
US4356167A (en) * 1978-01-27 1982-10-26 Sandoz, Inc. Liposome drug delivery systems
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
US4261975A (en) * 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US4341215A (en) * 1980-09-04 1982-07-27 Tampax Incorporated Absorbent device
JPS62682Y2 (fr) * 1980-11-05 1987-01-09
JPS5782310A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
JPS57109835U (fr) * 1980-12-26 1982-07-07
JPS62684Y2 (fr) * 1980-12-30 1987-01-09
JPS5850917Y2 (ja) * 1981-04-24 1983-11-19 大正製薬株式会社 揮発性液剤分与器
US4426330A (en) * 1981-07-20 1984-01-17 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
NL193099C (nl) * 1981-10-30 1998-11-03 Novo Industri As Gestabiliseerde insuline-oplossing.
EP0084898B1 (fr) * 1982-01-22 1986-09-03 FISONS plc Compostions contenant de liposomes et cromoglycate disodique et méthodes de leur préparation
US4917897A (en) * 1982-01-22 1990-04-17 Fisons Plc Pharmaceutical compositions
US4452747A (en) * 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
JPS5979137U (ja) * 1982-11-18 1984-05-29 株式会社ソ−ラ− 芳香液容器の蒸散量調節蓋
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
EP0152379A3 (fr) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Procédé pour la préparation de compositions pharmaceutiques contenant des liposomes unilamellaires
CH668554A5 (de) * 1984-04-09 1989-01-13 Sandoz Ag Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
US5008050A (en) * 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
CA1264668A (fr) * 1984-06-20 1990-01-23 Pieter R. Cullis Techniques d'extrusion pour la production de liposomes
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US4897269A (en) * 1984-09-24 1990-01-30 Mezei Associates Limited Administration of drugs with multiphase liposomal delivery system
US4761288A (en) * 1984-09-24 1988-08-02 Mezei Associates Limited Multiphase liposomal drug delivery system
US4622188A (en) * 1984-12-21 1986-11-11 E. I. Du Pont De Nemours And Company Method for manufacturing liposomes
US4737276A (en) * 1984-12-21 1988-04-12 E. I. Du Pont De Nemours And Company Apparatus for manufacturing liposomes
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
US4975282A (en) * 1985-06-26 1990-12-04 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies
WO1987000043A1 (fr) * 1985-07-05 1987-01-15 The Liposome Company, Inc. Liposomes multilamellaires presentant une efficacite de capture amelioree
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
AU633563B2 (en) * 1986-02-21 1993-02-04 Bayer Yakuhin, Ltd. Cycloalkanonesulphonamides
US5371109A (en) * 1986-07-01 1994-12-06 Drilletten Ab Controlled release composition for a biologically active material dissolved or dispersed in an L2-phase
US5133973A (en) * 1986-08-07 1992-07-28 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Pharmaceutical preparations
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
JPS6355914U (fr) * 1986-09-30 1988-04-14
ATE141166T1 (de) * 1986-12-23 1996-08-15 Liposome Co Inc Guanidinaminoglycosid enthaltende liposome
EP0414663A4 (en) * 1987-04-16 1991-07-17 The Liposome Company, Inc. Liposome continuous size reduction method and apparatus
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
EP0382777B1 (fr) * 1987-10-19 1994-10-12 The Liposome Company, Inc. Preparation aqueuse de composition de liposomes
US4981690A (en) * 1987-10-27 1991-01-01 Board Of Regents, The University Of Texas System Liposome-incorporated mepartricin
US4917892A (en) * 1988-06-28 1990-04-17 Temple University Encapsulated topical delivery system
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products
DE68916439T2 (de) * 1988-10-05 1994-10-20 Vestar Inc Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
US6132763A (en) * 1988-10-20 2000-10-17 Polymasc Pharmaceuticals Plc Liposomes
US5015483A (en) * 1989-02-09 1991-05-14 Nabisco Brands, Inc. Liposome composition for the stabilization of oxidizable substances
US5139803A (en) * 1989-02-09 1992-08-18 Nabisco, Inc. Method and liposome composition for the stabilization of oxidizable substances
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
US5227165A (en) * 1989-11-13 1993-07-13 Nova Pharmaceutical Corporation Liposphere delivery systems for local anesthetics
US5221535A (en) * 1989-11-13 1993-06-22 Nova Pharmaceutical Corporation Sustained release formulations of insect repellent
IE904098A1 (en) * 1989-11-13 1991-05-22 Nova Pharm Corp Lipospheres for controlled delivery of substances
WO1992002244A1 (fr) * 1990-07-31 1992-02-20 The Liposome Company, Inc. Accumulation d'acides amines et de peptides dans des liposomes
US5834428A (en) * 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US5990077A (en) 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
DE69637441T2 (de) * 1995-10-17 2009-03-05 Jagotec Ag Verabreichung unlöslicher arzneistoffe
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
US6183774B1 (en) 1996-01-31 2001-02-06 Collaborative Laboratories, Inc. Stabilizing vitamin A derivatives by encapsulation in lipid vesicles formed with alkylammonium fatty acid salts
US5874105A (en) * 1996-01-31 1999-02-23 Collaborative Laboratories, Inc. Lipid vesicles formed with alkylammonium fatty acid salts
AU733857B2 (en) 1996-04-12 2001-05-31 1149336 Ontario Inc. Glucagon-like peptide-2 analogs
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6037125A (en) * 1996-11-05 2000-03-14 Lexicon Genetics Incorporated Disruption of the mammalian RAD51 protein and disruption of proteins that associate with mammalian RAD51 for hindering cell proliferation and/or viability of proliferating cells
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20070185032A1 (en) * 1996-12-11 2007-08-09 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
CA2236519C (fr) 1997-05-02 2011-09-13 1149336 Ontario Inc. Methodes pour ameliorer le fonctionnement du gros intestin
IL137734A0 (en) * 1998-02-11 2001-10-31 Res Triangle Pharm Ltd Method and composition for treatment of inflammatory conditions
US6228840B1 (en) 1998-02-27 2001-05-08 Edward T. Wei Melanocortin receptor antagonists and modulations of melanocortin receptor activity
JP2002516267A (ja) 1998-05-29 2002-06-04 アールティーピー・ファーマ・インコーポレーテッド 熱的に保護された微粒子組成物及びその最終蒸気滅菌
DK1105096T3 (da) 1998-08-19 2004-03-08 Skyepharma Canada Inc Injicerbare vandige propofoldispersioner
US6855296B1 (en) 1998-11-13 2005-02-15 Optime Therapeutics, Inc. Method and apparatus for liposome production
IL143104A (en) 1998-11-13 2005-09-25 Optime Therapeutics Inc Method and apparatus for liposome production
KR20010073232A (ko) * 1998-11-20 2001-07-31 추후제출 분산성 인지질로 안정화된 마이크로입자
NZ501264A (en) 1998-12-22 2001-09-28 Pfizer Prod Inc Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS
US7691389B2 (en) 1998-12-22 2010-04-06 Pfizer Inc Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7618797B2 (en) * 1998-12-22 2009-11-17 Pfizer Inc Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7132106B2 (en) * 1998-12-22 2006-11-07 Pfizer Inc. Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
ES2233284T3 (es) * 1999-02-17 2005-06-16 Pfizer Products Inc. Proteinas de fusion que comprenden portadores que pueden inducir una bdoble respuesta inmune.
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
WO2000076982A1 (fr) 1999-06-16 2000-12-21 University Of Iowa Research Foundation Antagonisme des oligonucleotides cpg immunostimulateurs par des 4-aminoquinolines et autres bases faibles
IL148685A0 (en) * 1999-09-21 2002-09-12 Rtp Pharma Inc Surface modified particulate compositions of biologically active substances
US6710038B1 (en) 1999-12-14 2004-03-23 Kibun Food Chemifa Co., Ltd. Emulsification method using propylene glycol hyaluronate
EP1276465B1 (fr) 2000-04-20 2014-03-12 Jagotec AG Procede ameliore destine aux particules de medicament insolubles dans l'eau
JP4969761B2 (ja) 2000-08-31 2012-07-04 オバン・エナジー・リミテッド 所望粒度を持つ固体基材の小粒子および第一材料の小粒状物を含む相乗作用性混合物を製造する方法
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
WO2002024193A1 (fr) * 2000-09-20 2002-03-28 Skyepharma Canada Inc. Microparticules de fibrate stabilisees
SK7092003A3 (en) * 2000-11-09 2004-06-08 Neopharm Inc SN-38 lipid complexes and methods of use
US6534088B2 (en) * 2001-02-22 2003-03-18 Skyepharma Canada Inc. Fibrate-statin combinations with reduced fed-fasted effects
WO2003030864A1 (fr) * 2001-05-29 2003-04-17 Neopharm, Inc. Formulation liposomale d'irinotecan
US6872827B2 (en) * 2002-04-26 2005-03-29 Chembridge Research Laboratories, Inc. Somatostatin analogue compounds
WO2004035032A2 (fr) * 2002-08-20 2004-04-29 Neopharm, Inc. Formulation de sn-38 a base de lipides pharmaceutiquement actifs
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
US20040224010A1 (en) * 2002-11-15 2004-11-11 Optime Therapeutics, Inc. Ophthalmic liposome compositions and uses thereof
US20060193825A1 (en) * 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20050112087A1 (en) * 2003-04-29 2005-05-26 Musso Gary F. Pharmaceutical formulations for sustained drug delivery
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
EP2117575A4 (fr) 2007-01-03 2013-06-05 Burnham Inst Medical Research Méthodes et compositions associées à des composés adhérant aux caillots
JP5671336B2 (ja) 2007-05-08 2015-02-18 バーナム インスティテュート フォー メディカル リサーチ 組織非特異的アルカリホスファターゼ阻害因子および血管石灰化を処置するためのそれらの使用
US8053553B2 (en) 2007-05-09 2011-11-08 Socpra Sciences Sante Et Humaines Targeting host proteinases as a therapeutic strategy against viral and bacterial pathogens
US7960336B2 (en) 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
WO2010070380A2 (fr) * 2007-12-03 2010-06-24 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health Of Human Services, National Institutes Of Health Compositions doc1 et méthodes de traitement du cancer
KR20130054466A (ko) * 2008-10-16 2013-05-24 화이자 인코포레이티드 토크 테노 바이러스(ｔｔｖ) 분리물 및 조성물
FR2950807B1 (fr) * 2009-10-06 2012-02-03 Lvmh Rech Composition cosmetique contenant des liposomes encapsules dans un compose oxazolidin-2-one
US20110081293A1 (en) 2009-10-07 2011-04-07 Sanford-Burnham Medical Research Institute Methods and compositions related to clot-binding lipid compounds
US8846388B2 (en) 2009-10-16 2014-09-30 Zoetis Llc Infectious clones of torque teno virus
JP2013515008A (ja) 2009-12-18 2013-05-02 サンフォード−バーナム メディカル リサーチ インスティテュート 凝血塊結合化合物に関連する方法および組成物
WO2011079304A1 (fr) 2009-12-23 2011-06-30 Sanford-Burnham Medical Research Institute Méthodes et compositions se rapportant à des composés se liant à l'annexine 1
CA2795289A1 (fr) 2010-04-08 2011-10-13 Sanford-Burnham Medical Research Institute Methodes et compositions pour une administration amelioree de composes
WO2011123943A1 (fr) 2010-04-09 2011-10-13 Mount Sinai Hospital Méthodes de traitement de troubles du tractus gastro-intestinal au moyen d'un agoniste glp-1
UA108902C2 (uk) 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
WO2012118778A1 (fr) 2011-02-28 2012-09-07 Sanford-Burnham Medical Research Institute Peptides car tronqués, procédés et compositions les utilisant
EP2718429A1 (fr) 2011-06-08 2014-04-16 Zoetis LLC Clones infectieux du virus torque teno
US10179801B2 (en) 2011-08-26 2019-01-15 Sanford-Burnham Medical Research Institute Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides
US8877161B2 (en) 2011-10-19 2014-11-04 Georgia Regents Research Institute, Inc. GM1-like peptides and uses thereof
WO2013173443A1 (fr) 2012-05-17 2013-11-21 Zoetis Llc Vaccination efficace contre le virus du syndrome reproducteur et respiratoire porcin (srrp) avant le sevrage
EP4219534A3 (fr) 2013-07-08 2023-09-27 The University of Utah Research Foundation Procédés de traitement et de prophylatise contre les troubles inflammatoires
EP3313447A2 (fr) 2015-06-25 2018-05-02 Sanford Burnham Prebys Medical Discovery Institute Compositions à administrer dans des plaques athéroscléreuses, pour le traitement de ces plaques
BR112018069371A2 (pt) 2016-03-21 2019-01-22 South Dakota Board Of Regents construção de ácido nucleico, vetor, vacina ou composição imunogênica, método de entrega de uma vacina, método de produção de uma construção de ácido nucleico e método para conferir imunidade contra um antígeno
BR112019012158A2 (pt) 2016-12-14 2019-11-12 Zoetis Services Llc vacinação eficaz contra cepas europeias de vírus da síndrome reprodutiva e respiratória suína (prrs) antes do desmame
EP3628047A1 (fr) 2017-05-02 2020-04-01 Sanford Burnham Prebys Medical Discovery Institute Peptide liant des monocytes/macrophages associés à une tumeur et procédés d'utilisation associés
WO2018204918A1 (fr) 2017-05-05 2018-11-08 Ardelyx, Inc. Traitement de troubles hépatiques
US10953085B2 (en) 2017-05-09 2021-03-23 Lawrence Livermore National Security, Llc Genetically engineered Foot and Mouth Disease Virus and related proteins, polynucleotides, compositions, methods and systems
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US20220119450A1 (en) 2019-02-04 2022-04-21 University Of Tartu Bi-specific extracellular matrix binding peptides and methods of use thereof
CN111084387A (zh) * 2019-12-24 2020-05-01 李晨悦 多功能营养组合物及其制备方法和保健食品
CN114315985A (zh) 2020-09-29 2022-04-12 硕腾服务有限责任公司 减毒猪流行性腹泻病毒
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3056728A (en) * 1958-10-14 1962-10-02 Ohtaki Shinshiro Process for manufacturing powdered preparations containing fat-soluble vitamins, essential oils, and mixtures thereof
US3780195A (en) * 1969-10-22 1973-12-18 Balchem Corp Encapsulation process

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399241A1 (fr) * 1977-08-05 1979-03-02 Battelle Memorial Institute Procede de deshydratation d'une dispersion colloidale de liposomes
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4247411A (en) * 1978-02-02 1981-01-27 L'oreal Storage stability of aqueous dispersions of spherules
EP0004223A1 (fr) * 1978-02-24 1979-09-19 PAPAHADJOPOULOS, Demetrios P. Procédé de fabrication de capsules lipidiques renfermant un matériau biologiquement actif, produits obtenus par ce procédé ainsi que leur utilisation
FR2418023A1 (fr) * 1978-02-24 1979-09-21 Papahadjopoulos Demetrios Procede de fabrication de capsules lipidiques renfermant un materiau biologiquement actif et capsules ainsi obtenues
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
EP0036676A1 (fr) * 1978-03-24 1981-09-30 The Regents Of The University Of California Procédé de préparation de liposomes de taille identique et les liposomes ainsi obtenus
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus
EP0021337A2 (fr) * 1979-06-22 1981-01-07 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Préparations pour l'administration parentérale de médicaments liposolubles
EP0021337A3 (en) * 1979-06-22 1981-04-22 F. Hoffmann-La Roche & Co. Aktiengesellschaft Preparations for parenteral administration of fat-soluble drugs
US5055228A (en) * 1980-07-01 1991-10-08 L'oreal Process for the preparation of stable dispersions of at least one water-immiscible liquid phase in an aqueous phase
EP0043327A1 (fr) * 1980-07-01 1982-01-06 L'oreal Procédé d'obtention de dispersions stables dans une phase aqueuse d'au moins une phase liquide non miscible à l'eau et dispersions correspondantes
US5154854A (en) * 1980-07-01 1992-10-13 L'oreal Process for the preparation of stable dispersions of at least one water-immiscible liquid phase in an aqueous phase
EP0065292A3 (en) * 1981-05-15 1983-05-25 Klaus Prof. Dr. Gersonde Process for preparing storage-stable lipid vesicles, application of the process, and lipid vesicles prepared according to the process
EP0065292A2 (fr) * 1981-05-15 1982-11-24 Klaus Prof. Dr. Gersonde Procédé de stockage de vésicules phospholipidiques unilamellaires
EP0191824A1 (fr) * 1984-08-08 1986-08-27 Liposome Co Inc Encapsulement d'agents antineoplastiques dans des liposomes.
EP0191824B1 (fr) * 1984-08-08 1993-10-27 The Liposome Company, Inc. Encapsulement d'agents antineoplastiques dans des liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
WO1987005803A1 (fr) * 1986-04-01 1987-10-08 Aktiebolaget Draco COMPOSITIONS DE LIPOSOMES ET SUBSTANCES ACTIVES beta2-RECEPTRICES
WO1992010166A1 (fr) * 1990-12-11 1992-06-25 Sintetica S.A. Procede de production de liposomes a capacite accrue de piegeage des substances etrangeres a encapsuler

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US4016100A (en) 1977-04-05
DE2601207B2 (de) 1979-10-25
DE2601207C3 (de) 1980-07-10
JPS5186117A (en) 1976-07-28
FR2298318B1 (fr) 1978-12-08
JPS558488B2 (fr) 1980-03-04
GB1487989A (en) 1977-10-05
DE2601207A1 (de) 1976-07-29

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