FR2562421B1 - Perfectionnements a la therapie par l'interleukine - Google Patents

Perfectionnements a la therapie par l'interleukine

Info

Publication number
FR2562421B1
FR2562421B1 FR858505117A FR8505117A FR2562421B1 FR 2562421 B1 FR2562421 B1 FR 2562421B1 FR 858505117 A FR858505117 A FR 858505117A FR 8505117 A FR8505117 A FR 8505117A FR 2562421 B1 FR2562421 B1 FR 2562421B1
Authority
FR
France
Prior art keywords
interleukin therapy
interleukin
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR858505117A
Other languages
English (en)
Other versions
FR2562421A1 (fr
Inventor
Thomas Kissel
Jurg Reinhardt
Henriette Schrank
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848409126A external-priority patent/GB8409126D0/en
Priority claimed from GB848409128A external-priority patent/GB8409128D0/en
Priority claimed from GB848409127A external-priority patent/GB8409127D0/en
Priority claimed from GB848409125A external-priority patent/GB8409125D0/en
Priority claimed from GB848420381A external-priority patent/GB8420381D0/en
Priority claimed from GB848423701A external-priority patent/GB8423701D0/en
Priority claimed from GB848423700A external-priority patent/GB8423700D0/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2562421A1 publication Critical patent/FR2562421A1/fr
Application granted granted Critical
Publication of FR2562421B1 publication Critical patent/FR2562421B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR858505117A 1984-04-09 1985-04-02 Perfectionnements a la therapie par l'interleukine Expired FR2562421B1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB848409126A GB8409126D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848409128A GB8409128D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848409127A GB8409127D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848409125A GB8409125D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848420381A GB8420381D0 (en) 1984-08-10 1984-08-10 Interleukin therapy
GB848423701A GB8423701D0 (en) 1984-09-19 1984-09-19 Interleukin therapy
GB848423700A GB8423700D0 (en) 1984-09-19 1984-09-19 Interleukin therapy

Publications (2)

Publication Number Publication Date
FR2562421A1 FR2562421A1 (fr) 1985-10-11
FR2562421B1 true FR2562421B1 (fr) 1989-02-17

Family

ID=27562708

Family Applications (1)

Application Number Title Priority Date Filing Date
FR858505117A Expired FR2562421B1 (fr) 1984-04-09 1985-04-02 Perfectionnements a la therapie par l'interleukine

Country Status (13)

Country Link
US (1) US4863740A (fr)
JP (1) JPH0665650B2 (fr)
AU (1) AU4094685A (fr)
CH (1) CH668554A5 (fr)
DE (1) DE3512926A1 (fr)
DK (1) DK155085A (fr)
FR (1) FR2562421B1 (fr)
GB (1) GB2157172B (fr)
IL (1) IL74835A0 (fr)
IT (1) IT1199967B (fr)
LU (1) LU85839A1 (fr)
NL (1) NL8501010A (fr)
SE (1) SE8501709L (fr)

Families Citing this family (46)

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ES2039203T3 (es) * 1985-11-22 1993-09-16 Takeda Chemical Industries, Ltd. Composicion de liposomas.
EP0274219A3 (fr) * 1986-12-04 1988-08-03 Takeda Chemical Industries, Ltd. Composition de liposome contenant de l'interleukine-2 et méthode de sa fabrication
FR2624741B1 (fr) * 1987-12-21 1991-06-28 Pasteur Institut Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire
DE68913003T2 (de) * 1988-05-16 1994-06-09 Vestar Inc An hormone gekoppelte liposome.
EP0577146A3 (fr) * 1988-05-16 1994-02-02 NeXstar Pharmaceuticals, Inc. Liposomes couplés sur des hormones
US5258499A (en) * 1988-05-16 1993-11-02 Vestar, Inc. Liposome targeting using receptor specific ligands
AU4525589A (en) * 1988-10-27 1990-05-14 Regents Of The University Of Minnesota Liposome immunoadjuvants containing il-2
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
ATE136211T1 (de) * 1989-06-23 1996-04-15 Liposome Co Inc Zielliposomen und verfahren zur kupplung von liposomen-proteinen
JPH0363298A (ja) * 1989-07-31 1991-03-19 Green Cross Corp:The コロニー形成刺激因子・脂質複合体
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5268454A (en) * 1991-02-08 1993-12-07 La Jolla Pharmaceutical Company Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5817333A (en) * 1991-10-31 1998-10-06 Fujisawa Pharmaceutical Co., Ltd. Liposome preparation containing a tricyclic compound
EP0624095B2 (fr) * 1991-12-31 2005-07-20 Zymogenetics, Inc. Procedes et compositions pour reduire la perte de sang
US5229109A (en) * 1992-04-14 1993-07-20 Board Of Regents, The University Of Texas System Low toxicity interleukin-2 analogues for use in immunotherapy
SI9300468A (en) * 1992-10-14 1994-06-30 Hoffmann La Roche Injectable composition for the sustained release of biologically active compounds
US5449663A (en) * 1993-06-11 1995-09-12 Bicher; Haim I. Antineoplastic compositions
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6033645A (en) * 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
US6406689B1 (en) 1995-10-03 2002-06-18 Frank W. Falkenberg Compositions and methods for treatment of tumors and metastatic diseases
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US6416740B1 (en) * 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
WO1998052581A1 (fr) 1997-05-20 1998-11-26 Ottawa Civic Hospital Loeb Research Institute Vecteurs et procedes destines a l'immunisation et a des protocoles therapeutiques
ES2245052T3 (es) * 1997-12-01 2005-12-16 Fang Fang Anticuerpos de recombinacion multivalentes destinados para el tratamiento de infecciones debidas al rinovirus humano (hrv).
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
WO1999036056A1 (fr) * 1998-01-16 1999-07-22 Biomira Usa Inc. Preparation de lipomatrice
ATE252889T1 (de) 1998-08-19 2003-11-15 Skyepharma Canada Inc Injizierbare wässerige propofoldispersionen
US20030035798A1 (en) * 2000-08-16 2003-02-20 Fang Fang Humanized antibodies
WO2001068828A2 (fr) 2000-03-13 2001-09-20 Engene, Inc. Compositions et methodes destinees a l'expression regulee d'une proteine dans l'intestin
AU2001249389A1 (en) * 2000-03-22 2001-10-03 The Children's Hospital Of Philadelphia Modified blood clotting factors and methods of use
JP2005522192A (ja) 2001-07-19 2005-07-28 パーラン セラピューティクス， インコーポレイテッド マルチマータンパク質およびマルチマータンパク質を作製および使用する方法
US20030044354A1 (en) * 2001-08-16 2003-03-06 Carpenter Alan P. Gas microsphere liposome composites for ultrasound imaging and ultrasound stimulated drug release
TWI461436B (zh) 2005-11-25 2014-11-21 Kyowa Hakko Kirin Co Ltd 人類ｃｄ１３４（ｏｘ４０）之人類單株抗體及其製造及使用方法
EP1795540A1 (fr) 2005-11-30 2007-06-13 Imaxio Complexes multiples d'antigènes et d'un adjuvant
EP2015785A4 (fr) * 2006-04-24 2009-07-15 Shantha West Inc Antigène agrm2
ES2476798T3 (es) 2006-11-27 2014-07-15 Patrys Limited Nueva diana de p�ptido glucosilado en células neopl�sicas
WO2010117057A1 (fr) 2009-04-10 2010-10-14 協和発酵キリン株式会社 Procédé pour le traitement d'une tumeur sanguine utilisant un anticorps anti-tim-3
PL2426148T3 (pl) 2009-04-27 2016-01-29 Kyowa Hakko Kirin Co Ltd Przeciwciało anty-IL-3RA do stosowania w leczeniu nowotworu krwi
US9556272B2 (en) 2009-11-11 2017-01-31 The Trustees Of The University Of Pennsylvania Anti-TEM1 antibodies and uses thereof
US9783610B2 (en) 2012-04-27 2017-10-10 The Trustees Of The University Of Pennsylvania Anti-tumor endothelial marker-1 (TEM1) antibody variants and uses thereof
JP2016514091A (ja) 2013-02-08 2016-05-19 ミスフォールディング ダイアグノスティクス， インコーポレイテッド トランスサイレチン抗体およびその使用
WO2014210142A1 (fr) 2013-06-25 2014-12-31 Temple University-Of The Commonwealth System Of Higher Education Cellules souches dérivées d'os cortical

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
GB1578776A (en) * 1976-06-10 1980-11-12 Univ Illinois Hemoglobin liposome and method of making the same
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4377567A (en) * 1978-10-02 1983-03-22 The Procter & Gamble Company Lipid membrane drug delivery
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
JPS56127308A (en) * 1980-03-11 1981-10-06 Green Cross Corp:The Blood-coagulation factor 8 pharmaceutical
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
JPH0751511B2 (ja) * 1982-03-15 1995-06-05 味の素株式会社 インターロイキン２を含有してなる癌治療剤
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
AU564876B2 (en) * 1982-03-29 1987-08-27 Liposome Company, Inc., The Stable plurilamellar vesicles
EP0109861A3 (fr) * 1982-11-23 1986-05-14 Bio-Response Inc. Procédé pour isoler des cellules
WO1985000606A1 (fr) * 1983-07-19 1985-02-14 Takeda Chemical Industries, Ltd. Il-2 humaine et son procede de preparation
US4464461A (en) * 1983-07-22 1984-08-07 Eastman Kodak Company Development of light-sensitive quinone diazide compositions
US4764359A (en) * 1984-05-25 1988-08-16 Lemelson Jerome H Drug compositions and their use in treating human or other mammalian patients
CA1260393A (fr) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes de lipides synthetiques

Also Published As

Publication number Publication date
US4863740A (en) 1989-09-05
IT8547939A1 (it) 1986-10-09
NL8501010A (nl) 1985-11-01
DK155085A (da) 1985-10-10
FR2562421A1 (fr) 1985-10-11
LU85839A1 (fr) 1985-12-16
IT8547939A0 (it) 1985-04-09
AU4094685A (en) 1985-10-17
IT1199967B (it) 1989-01-05
JPS60243022A (ja) 1985-12-03
JPH0665650B2 (ja) 1994-08-24
GB2157172B (en) 1988-12-29
IL74835A0 (en) 1985-07-31
DE3512926A1 (de) 1985-10-24
GB2157172A (en) 1985-10-23
SE8501709L (sv) 1985-10-10
CH668554A5 (de) 1989-01-13
DK155085D0 (da) 1985-04-03
SE8501709D0 (sv) 1985-04-04
GB8508809D0 (en) 1985-05-09

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse