IT1199967B - Liposomi contenenti interleucina,metodo per la loro preparazione e loro uso terapeutico nelle affezioni tumorali - Google Patents

Liposomi contenenti interleucina,metodo per la loro preparazione e loro uso terapeutico nelle affezioni tumorali

Info

Publication number
IT1199967B
IT1199967B IT47939/85A IT4793985A IT1199967B IT 1199967 B IT1199967 B IT 1199967B IT 47939/85 A IT47939/85 A IT 47939/85A IT 4793985 A IT4793985 A IT 4793985A IT 1199967 B IT1199967 B IT 1199967B
Authority
IT
Italy
Prior art keywords
interleucin
affections
cancer
preparation
therapeutic use
Prior art date
Application number
IT47939/85A
Other languages
English (en)
Other versions
IT8547939A1 (it
IT8547939A0 (it
Inventor
Thomas Kissel
Reinhard Jurg
Henriette Schrank
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848409125A external-priority patent/GB8409125D0/en
Priority claimed from GB848409126A external-priority patent/GB8409126D0/en
Priority claimed from GB848409128A external-priority patent/GB8409128D0/en
Priority claimed from GB848409127A external-priority patent/GB8409127D0/en
Priority claimed from GB848420381A external-priority patent/GB8420381D0/en
Priority claimed from GB848423700A external-priority patent/GB8423700D0/en
Priority claimed from GB848423701A external-priority patent/GB8423701D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8547939A0 publication Critical patent/IT8547939A0/it
Publication of IT8547939A1 publication Critical patent/IT8547939A1/it
Application granted granted Critical
Publication of IT1199967B publication Critical patent/IT1199967B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT47939/85A 1984-04-09 1985-04-09 Liposomi contenenti interleucina,metodo per la loro preparazione e loro uso terapeutico nelle affezioni tumorali IT1199967B (it)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB848409125A GB8409125D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848409126A GB8409126D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848409128A GB8409128D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848409127A GB8409127D0 (en) 1984-04-09 1984-04-09 Interleukin therapy
GB848420381A GB8420381D0 (en) 1984-08-10 1984-08-10 Interleukin therapy
GB848423700A GB8423700D0 (en) 1984-09-19 1984-09-19 Interleukin therapy
GB848423701A GB8423701D0 (en) 1984-09-19 1984-09-19 Interleukin therapy

Publications (3)

Publication Number Publication Date
IT8547939A0 IT8547939A0 (it) 1985-04-09
IT8547939A1 IT8547939A1 (it) 1986-10-09
IT1199967B true IT1199967B (it) 1989-01-05

Family

ID=27562708

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47939/85A IT1199967B (it) 1984-04-09 1985-04-09 Liposomi contenenti interleucina,metodo per la loro preparazione e loro uso terapeutico nelle affezioni tumorali

Country Status (13)

Country Link
US (1) US4863740A (it)
JP (1) JPH0665650B2 (it)
AU (1) AU4094685A (it)
CH (1) CH668554A5 (it)
DE (1) DE3512926A1 (it)
DK (1) DK155085A (it)
FR (1) FR2562421B1 (it)
GB (1) GB2157172B (it)
IL (1) IL74835A0 (it)
IT (1) IT1199967B (it)
LU (1) LU85839A1 (it)
NL (1) NL8501010A (it)
SE (1) SE8501709L (it)

Families Citing this family (46)

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EP0274219A3 (en) * 1986-12-04 1988-08-03 Takeda Chemical Industries, Ltd. Interleukin-2-containing liposome composition and method for the production thereof
FR2624741B1 (fr) * 1987-12-21 1991-06-28 Pasteur Institut Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire
US5258499A (en) * 1988-05-16 1993-11-02 Vestar, Inc. Liposome targeting using receptor specific ligands
EP0577146A3 (en) * 1988-05-16 1994-02-02 NeXstar Pharmaceuticals, Inc. Liposomes coupled to hormones
EP0366770B1 (en) * 1988-05-16 1994-02-09 Vestar, Inc. Liposomes coupled to hormones
EP0440742B1 (en) * 1988-10-27 1997-01-15 The Regents Of The University Of Minnesota Liposome immunoadjuvants containing il-2
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
ATE136211T1 (de) * 1989-06-23 1996-04-15 Liposome Co Inc Zielliposomen und verfahren zur kupplung von liposomen-proteinen
JPH0363298A (ja) * 1989-07-31 1991-03-19 Green Cross Corp:The コロニー形成刺激因子・脂質複合体
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5268454A (en) 1991-02-08 1993-12-07 La Jolla Pharmaceutical Company Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5817333A (en) * 1991-10-31 1998-10-06 Fujisawa Pharmaceutical Co., Ltd. Liposome preparation containing a tricyclic compound
JPH07502734A (ja) * 1991-12-31 1995-03-23 ザイモジェネティクス，インコーポレイティド 血液損失を減少する方法および組成物
US5229109A (en) * 1992-04-14 1993-07-20 Board Of Regents, The University Of Texas System Low toxicity interleukin-2 analogues for use in immunotherapy
SI9300468A (en) * 1992-10-14 1994-06-30 Hoffmann La Roche Injectable composition for the sustained release of biologically active compounds
US5449663A (en) * 1993-06-11 1995-09-12 Bicher; Haim I. Antineoplastic compositions
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6033645A (en) * 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
US6406689B1 (en) 1995-10-03 2002-06-18 Frank W. Falkenberg Compositions and methods for treatment of tumors and metastatic diseases
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US6416740B1 (en) * 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US6339068B1 (en) 1997-05-20 2002-01-15 University Of Iowa Research Foundation Vectors and methods for immunization or therapeutic protocols
DE69829995T2 (de) * 1997-12-01 2006-02-23 Fang, Fang, San Diego Multivalente rekombinante antikörper zur behandlung von hrv infektionen
US20010003580A1 (en) * 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
AU756570B2 (en) * 1998-01-16 2003-01-16 Biomira Inc. Lipomatrix preparation
DK1105096T3 (da) 1998-08-19 2004-03-08 Skyepharma Canada Inc Injicerbare vandige propofoldispersioner
US20030035798A1 (en) * 2000-08-16 2003-02-20 Fang Fang Humanized antibodies
CA2403205A1 (en) 2000-03-13 2001-09-20 Engene, Inc. Compositions and methods of regulated protein expression in gut endocrine k cells
WO2001070763A1 (en) * 2000-03-22 2001-09-27 The Children's Hospital Of Philadelphia Modified blood clotting factors and methods of use
CA2898314A1 (en) 2001-07-19 2003-07-31 Perian Therapeutics, Inc. Multimeric proteins and methods of making and using same
US20030044354A1 (en) * 2001-08-16 2003-03-06 Carpenter Alan P. Gas microsphere liposome composites for ultrasound imaging and ultrasound stimulated drug release
TWI461436B (zh) 2005-11-25 2014-11-21 Kyowa Hakko Kirin Co Ltd 人類ｃｄ１３４（ｏｘ４０）之人類單株抗體及其製造及使用方法
EP1795540A1 (en) 2005-11-30 2007-06-13 Imaxio Multimeric complexes of antigens and an adjuvant
EP2015785A4 (en) * 2006-04-24 2009-07-15 Shantha West Inc ANTIGEN AGRM2
EP2101813B1 (en) 2006-11-27 2014-04-02 Patrys Limited Novel glycosylated peptide target in neoplastic cells
EP2417984B1 (en) 2009-04-10 2016-03-30 Kyowa Hakko Kirin Co., Ltd. Method for treatment of blood tumor using anti-tim-3 antibody
CN104558179A (zh) 2009-04-27 2015-04-29 协和发酵麒麟株式会社 用于治疗血液肿瘤的抗IL-3Rα抗体
WO2011060233A1 (en) 2009-11-11 2011-05-19 The Trustees Of The University Of Pennsylvania Anti-tem1 antibodies and uses thereof
WO2013162748A1 (en) 2012-04-27 2013-10-31 The Trustees Of The University Of Pennsylvania Anti-tumor endothelial marker-1 (tem1) antibody variants and uses thereof
US9790269B2 (en) 2013-02-08 2017-10-17 Misfolding Diagnostics, Inc. Transthyretin antibodies and uses thereof
US20160152952A1 (en) 2013-06-25 2016-06-02 Temple University-Of The Commonwealth System Of Higher Education Cortical Bone-Derived Stem Cells

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JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
GB1578776A (en) * 1976-06-10 1980-11-12 Univ Illinois Hemoglobin liposome and method of making the same
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4377567A (en) * 1978-10-02 1983-03-22 The Procter & Gamble Company Lipid membrane drug delivery
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
JPS56127308A (en) * 1980-03-11 1981-10-06 Green Cross Corp:The Blood-coagulation factor 8 pharmaceutical
EP0088046B1 (de) * 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
JPH0751511B2 (ja) * 1982-03-15 1995-06-05 味の素株式会社 インターロイキン２を含有してなる癌治療剤
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
AU564876B2 (en) * 1982-03-29 1987-08-27 Liposome Company, Inc., The Stable plurilamellar vesicles
AU573193B2 (en) * 1982-11-23 1988-06-02 Bio-Response Inc. Method for isolating cells
WO1985000606A1 (en) * 1983-07-19 1985-02-14 Takeda Chemical Industries, Ltd. Human il-2 and process for its preparation
US4464461A (en) * 1983-07-22 1984-08-07 Eastman Kodak Company Development of light-sensitive quinone diazide compositions
US4764359A (en) * 1984-05-25 1988-08-16 Lemelson Jerome H Drug compositions and their use in treating human or other mammalian patients
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids

Also Published As

Publication number Publication date
IT8547939A1 (it) 1986-10-09
GB8508809D0 (en) 1985-05-09
SE8501709L (sv) 1985-10-10
DE3512926A1 (de) 1985-10-24
FR2562421A1 (fr) 1985-10-11
DK155085D0 (da) 1985-04-03
AU4094685A (en) 1985-10-17
IT8547939A0 (it) 1985-04-09
FR2562421B1 (fr) 1989-02-17
JPS60243022A (ja) 1985-12-03
US4863740A (en) 1989-09-05
GB2157172A (en) 1985-10-23
DK155085A (da) 1985-10-10
NL8501010A (nl) 1985-11-01
GB2157172B (en) 1988-12-29
CH668554A5 (de) 1989-01-13
JPH0665650B2 (ja) 1994-08-24
LU85839A1 (fr) 1985-12-16
IL74835A0 (en) 1985-07-31
SE8501709D0 (sv) 1985-04-04

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970421