FR09C0040I1 - - Google Patents

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Publication number
FR09C0040I1
FR09C0040I1 FR09C0040C FR09C0040I1 FR 09C0040 I1 FR09C0040 I1 FR 09C0040I1 FR 09C0040 C FR09C0040 C FR 09C0040C FR 09C0040 I1 FR09C0040 I1 FR 09C0040I1
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FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20085522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR09C0040(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of FR09C0040I1 publication Critical patent/FR09C0040I1/fr
Application granted granted Critical
Publication of FR09C0040I2 publication Critical patent/FR09C0040I2/fr
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18Dibenzazepines; Hydrogenated dibenzazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR09C0040C 1995-06-30 2009-08-26 Active FR09C0040I2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT101732A PT101732B (pt) 1995-06-30 1995-06-30 Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso

Publications (2)

Publication Number Publication Date
FR09C0040I1 true FR09C0040I1 (fr) 2009-10-30
FR09C0040I2 FR09C0040I2 (fr) 2011-04-01

Family

ID=20085522

Family Applications (1)

Application Number Title Priority Date Filing Date
FR09C0040C Active FR09C0040I2 (fr) 1995-06-30 2009-08-26

Country Status (22)

Country Link
US (1) US5753646A (fr)
EP (1) EP0751129B3 (fr)
JP (2) JP3852984B2 (fr)
KR (1) KR100376603B1 (fr)
CN (1) CN1070853C (fr)
AR (1) AR003962A1 (fr)
AT (1) ATE173468T3 (fr)
AU (1) AU705388B2 (fr)
BR (1) BRPI9602933B8 (fr)
CA (1) CA2180301C (fr)
DE (2) DE122009000049I2 (fr)
DK (1) DK0751129T6 (fr)
ES (1) ES2124612T7 (fr)
FR (1) FR09C0040I2 (fr)
HU (1) HU221382B1 (fr)
NL (1) NL300406I1 (fr)
PL (1) PL185476B1 (fr)
PT (1) PT101732B (fr)
RU (1) RU2168502C2 (fr)
SI (1) SI0751129T1 (fr)
TR (1) TR199701734T1 (fr)
WO (1) WO1997002250A1 (fr)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9930058D0 (en) 1999-12-20 2000-02-09 Novartis Ag Organic compounds
GB0111566D0 (en) 2001-05-11 2001-07-04 Portela & Ca Sa Method for preparation of (s)-(+)-and (r)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azephine-5-carboxamide
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
WO2003042182A1 (fr) * 2001-11-12 2003-05-22 Novartis Ag Utilisation de monohydroxycarbamazepine pour preparer un medicament destine au traitement de troubles affectifs et de l'attention et de douleurs neuropathiques
WO2004014391A1 (fr) * 2002-08-06 2004-02-19 Novartis Ag Utilisation de carboxamides pour le traitement des acouphenes
GB0223224D0 (en) * 2002-10-07 2002-11-13 Novartis Ag Organic compounds
GB0303613D0 (en) * 2003-02-17 2003-03-19 Novartis Ag Use of organic compounds
MXPA05008729A (es) * 2003-02-17 2005-09-20 Novartis Ag Uso de s-10-hidroxi-10, 11-dihidro-carbamazepina para el tratamiento de ansiedad y trastornos bipolares.
TW200501962A (en) * 2003-04-01 2005-01-16 Novartis Ag Use of carbamazepine derivatives for the treatment of agitation in dementia patients
TW200502222A (en) 2003-04-02 2005-01-16 Novartis Ag Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders
GB2401605A (en) * 2003-05-12 2004-11-17 Portela & Ca Sa Method for racemisation of (S)-(+)- and (R)-(-)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide and optically enriched mixtures thereof
GB2416167A (en) * 2004-07-13 2006-01-18 Portela & Ca Sa Chiral inversion and esterification of (S)- and (R)-10-hydroxy-dibenzazepine carboxamides
ITMI20042230A1 (it) * 2004-11-19 2005-02-19 Farchemia Srl Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
GB2422149A (en) * 2005-01-14 2006-07-19 Portela & Ca Sa Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
AU2005331690C1 (en) * 2005-05-06 2013-01-17 Bial-Portela & Ca, S.A. Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
WO2006121363A1 (fr) * 2005-05-06 2006-11-16 Portela & C.A., S.A. Acetate d’eslicarbazepine et procedes d’utilisation
GB0515690D0 (en) 2005-07-29 2005-09-07 Portela & Ca Sa Asymmetric catalytic reduction
GB0517740D0 (en) * 2005-08-31 2005-10-12 Novartis Ag Organic compounds
GB0603008D0 (en) * 2006-02-14 2006-03-29 Portela & Ca Sa Method
GB2437078A (en) * 2006-04-11 2007-10-17 Portela & Ca Sa 10-Acyloxy-5H-dibenzo[b,f]azepine-5-carboxamides & their asymmetric hydrogenation to the chiral 10,11-dihydro derivatives
GB0700773D0 (en) * 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
US8372431B2 (en) 2007-10-26 2013-02-12 Bial-Portela & C.A., S.A. Pharmaceutical composition comprising licarbazepine acetate
US20120022047A1 (en) 2009-04-02 2012-01-26 Glenmark Generics Ltd Process for the purification of eslicarbazepine acetate
WO2011014084A1 (fr) * 2009-07-27 2011-02-03 Bial - Portela & Ca., S.A. Utilisation de dérivés de 5h-dibenz / b, f/ azépine-5-carboxamide pour le traitement de la fibromyalgie
WO2011045648A2 (fr) 2009-10-12 2011-04-21 Matrix Laboratories Limited Procédé de préparation de (s)-(-)-10-acétoxy-10,11-dihydro-5h-dibenz[b,f]azépine-5-carboxamide et ses esters
WO2011091131A2 (fr) * 2010-01-23 2011-07-28 Dr. Reddy's Laboratories Ltd. Acétate d'eslicarbazépine et ses polymorphes
WO2011117885A1 (fr) * 2010-03-23 2011-09-29 Intas Pharmaceuticals Limited Procédé de préparation d'énantiomères de licarbazépine
EP2383261B1 (fr) 2010-04-23 2013-09-04 Euticals GmbH Procédé d'hydrogénation asymétrique de cétones
WO2011138795A2 (fr) * 2010-05-03 2011-11-10 Msn Laboratories Limited Procédé amélioré de préparation de (s)-10-acétoxy-10,11-dihydro-5h-dibenz[b,f]azépine-5-carboxamide
UA115420C2 (uk) 2010-12-31 2017-11-10 Біал-Портела Енд Ка., С.А. Тверда фармацевтична композиція у формі гранул, що містить езлікарбазепіну ацетат
WO2012121701A1 (fr) * 2011-03-07 2012-09-13 Watson Laboratories, Inc. Procédé de résolution racémique (±)-10,11-dihydro -10-hydroxy -5 h-dibenz / b, f / azépine -5-carboxamide
EP2683691B1 (fr) 2011-03-08 2018-06-06 Jubilant Life Sciences Limited PROCÉDÉ DE PRÉPARATION DU (S)-(+)-10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ[b,f]AZÉPINE-5-CARBOXAMIDE ET DE SES ESTERS PAR RÉDUCTION ÉNANTIOSÉLECTIVE DU 10,11-DIHYDRO-10-OXO-5H-DIBENZ[b,f]AZÉPINE-5-CARBOXAMIDE
EP2697662B1 (fr) 2011-04-13 2018-06-06 Codexis, Inc. Procédé biocatalytique permettant de préparer de l'eslicarbazépine et ses analogues
WO2013008194A2 (fr) 2011-07-13 2013-01-17 Ranbaxy Laboratories Limited Procédé de préparation et de purification d'acétate d'eslicarbazépine et de ses intermédiaires
RU2639120C2 (ru) 2011-08-26 2017-12-19 Биал-Портела Энд Ка, С.А. Лечение с использованием ацетата эсликарбазепина или эсликарбазепина
CA2872975A1 (fr) * 2012-05-07 2013-11-14 Cellixbio Private Limited Compositions et methodes de traitement de troubles neurologiques
WO2014049550A1 (fr) 2012-09-26 2014-04-03 Ranbaxy Laboratories Limited Procédé de préparation d'oxcarbazépine et son utilisation en tant qu'intermédiaire dans la préparation d'acétate d'eslicarbazépine
EP3240779B1 (fr) * 2014-09-26 2020-10-28 Cellixbio Private Limited Compositions et méthodes de traitement de l'épilepsie et de troubles neurologiques
CN105384689B (zh) * 2014-12-24 2017-10-31 开封制药(集团)有限公司 一种改进的醋酸艾司利卡西平的合成方法
EP3064490A1 (fr) 2015-03-06 2016-09-07 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Procédé amélioré pour la préparation d'eslicarbazépine et d'acétate d'eslicarbazépine
CN105130899A (zh) * 2015-08-25 2015-12-09 安徽省新星药物开发有限责任公司 一种醋酸艾司利卡西平的合成方法
US10918604B2 (en) 2015-12-18 2021-02-16 Jubilant Generics Limited Solid oral dosage forms of eslicarbazepine
CN106588773B (zh) * 2016-11-10 2019-09-27 北京现代药物代谢研究院 一种脑靶向艾司利卡西平酯类前药及其应用
BR112021005955A2 (pt) 2018-09-28 2021-07-27 Griffith University agentes e métodos para modular atividade de patógeno

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
CH505101A (de) * 1969-03-31 1971-03-31 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) * 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
CH649080A5 (de) * 1981-04-16 1985-04-30 Ciba Geigy Ag 5h-dibenz(b,f)azepin-5-carboxamide als mittel zur prophylaxe und behandlung von zerebraler leistungsinsuffizienz.
DD218889B3 (de) * 1983-11-09 1992-11-05 Dresden Arzneimittel Verfahren zur herstellung neuer 5-carbamoyl-10,11-dihydro-5h-dibenz|b,f¨azepine
US5466683A (en) * 1994-08-25 1995-11-14 Teva Pharmaceutical Industries Ltd. Water-soluble analogs of carbamazepine

Also Published As

Publication number Publication date
DK0751129T6 (da) 2020-05-25
DE122009000049I1 (de) 2010-01-21
HUP9900172A2 (hu) 1999-04-28
ES2124612B5 (fr) 2019-01-28
FR09C0040I2 (fr) 2011-04-01
PT101732A (pt) 1997-01-31
TR199701734T1 (xx) 1998-04-21
JP3852984B2 (ja) 2006-12-06
CA2180301A1 (fr) 1996-12-31
PL185476B1 (pl) 2003-05-30
DK0751129T3 (da) 1999-08-02
BR9602933A (pt) 1998-04-28
CN1193965A (zh) 1998-09-23
AU6310696A (en) 1997-02-05
CA2180301C (fr) 2004-02-10
EP0751129B3 (fr) 2020-05-13
BRPI9602933B8 (pt) 2022-01-18
DE69600985T2 (de) 1999-04-15
DE122009000049I2 (de) 2011-01-13
JP2004256516A (ja) 2004-09-16
KR19990028464A (ko) 1999-04-15
RU2168502C2 (ru) 2001-06-10
AU705388B2 (en) 1999-05-20
EP0751129B1 (fr) 1998-11-18
HUP9900172A3 (en) 1999-11-29
DE69600985T3 (de) 2020-09-24
PL324313A1 (en) 1998-05-25
US5753646A (en) 1998-05-19
SI0751129T1 (en) 1999-02-28
ES2124612T3 (es) 1999-02-01
CN1070853C (zh) 2001-09-12
EP0751129A1 (fr) 1997-01-02
HU221382B1 (en) 2002-09-28
DE69600985D1 (de) 1998-12-24
KR100376603B1 (ko) 2003-12-18
WO1997002250A1 (fr) 1997-01-23
ES2124612T7 (es) 2020-07-20
JPH09110836A (ja) 1997-04-28
NL300406I1 (nl) 2009-11-02
ATE173468T3 (de) 1998-12-15
BR9602933B1 (pt) 2013-06-11
AR003962A1 (es) 1998-09-30
PT101732B (pt) 1997-12-31

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