FI97385B - Optiskt aktiva mellanprodukter vilka är användbara vid framställning av 2R-bensylkroman-6-karbaldehyd - Google Patents

Optiskt aktiva mellanprodukter vilka är användbara vid framställning av 2R-bensylkroman-6-karbaldehyd Download PDF

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Publication number
FI97385B
FI97385B FI911356A FI911356A FI97385B FI 97385 B FI97385 B FI 97385B FI 911356 A FI911356 A FI 911356A FI 911356 A FI911356 A FI 911356A FI 97385 B FI97385 B FI 97385B
Authority
FI
Finland
Prior art keywords
chroman
benzylchroman
optically active
carbaldehyde
mol
Prior art date
Application number
FI911356A
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English (en)
Finnish (fi)
Other versions
FI911356A (sv
FI97385C (sv
FI911356A0 (sv
Inventor
Frank John Urban
Original Assignee
Pfizer
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Publication date
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Application filed by Pfizer filed Critical Pfizer
Publication of FI911356A0 publication Critical patent/FI911356A0/sv
Publication of FI911356A publication Critical patent/FI911356A/sv
Publication of FI97385B publication Critical patent/FI97385B/sv
Application granted granted Critical
Publication of FI97385C publication Critical patent/FI97385C/sv

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI911356A 1990-03-21 1991-03-20 Optiskt aktiva mellanprodukter vilka är användbara vid framställning av 2R-bensylkroman-6-karbaldehyd FI97385C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49673790 1990-03-21
US07/496,737 US5089637A (en) 1990-03-21 1990-03-21 Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde

Publications (4)

Publication Number Publication Date
FI911356A0 FI911356A0 (sv) 1991-03-20
FI911356A FI911356A (sv) 1991-09-22
FI97385B true FI97385B (sv) 1996-08-30
FI97385C FI97385C (sv) 1996-12-10

Family

ID=23973911

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911356A FI97385C (sv) 1990-03-21 1991-03-20 Optiskt aktiva mellanprodukter vilka är användbara vid framställning av 2R-bensylkroman-6-karbaldehyd

Country Status (20)

Country Link
US (1) US5089637A (sv)
EP (1) EP0448254B1 (sv)
JP (1) JPH0764838B2 (sv)
KR (1) KR940005601B1 (sv)
AT (1) ATE117299T1 (sv)
AU (1) AU620756B2 (sv)
CA (1) CA2038610C (sv)
DE (1) DE69106753T2 (sv)
DK (1) DK0448254T3 (sv)
ES (1) ES2067148T3 (sv)
FI (1) FI97385C (sv)
GR (1) GR3015390T3 (sv)
HU (1) HUT61603A (sv)
IE (1) IE64066B1 (sv)
IL (1) IL97549A0 (sv)
MY (1) MY106374A (sv)
NO (1) NO179680C (sv)
NZ (1) NZ237466A (sv)
PT (1) PT97070B (sv)
ZA (1) ZA912063B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658796A (en) * 1995-06-07 1997-08-19 Seprachem, Inc. Optical resolution of alkyl chroman-2-carboxylates
US6184005B1 (en) 1998-04-28 2001-02-06 Novo Nordisk A/S Enzymatic resolvation for obtaining a (−)-3,4-trans-diarylchroman
JP2002512807A (ja) * 1998-04-28 2002-05-08 ノボ ノルディスク アクティーゼルスカブ （−）−３．４−トランス−ジアリールクロマンを得るための酵素的分割
EP1445324A4 (en) * 2001-11-09 2005-02-16 Kaneka Corp PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE PRODUCT
US20060141591A1 (en) * 2003-06-04 2006-06-29 Youichi Kyuuko Method for producing optically active chroman-carboxylate
PE20061297A1 (es) * 2005-04-22 2006-12-24 Wyeth Corp Compuestos derivados de cromano y cromeno moduladores del receptor de serotonina 5-ht2c
KR100784850B1 (ko) * 2006-10-19 2007-12-14 충북대학교 산학협력단 크로만-2-카복실산 아릴아마이드 유도체, 그 제조방법 및이를 포함하는 ＮＦ-κＢ 저해제
IT1402974B1 (it) 2010-11-30 2013-09-27 Menarini Int Operations Lu Sa Processo per la preparazione del nebivololo.
FR2986804A1 (fr) * 2012-02-09 2013-08-16 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels
US10010266B2 (en) 2013-03-15 2018-07-03 Airway Control Technologies, Llc Medical breathing apparatus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654362A (en) * 1983-12-05 1987-03-31 Janssen Pharmaceutica, N.V. Derivatives of 2,2'-iminobisethanol
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
WO1986007056A1 (en) * 1985-05-21 1986-12-04 Pfizer Inc. Hypoglycemic thiazolidinediones
US5037747A (en) * 1988-01-26 1991-08-06 Hoffmann-La Roche Inc. Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis

Also Published As

Publication number Publication date
PT97070B (pt) 2001-05-31
GR3015390T3 (en) 1995-06-30
ATE117299T1 (de) 1995-02-15
HU910939D0 (en) 1991-10-28
ES2067148T3 (es) 1995-03-16
FI911356A (sv) 1991-09-22
NZ237466A (en) 1992-04-28
MY106374A (en) 1995-05-30
PT97070A (pt) 1991-10-31
US5089637A (en) 1992-02-18
IL97549A0 (en) 1992-06-21
DE69106753D1 (de) 1995-03-02
IE910938A1 (en) 1991-09-25
JPH04234871A (ja) 1992-08-24
EP0448254A2 (en) 1991-09-25
AU620756B2 (en) 1992-02-20
EP0448254B1 (en) 1995-01-18
CA2038610C (en) 1999-03-09
CA2038610A1 (en) 1991-09-22
KR940005601B1 (ko) 1994-06-21
KR910016939A (ko) 1991-11-05
ZA912063B (en) 1992-10-28
NO179680B (no) 1996-08-19
JPH0764838B2 (ja) 1995-07-12
DK0448254T3 (da) 1995-03-20
FI97385C (sv) 1996-12-10
FI911356A0 (sv) 1991-03-20
NO179680C (no) 1996-11-27
DE69106753T2 (de) 1995-05-18
NO911101D0 (no) 1991-03-19
NO911101L (no) 1991-09-23
AU7369691A (en) 1991-11-14
EP0448254A3 (en) 1991-12-18
IE64066B1 (en) 1995-07-12
HUT61603A (en) 1993-01-28

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