FI973466A - Soluimmuniteetin suuntaaminen uudelleen proteiinityrosiinikinaasikimeerojen avulla - Google Patents

Soluimmuniteetin suuntaaminen uudelleen proteiinityrosiinikinaasikimeerojen avulla Download PDF

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Publication number
FI973466A
FI973466A FI973466A FI973466A FI973466A FI 973466 A FI973466 A FI 973466A FI 973466 A FI973466 A FI 973466A FI 973466 A FI973466 A FI 973466A FI 973466 A FI973466 A FI 973466A
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Prior art keywords
cell
infective agent
protein
tyrosine kinase
receptor
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FI973466A
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English (en)
Swedish (sv)
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FI973466A0 (fi
FI121012B (fi
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Brian Seed
Charles Romeo
Waldemar Kolanus
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Gen Hospital Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI973466A 1995-02-24 1997-08-22 T-lymfosyytteja sisältävä lääkeaine soluimmuniteetin suuntaamiseen uudelleen proteiinityrosiinikinaasikimeerojen avulla FI121012B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39417795 1995-02-24
US08/394,177 US5912170A (en) 1991-03-07 1995-02-24 Redirection of cellular immunity by protein-tyrosine kinase chimeras
PCT/US1996/001001 WO1996026265A1 (en) 1995-02-24 1996-01-24 Redirection of cellular immunity by protein-tyrosine kinase chimeras
US9601001 1996-01-24

Publications (3)

Publication Number Publication Date
FI973466A true FI973466A (fi) 1997-08-22
FI973466A0 FI973466A0 (fi) 1997-08-22
FI121012B FI121012B (fi) 2010-06-15

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FI973466A FI121012B (fi) 1995-02-24 1997-08-22 T-lymfosyytteja sisältävä lääkeaine soluimmuniteetin suuntaamiseen uudelleen proteiinityrosiinikinaasikimeerojen avulla

Country Status (19)

Country Link
US (3) US5912170A (fi)
EP (1) EP0812352B1 (fi)
JP (1) JP4170389B2 (fi)
KR (1) KR100454396B1 (fi)
AT (1) ATE323755T1 (fi)
AU (1) AU703125C (fi)
CA (1) CA2209301C (fi)
CZ (1) CZ294909B6 (fi)
DE (1) DE69636053T2 (fi)
DK (1) DK0812352T3 (fi)
ES (1) ES2258772T3 (fi)
FI (1) FI121012B (fi)
HU (1) HU225689B1 (fi)
NO (1) NO321459B1 (fi)
NZ (2) NZ501340A (fi)
PT (1) PT812352E (fi)
RU (1) RU2225870C2 (fi)
WO (1) WO1996026265A1 (fi)
ZA (1) ZA961476B (fi)

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US6410014B1 (en) 2002-06-25
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JP4170389B2 (ja) 2008-10-22
WO1996026265A1 (en) 1996-08-29
KR19980702451A (ko) 1998-07-15
KR100454396B1 (ko) 2005-01-17
RU2225870C2 (ru) 2004-03-20
PT812352E (pt) 2006-07-31
DE69636053T2 (de) 2006-11-23
NO973863D0 (no) 1997-08-22
NZ501340A (en) 2004-12-24
FI973466A0 (fi) 1997-08-22
US20020176851A1 (en) 2002-11-28
DE69636053D1 (de) 2006-05-24
NO973863L (no) 1997-10-22
HU225689B1 (en) 2007-06-28
HUP9800459A3 (en) 2001-01-29
EP0812352A1 (en) 1997-12-17
CZ294909B6 (cs) 2005-04-13
NZ302090A (en) 2000-01-28
CZ260197A3 (cs) 1998-05-13
CA2209301C (en) 2010-11-23
ES2258772T3 (es) 2006-09-01
NO321459B1 (no) 2006-05-15
EP0812352B1 (en) 2006-04-19
ATE323755T1 (de) 2006-05-15
EP0812352A4 (en) 2000-09-13
AU703125C (en) 2004-11-25
AU703125B2 (en) 1999-03-18
US5912170A (en) 1999-06-15
HUP9800459A2 (hu) 1998-06-29
FI121012B (fi) 2010-06-15
CA2209301A1 (en) 1996-08-29
AU4767596A (en) 1996-09-11

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