FI973402A0 - Nya proteiner och förfaranden för producering av proteinerna - Google Patents

Nya proteiner och förfaranden för producering av proteinerna

Info

Publication number
FI973402A0
FI973402A0 FI973402A FI973402A FI973402A0 FI 973402 A0 FI973402 A0 FI 973402A0 FI 973402 A FI973402 A FI 973402A FI 973402 A FI973402 A FI 973402A FI 973402 A0 FI973402 A0 FI 973402A0
Authority
FI
Finland
Prior art keywords
protein
proteins
producing
antibodies
processes
Prior art date
Application number
FI973402A
Other languages
English (en)
Finnish (fi)
Other versions
FI973402A (sv
Inventor
Masaaki Goto
Eisuke Tsuda
Shin Ichi Mochizuki
Kazuki Yano
Fumie Kobayashi
Nobuyuki Shima
Hisataka Yasuda
Nobuaki Nakagawa
Tomonori Morinaga
Masatsugu Ueda
Kanji Higashio
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Publication of FI973402A0 publication Critical patent/FI973402A0/sv
Publication of FI973402A publication Critical patent/FI973402A/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
FI973402A 1995-02-20 1997-08-20 Nya proteiner och förfaranden för producering av proteinerna FI973402A (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5497795 1995-02-20
JP20750895 1995-07-21
PCT/JP1996/000374 WO1996026217A1 (fr) 1995-02-20 1996-02-20 Proteine nouvelle et ses procedes de production

Publications (2)

Publication Number Publication Date
FI973402A0 true FI973402A0 (sv) 1997-08-20
FI973402A FI973402A (sv) 1997-10-17

Family

ID=26395808

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973402A FI973402A (sv) 1995-02-20 1997-08-20 Nya proteiner och förfaranden för producering av proteinerna

Country Status (20)

Country Link
US (9) US7125686B1 (sv)
EP (2) EP0816380B1 (sv)
JP (1) JP3502102B2 (sv)
KR (1) KR100381788B1 (sv)
CN (1) CN1218961C (sv)
AT (2) ATE391178T1 (sv)
AU (1) AU702557C (sv)
CA (1) CA2213469A1 (sv)
DE (2) DE69637486D1 (sv)
ES (1) ES2227579T3 (sv)
FI (1) FI973402A (sv)
HU (1) HU224570B1 (sv)
IL (1) IL117175A (sv)
MX (1) MX9706341A (sv)
NO (1) NO318898B1 (sv)
NZ (1) NZ301362A (sv)
PT (1) PT816380E (sv)
RU (2) RU2238948C2 (sv)
TW (1) TW538049B (sv)
WO (1) WO1996026217A1 (sv)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078493B1 (en) 1995-03-15 2006-07-18 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor-like genes
JPH11503007A (ja) * 1995-03-15 1999-03-23 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒト腫瘍壊死因子受容体
US7094564B1 (en) 1995-03-15 2006-08-22 Human Genome Sciences, Inc. Human tumor necrosis factor receptor
US8110659B1 (en) 1995-03-15 2012-02-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like genes
US7632922B1 (en) 1995-12-22 2009-12-15 Amgen, Inc. Osteoprotegerin
US6369027B1 (en) * 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin
JPH1057071A (ja) * 1996-08-19 1998-03-03 Snow Brand Milk Prod Co Ltd 新規ｄｎａ及びそれを用いた蛋白質の製造方法
WO1998012344A1 (en) * 1996-09-18 1998-03-26 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like genes
DE69738811D1 (de) * 1996-12-13 2008-08-14 Schering Corp Oberflächenantigene aus Säugern
US6271349B1 (en) 1996-12-23 2001-08-07 Immunex Corporation Receptor activator of NF-κB
DE69738841D1 (de) 1996-12-23 2008-08-28 Immunex Corp Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie
CN1138786C (zh) 1997-04-15 2004-02-18 三共株式会社 识别破骨细胞形成抑制因子结合蛋白的抗体及制备和用途
US6316408B1 (en) 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
IL132304A0 (en) 1997-04-16 2001-03-19 Amgen Inc Osteoprotegerin binding proteins and receptors
JP2002514078A (ja) * 1997-04-18 2002-05-14 ミレニアム ファーマシューティカルズ インク． Ｆｔｈｍａ−０７０関連蛋白質ファミリーおよびｔ８５関連蛋白質ファミリーの新規分子ならびにそれらの使用
EP0980432A1 (en) * 1997-05-01 2000-02-23 Amgen, Inc. Chimeric opg polypeptides
US6346388B1 (en) 1997-08-13 2002-02-12 Smithkline Beecham Corporation Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2
RU2203497C2 (ru) * 1997-09-24 2003-04-27 Санкио Компани Лимитед Способ диагностики метаболических костных заболеваний
US6297022B1 (en) 1997-10-08 2001-10-02 Smithkline Beecham Corporation Method of identifying agonists and antagonists for tumor necrosis related receptor TR1
US6087555A (en) * 1997-10-15 2000-07-11 Amgen Inc. Mice lacking expression of osteoprotegerin
JPH11155420A (ja) * 1997-12-02 1999-06-15 Snow Brand Milk Prod Co Ltd トランスジェニック動物
EP2009025B1 (en) 1998-05-14 2011-07-27 Immunex Corporation Method of inhibiting osteoclast activity
AU6006099A (en) * 1998-10-09 2000-05-01 Sankyo Company Limited Preventives or remedies for cachexia
BR9914834A (pt) * 1998-10-28 2001-08-14 Snow Brand Milk Products Co Ltd Agente de tratamento de patobolismo ósseo, e, método para intensificar a atividade de fator inibidor de osteoclastogênese
AUPQ167599A0 (en) * 1999-07-19 1999-08-12 St. Vincent's Institute Of Medical Research Inhibitor of osteoclast precursor formation
AU7720600A (en) * 1999-09-27 2001-04-30 Eli Lilly And Company Osteoprotegerin regulatory region
JP2001103964A (ja) * 1999-10-05 2001-04-17 Teijin Ltd 破骨細胞形成抑制方法または骨吸収抑制方法
WO2002062990A1 (fr) * 2001-02-07 2002-08-15 Sankyo Company, Limited Anticorps et utilisation de cet anticorps
EP1399555A2 (en) * 2001-02-09 2004-03-24 Maxygen Holdings Ltd. c/o Close Brothers (Cayman) Limited Rank ligand-binding polypeptides
CN1238379C (zh) * 2001-03-21 2006-01-25 中国科学院上海生命科学研究院 新的破骨细胞形成抑制因子、其编码序列及用途
EP1377610A2 (en) * 2001-04-03 2004-01-07 Société des Produits Nestlé S.A. Osteoprotegerin in milk
NZ529359A (en) 2001-05-25 2007-04-27 Human Genome Sciences Inc Antibodies that immunospecifically bind to a TR4 polypeptide or polypeptide fragment or variant of TR4 and their use in a medicament for treating cancer
EP1270015A3 (en) * 2001-06-29 2004-02-25 Sankyo Company Limited A complex comprising OCIF and Polysaccharide
JP4336467B2 (ja) * 2001-10-15 2009-09-30 株式会社林原生物化学研究所 破骨細胞形成抑制因子の産生を調節し得る物質のスクリーニング方法
EP1482978A1 (en) * 2002-03-01 2004-12-08 Sankyo Company, Limited Pharmaceutical composition comprising osteoclastogenesis inhibitory factor
CA2481074A1 (en) 2002-04-05 2003-10-23 Amgen Inc. Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
EP1583836A4 (en) * 2002-12-11 2006-12-27 Univ Massachusetts METHOD OF INTRODUCING siRNA IN ADIPOCYTES
US7740861B2 (en) 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
TWI364458B (en) * 2004-08-27 2012-05-21 Wyeth Res Ireland Ltd Production of tnfr-lg
JP5302537B2 (ja) 2004-09-17 2013-10-02 ユニバーシティ オブ マサチューセッツ リソソーム酵素欠損症のための組成物およびそれらの使用
JP5422203B2 (ja) * 2005-04-19 2014-02-19 キングス カレッジ ロンドン 使用
AU2006306228A1 (en) * 2005-10-24 2007-05-03 University Of Massachusetts Compositions and their uses for gene therapy of bone conditions
CA3045808C (en) * 2005-11-23 2022-08-16 Acceleron Pharma, Inc. Activin-actriia antagonists and uses for promoting bone growth
US10741034B2 (en) 2006-05-19 2020-08-11 Apdn (B.V.I.) Inc. Security system and method of marking an inventory item and/or person in the vicinity
WO2009048072A1 (ja) 2007-10-11 2009-04-16 Daiichi Sankyo Company, Limited 破骨細胞関連蛋白質Ｓｉｇｌｅｃ－１５を標的とした抗体
WO2009058913A2 (en) * 2007-10-29 2009-05-07 University Of Massachusetts Encapsulated nanoparticles for nucleic acid delivery
KR101690340B1 (ko) 2009-04-09 2016-12-27 다이이찌 산쿄 가부시키가이샤 항 Ｓｉｇｌｅｃ-15 항체
EP2625205A2 (en) 2010-10-05 2013-08-14 Daiichi Sankyo Company, Limited Antibody targeting osteoclast-related protein siglec-15
CN102011025A (zh) * 2010-10-11 2011-04-13 宁波市鄞州品达电器焊料有限公司 一种耐超高温的无铅焊锡
CA2868959A1 (en) 2012-03-30 2013-10-03 Daiichi Sankyo Company, Limited Cdr-modified anti-siglec-15 antibody
US9963740B2 (en) * 2013-03-07 2018-05-08 APDN (B.V.I.), Inc. Method and device for marking articles
CA2926436A1 (en) 2013-10-07 2015-04-16 Judith Murrah Multimode image and spectral reader
US10745825B2 (en) 2014-03-18 2020-08-18 Apdn (B.V.I.) Inc. Encrypted optical markers for security applications
WO2015142990A1 (en) 2014-03-18 2015-09-24 Apdn (B.V.I.) Inc. Encryped optical markers for security applications
JP6339855B2 (ja) * 2014-05-14 2018-06-06 住友ゴム工業株式会社 エアレスタイヤ及びその製造方法
WO2017180302A1 (en) 2016-04-11 2017-10-19 Apdn (B.V.I.) Inc. Method of marking cellulosic products
US10995371B2 (en) 2016-10-13 2021-05-04 Apdn (B.V.I.) Inc. Composition and method of DNA marking elastomeric material
WO2018156352A1 (en) 2017-02-21 2018-08-30 Apdn (B.V.I) Inc. Nucleic acid coated submicron particles for authentication

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US216297A (en) * 1879-06-10 Improvement in ironing-stands
US100488A (en) * 1870-03-01 Improved tire-xjfsetting machine
US127637A (en) * 1872-06-04 Improvement in couplings for divided axles
US45456A (en) * 1864-12-13 Improved apparatus for carbureting air
US207827A (en) * 1878-09-10 Improvement in siphon-condensers
US176647A (en) * 1876-04-25 Improvement in car-couplings
US33535A (en) * 1861-10-22 Improvement in machines for making bricks
US208045A (en) * 1878-09-17 Improvement in ether-meters for refrigerating-machines
US100069A (en) * 1870-02-22 Geokge h
US104485A (en) * 1870-06-21 Improvement in sleeping-cars
US166097A (en) * 1875-07-27 Improvement in buttons for wearing apparel
US150989A (en) * 1874-05-19 Improvement in pin and dowel machines
US86826A (en) * 1869-02-09 Improvement in mechanical movement
US181418A (en) * 1876-08-22 Improvement in gas apparatus
US144480A (en) * 1873-11-11 Improvement in cutting attachments for sewing-machines
US175840A (en) * 1876-04-11 Improvement in circular-knitting machines
US103978A (en) * 1870-06-07 Improvement in bee-hives
US169117A (en) * 1875-10-26 Improvement in revolution-indicators
US81720A (en) * 1868-09-01 Isaac williams
US139325A (en) * 1873-05-27 Improvement in carriage-springs
US86827A (en) * 1869-02-09 Improved rubber boot
US886826A (en) * 1907-12-14 1908-05-05 Reece Button Hole Machine Co Button-sewing machine.
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4710473A (en) 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
WO1986000922A1 (en) 1984-07-30 1986-02-13 The Salk Institute For Biological Studies Retroviral gene transfer vectors
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
JP2604135B2 (ja) 1986-02-28 1997-04-30 ライオン株式会社 口腔骨疾患治療剤
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
WO1990004417A1 (en) * 1988-10-24 1990-05-03 Bruce Caterson Methods of and compositions for diagnosing, monitoring and treating the early stages of osteoarthritis
JP2877509B2 (ja) 1989-05-19 1999-03-31 アムジエン・インコーポレーテツド メタロプロテイナーゼ阻害剤
JP3356775B2 (ja) 1990-11-30 2002-12-16 セルトリックス ファーマシューティカルズ， インコーポレイテッド ＴＧＦ―βとの共同的組合せによる骨修復のための骨形成タンパク質の使用
US5118667A (en) 1991-05-03 1992-06-02 Celtrix Pharmaceuticals, Inc. Bone growth factors and inhibitors of bone resorption for promoting bone formation
CA2068389A1 (en) 1991-05-13 1992-11-14 Masahiko Sato Method for inhibiting bone resorption
TW318142B (sv) * 1991-06-03 1997-10-21 Mitsubishi Chemicals Co Ltd
MX9204303A (es) 1991-07-23 1993-11-01 Rhone Poulenc Rorer Int Factor regulador del crecimiento de osteoclasto.
IL99120A0 (en) 1991-08-07 1992-07-15 Yeda Res & Dev Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them
US5366859A (en) * 1991-10-31 1994-11-22 Mitsubishi Petrochemical Co., Ltd. Radioimmunoassay method
CA2124967C (en) 1991-12-17 2008-04-08 Nils Lonberg Transgenic non-human animals capable of producing heterologous antibodies
US5447851B1 (en) 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
US5427954A (en) * 1992-04-29 1995-06-27 Shriner's Hospitals For Crippled Children Compositions and methods for detection and treatment of human osteoarthritis
DK0639079T3 (da) 1992-04-30 2000-06-13 Amgen Inc Fremgangsmåder til behandling af interleukin-1- og tumornekrosefaktor-medierede sygdomme
US5585479A (en) 1992-07-24 1996-12-17 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ELAM-I RNA
US5578569A (en) 1993-03-12 1996-11-26 Tam; Cherk S. Method of increasing bone growth
US5457035A (en) 1993-07-23 1995-10-10 Immunex Corporation Cytokine which is a ligand for OX40
ES2157991T3 (es) 1993-09-14 2001-09-01 Merck & Co Inc Cadn que codifica una nueva proteina humana, la tirosin-fosfatasa.
US6268212B1 (en) 1993-10-18 2001-07-31 Amgen Inc. Tissue specific transgene expression
AU2753595A (en) * 1994-06-27 1996-01-19 Snow Brand Milk Products Co., Ltd. Novel protein and process for producing the same
EP0727211A1 (en) 1995-02-10 1996-08-21 Smithkline Beecham Corporation Use of src SH2 specific compounds to treat a bone resorption disease
US6001349A (en) 1995-02-22 1999-12-14 Therion Biologics Corporation Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof
WO1996028546A1 (en) * 1995-03-15 1996-09-19 Human Genome Sciences, Inc. Human tumor necrosis factor receptor
US7094564B1 (en) * 1995-03-15 2006-08-22 Human Genome Sciences, Inc. Human tumor necrosis factor receptor
US20030166097A1 (en) 1995-03-15 2003-09-04 Human Genome Sciences, Inc. Human tumor necrosis factor receptor
WO1997000317A1 (en) 1995-06-07 1997-01-03 Osteosa Inc. Osteoclast growth regulatory factor
WO1997000318A1 (en) 1995-06-07 1997-01-03 Osteosa Inc. Osteoclast growth regulatory factor
US5843901A (en) 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
US20030207827A1 (en) 1995-12-22 2003-11-06 William J. Boyle Osteoprotegerin
US6613544B1 (en) 1995-12-22 2003-09-02 Amgen Inc. Osteoprotegerin
US6369027B1 (en) * 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin
JPH1057071A (ja) 1996-08-19 1998-03-03 Snow Brand Milk Prod Co Ltd 新規ｄｎａ及びそれを用いた蛋白質の製造方法
US5830850A (en) * 1996-08-28 1998-11-03 Mount Sinai School Of Medicine Of The City Of New York Methods for the treatment of bone resorption disorders, including osteoporosis
DE69738811D1 (de) 1996-12-13 2008-08-14 Schering Corp Oberflächenantigene aus Säugern
EP0951546A2 (en) 1996-12-20 1999-10-27 The Board Of Regents, The University Of Texas System Compositions and methods of use for osteoclast inhibitory factors
DE69738841D1 (de) * 1996-12-23 2008-08-28 Immunex Corp Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie
US6271349B1 (en) * 1996-12-23 2001-08-07 Immunex Corporation Receptor activator of NF-κB
CN1138786C (zh) 1997-04-15 2004-02-18 三共株式会社 识别破骨细胞形成抑制因子结合蛋白的抗体及制备和用途
US6316408B1 (en) 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
IL132304A0 (en) 1997-04-16 2001-03-19 Amgen Inc Osteoprotegerin binding proteins and receptors
US5843678A (en) 1997-04-16 1998-12-01 Amgen Inc. Osteoprotegerin binding proteins
US6656508B2 (en) 1997-04-17 2003-12-02 Amgen Inc. Sustained-release alginate gels
EP0980432A1 (en) 1997-05-01 2000-02-23 Amgen, Inc. Chimeric opg polypeptides
WO1998054201A1 (en) 1997-05-29 1998-12-03 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like protein 8
RU2203497C2 (ru) 1997-09-24 2003-04-27 Санкио Компани Лимитед Способ диагностики метаболических костных заболеваний
US6297022B1 (en) * 1997-10-08 2001-10-02 Smithkline Beecham Corporation Method of identifying agonists and antagonists for tumor necrosis related receptor TR1
US6087555A (en) 1997-10-15 2000-07-11 Amgen Inc. Mice lacking expression of osteoprotegerin
US6790823B1 (en) 1998-04-23 2004-09-14 Amgen Inc. Compositions and methods for the prevention and treatment of cardiovascular diseases
EP2009025B1 (en) 1998-05-14 2011-07-27 Immunex Corporation Method of inhibiting osteoclast activity
BR9914834A (pt) 1998-10-28 2001-08-14 Snow Brand Milk Products Co Ltd Agente de tratamento de patobolismo ósseo, e, método para intensificar a atividade de fator inibidor de osteoclastogênese
WO2001003719A2 (en) 1999-07-09 2001-01-18 Amgen Inc. Combination therapy for conditions leading to bone loss
KR20010085996A (ko) 1999-09-03 2001-09-07 스티븐 엠. 오드레 암 및 암관련 골손실을 예방 또는 치료하는 조성물 및 방법
US20030144187A1 (en) 1999-09-03 2003-07-31 Colin R. Dunstan Opg fusion protein compositions and methods
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
CA2451955C (en) 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
EP1270015A3 (en) 2001-06-29 2004-02-25 Sankyo Company Limited A complex comprising OCIF and Polysaccharide
EP1482978A1 (en) 2002-03-01 2004-12-08 Sankyo Company, Limited Pharmaceutical composition comprising osteoclastogenesis inhibitory factor
JP2009521229A (ja) 2005-12-23 2009-06-04 ジェイ．クレイグ ベンター インスティチュート 細胞又は細胞様システムへのゲノム若しくは部分ゲノムのインストール

Also Published As

Publication number Publication date
US7125686B1 (en) 2006-10-24
CN1175956A (zh) 1998-03-11
NO973801D0 (no) 1997-08-19
US20050026837A1 (en) 2005-02-03
NO318898B1 (no) 2005-05-18
EP1528103A1 (en) 2005-05-04
TW538049B (en) 2003-06-21
ATE391178T1 (de) 2008-04-15
ATE274580T1 (de) 2004-09-15
JP3502102B2 (ja) 2004-03-02
ES2227579T3 (es) 2005-04-01
IL117175A0 (en) 1996-06-18
RU2238948C2 (ru) 2004-10-27
AU702557C (en) 2004-11-04
AU4677396A (en) 1996-09-11
US7276344B2 (en) 2007-10-02
RU2194714C2 (ru) 2002-12-20
HU224570B1 (hu) 2005-10-28
NZ301362A (en) 1999-11-29
CA2213469A1 (en) 1996-08-29
KR100381788B1 (ko) 2003-08-02
EP1528103B1 (en) 2008-04-02
IL117175A (en) 2005-11-20
HUP9900422A1 (hu) 1999-06-28
DE69633225D1 (de) 2004-09-30
US20050014229A1 (en) 2005-01-20
US20050124054A1 (en) 2005-06-09
US6855808B2 (en) 2005-02-15
EP0816380A4 (en) 1998-11-18
US20050118682A1 (en) 2005-06-02
EP0816380B1 (en) 2004-08-25
EP0816380A1 (en) 1998-01-07
WO1996026217A1 (fr) 1996-08-29
US20040142426A1 (en) 2004-07-22
KR19980702369A (ko) 1998-07-15
US7205397B2 (en) 2007-04-17
US7468268B2 (en) 2008-12-23
PT816380E (pt) 2004-12-31
RU2002120050A (ru) 2004-03-27
DE69633225T2 (de) 2005-09-01
FI973402A (sv) 1997-10-17
AU702557B2 (en) 1999-02-25
DE69637486D1 (de) 2008-05-15
US20030153048A1 (en) 2003-08-14
NO973801L (no) 1997-10-20
CN1218961C (zh) 2005-09-14
US20020051969A1 (en) 2002-05-02
US20040143859A1 (en) 2004-07-22
MX9706341A (es) 1998-08-30
HUP9900422A3 (en) 2002-11-28

Similar Documents

Publication Publication Date Title
FI973402A0 (sv) Nya proteiner och förfaranden för producering av proteinerna
HUP9900920A2 (hu) Eljárás emlőssejt-tenyészetekben termelt proteinek szializációjának szabályozására
DE69029657D1 (de) Menschliches cytokin, interleukin-9
FI844597A0 (fi) Foerfarande foer framstaellning av en synnerligen ren hyaluronsyra.
ATE318917T1 (de) Verfahren zur bakteriellen herstellung von heterologen polypeptiden mit disulfidbrücke
DE60313188D1 (de) Verfahren und medien zur kontrolle der sialysierung von proteinen, die von säugetierzellen produziert werden
ATE277078T1 (de) N-terminal modifizierte polypeptide, und herstellungsprozess
CA2066174A1 (en) Process for the enzymatic preparation of basic fibroblast growth factor
CA2066370A1 (en) Yield when disulfide-bonded proteins are secreted
DE3855084T2 (de) Herstellung und Reinigung eines Proteins, das mit einem Bindungsprotein fusioniert ist
DE69333346D1 (de) Neuartiges p- selectin ligandenprotein
US5077393A (en) Method for producing vitronectin
ATE239494T1 (de) Heparin-binding protein zur behandlung von sepsis
KR960703943A (ko) 신규단백질 및 그 제조방법
EP1070758A4 (en) NEW PROTEIN AND METHOD FOR THE PRODUCTION THEREOF
ATE91717T1 (de) Verfahren zur herstellung von proteinen in loeslicher form.
Shimada et al. A putative transcription factor binding to the upstream region of the puf operon in Rhodobacter sphaeroides
Elamrani et al. Evidence for fibronectin degradation by calpain II
Derechin Hydrolysis of some casein fractions with plasmin
FI970503A0 (sv) ICAM-4-material och metoder
Pénit et al. Purification and properties of chick terminal deoxynucleotidyl transferase (TdT)
Keski-Oja et al. Characterization of a novel gelatin-binding 21 kDa protein secreted by cultured adherent cells
DE69126379D1 (de) Verfahren zur herstellung und reinigung des carboxyterminalen fragments der dna-polymerase i von streptococcus pneumoniae
ATE250126T1 (de) Methode zur herstellung rekombinanter proteine und dafür verwendete wirtszellen
ATE153070T1 (de) Verfahren zur herstellung eines vollendeten polypeptids durch faktor-xa enzymatische spaltung