FI972240A0 - Förhindrade N-oxidestrar av rapamycin och deras användning som läkemedel - Google Patents

Förhindrade N-oxidestrar av rapamycin och deras användning som läkemedel

Info

Publication number
FI972240A0
FI972240A0 FI972240A FI972240A FI972240A0 FI 972240 A0 FI972240 A0 FI 972240A0 FI 972240 A FI972240 A FI 972240A FI 972240 A FI972240 A FI 972240A FI 972240 A0 FI972240 A0 FI 972240A0
Authority
FI
Finland
Prior art keywords
rapamycin
drugs
blocked
alkyl
oxide esters
Prior art date
Application number
FI972240A
Other languages
English (en)
Finnish (fi)
Other versions
FI972240A (sv
Inventor
Frances Christy Nelson
Guy Alan Schiehser
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of FI972240A publication Critical patent/FI972240A/sv
Publication of FI972240A0 publication Critical patent/FI972240A0/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI972240A 1994-11-28 1997-05-27 Förhindrade N-oxidestrar av rapamycin och deras användning som läkemedel FI972240A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/345,972 US5491231A (en) 1994-11-28 1994-11-28 Hindered N-oxide esters of rapamycin
PCT/US1995/015318 WO1996016967A1 (en) 1994-11-28 1995-11-22 Hindered n-oxide esters of rapamycin and their use as medicaments

Publications (2)

Publication Number Publication Date
FI972240A FI972240A (sv) 1997-05-27
FI972240A0 true FI972240A0 (sv) 1997-05-27

Family

ID=23357367

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972240A FI972240A0 (sv) 1994-11-28 1997-05-27 Förhindrade N-oxidestrar av rapamycin och deras användning som läkemedel

Country Status (19)

Country Link
US (5) US5491231A (sv)
EP (1) EP0794955B1 (sv)
JP (1) JPH10509977A (sv)
KR (1) KR100377278B1 (sv)
AT (1) ATE203539T1 (sv)
AU (1) AU712998B2 (sv)
BR (1) BR9509825A (sv)
CA (1) CA2205577A1 (sv)
DE (1) DE69521907T2 (sv)
DK (1) DK0794955T3 (sv)
ES (1) ES2158959T3 (sv)
FI (1) FI972240A0 (sv)
GR (1) GR3036712T3 (sv)
HK (1) HK1002281A1 (sv)
HU (1) HUT77139A (sv)
MX (1) MX9703893A (sv)
NZ (1) NZ297661A (sv)
PT (1) PT794955E (sv)
WO (1) WO1996016967A1 (sv)

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Also Published As

Publication number Publication date
EP0794955A1 (en) 1997-09-17
EP0794955B1 (en) 2001-07-25
DK0794955T3 (da) 2001-09-24
US5491231A (en) 1996-02-13
US5508285A (en) 1996-04-16
US5508290A (en) 1996-04-16
HK1002281A1 (en) 1998-08-14
FI972240A (sv) 1997-05-27
US5521194A (en) 1996-05-28
HUT77139A (hu) 1998-03-02
ATE203539T1 (de) 2001-08-15
DE69521907T2 (de) 2001-11-29
BR9509825A (pt) 1997-09-30
ES2158959T3 (es) 2001-09-16
AU4287796A (en) 1996-06-19
JPH10509977A (ja) 1998-09-29
DE69521907D1 (de) 2001-08-30
WO1996016967A1 (en) 1996-06-06
CA2205577A1 (en) 1996-06-06
MX9703893A (es) 1997-08-30
AU712998B2 (en) 1999-11-18
US5559122A (en) 1996-09-24
KR100377278B1 (ko) 2003-10-04
NZ297661A (en) 2000-01-28
PT794955E (pt) 2001-12-28
GR3036712T3 (en) 2001-12-31

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