FI97136B - Menetelmä terapeuttisesti käyttökelpoisten 4-metoksi-10-(1-hydroksietyyli)-11-okso-1-atsatrisyklo/7.2.0.03,8/-undek-2-eeni-2-karboksyylihappojen asyylioksialkyyliestereiden valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 4-metoksi-10-(1-hydroksietyyli)-11-okso-1-atsatrisyklo/7.2.0.03,8/-undek-2-eeni-2-karboksyylihappojen asyylioksialkyyliestereiden valmistamiseksi

Info

Publication number
FI97136B
FI97136B FI921717A FI921717A FI97136B FI 97136 B FI97136 B FI 97136B FI 921717 A FI921717 A FI 921717A FI 921717 A FI921717 A FI 921717A FI 97136 B FI97136 B FI 97136B
Authority
FI
Finland
Prior art keywords
azatricyclo
undec
ene
oxo
hydroxyethyl
Prior art date
Application number
FI921717A
Other languages
English (en)
Swedish (sv)
Other versions
FI921717A0 (fi
FI97136C (fi
FI921717A (fi
Inventor
Alcide Perboni
Tino Rossi
Giovanni Gaviraghi
Antonella Ursini
Giorgio Tarzia
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909018330A external-priority patent/GB9018330D0/en
Priority claimed from GB919104770A external-priority patent/GB9104770D0/en
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of FI921717A0 publication Critical patent/FI921717A0/fi
Publication of FI921717A publication Critical patent/FI921717A/fi
Application granted granted Critical
Publication of FI97136B publication Critical patent/FI97136B/fi
Publication of FI97136C publication Critical patent/FI97136C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI921717A 1990-08-21 1992-04-16 Menetelmä terapeuttisesti käyttökelpoisten 4-metoksi-10-(1-hydroksietyyli)-11-okso-1-atsatrisyklo/7.2.0.03,8/-undek-2-eeni-2-karboksyylihappojen asyylioksialkyyliestereiden valmistamiseksi FI97136C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9018330 1990-08-21
GB909018330A GB9018330D0 (en) 1990-08-21 1990-08-21 Heterocyclic compounds
GB9104770 1991-03-07
GB919104770A GB9104770D0 (en) 1991-03-07 1991-03-07 Heterocyclic compounds
PCT/EP1991/001589 WO1992003437A1 (en) 1990-08-21 1991-08-20 10(1-hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-ene-2-carboxylic acid esters and a process for preparing thereof
EP9101589 1991-08-20

Publications (4)

Publication Number Publication Date
FI921717A0 FI921717A0 (fi) 1992-04-16
FI921717A FI921717A (fi) 1992-04-16
FI97136B true FI97136B (fi) 1996-07-15
FI97136C FI97136C (fi) 1996-10-25

Family

ID=26297540

Family Applications (1)

Application Number Title Priority Date Filing Date
FI921717A FI97136C (fi) 1990-08-21 1992-04-16 Menetelmä terapeuttisesti käyttökelpoisten 4-metoksi-10-(1-hydroksietyyli)-11-okso-1-atsatrisyklo/7.2.0.03,8/-undek-2-eeni-2-karboksyylihappojen asyylioksialkyyliestereiden valmistamiseksi

Country Status (32)

Country Link
US (1) US5587374A (fi)
EP (1) EP0495953B1 (fi)
JP (2) JP3151215B2 (fi)
KR (1) KR0169147B1 (fi)
CN (1) CN1030917C (fi)
AP (1) AP238A (fi)
AT (1) ATE106887T1 (fi)
AU (1) AU647178B2 (fi)
CA (1) CA2067741C (fi)
CY (1) CY2037A (fi)
CZ (1) CZ280942B6 (fi)
DE (1) DE69102415T2 (fi)
DK (1) DK0495953T3 (fi)
ES (1) ES2054502T3 (fi)
FI (1) FI97136C (fi)
HK (1) HK19495A (fi)
HR (1) HRP940556B1 (fi)
HU (2) HUT61024A (fi)
IE (1) IE66122B1 (fi)
IL (1) IL99248A (fi)
MX (1) MX9100743A (fi)
MY (1) MY106997A (fi)
NO (1) NO300176B1 (fi)
NZ (1) NZ239474A (fi)
OA (1) OA09578A (fi)
PL (1) PL169425B1 (fi)
PT (1) PT98729B (fi)
SG (1) SG169494G (fi)
SI (1) SI9111427B (fi)
SK (1) SK278470B6 (fi)
WO (1) WO1992003437A1 (fi)
YU (1) YU48079B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
AP294A (en) * 1992-08-31 1993-12-28 Glaxo Spa "10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8) undec-2-ene-2-carboxylic acid derivatives".
GB9218781D0 (en) * 1992-09-04 1992-10-21 Glaxo Spa Heterocyclic derivatives
IN188720B (fi) * 1997-11-06 2002-11-02 Panacea Biotec Ltd
WO2003040146A1 (fr) 2001-11-05 2003-05-15 Sumitomo Pharmaceuticals Co., Ltd. Nouveaux composes carbapenem
CA2519794A1 (en) * 2003-04-08 2004-10-21 Sumitomo Pharmaceuticals Co., Ltd. Novel carbapenem compounds
JPWO2006025475A1 (ja) * 2004-09-03 2008-05-08 大日本住友製薬株式会社 新規なカルバペネム化合物
WO2006103999A1 (ja) * 2005-03-25 2006-10-05 Dainippon Sumitomo Pharma Co., Ltd. 新規なカルバペネム化合物
EP2085084A1 (en) 2008-01-29 2009-08-05 LEK Pharmaceuticals D.D. Use of inhibitor of beta-lactamases and its combination with beta-lactam antibiotics
EP2135871A1 (en) * 2008-06-18 2009-12-23 LEK Pharmaceuticals D.D. New trinem antibiotics and inhibitors of beta-lactamases
CN110869016B (zh) 2017-05-08 2023-09-12 葛兰素史密斯克莱知识产权发展有限公司 用于治疗分枝杆菌感染的山费培南或其盐或酯

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1433131A (en) * 1972-03-13 1976-04-22 Astra Laekemedel Ab Penicillins
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4374848A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-(1-Hydroxyethyl)cyclonocardicin
US4374849A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-Amidocyclonocardicins
CZ285778B6 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds
GB9104832D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
AU8421291A (en) 1992-03-17
CN1030917C (zh) 1996-02-07
WO1992003437A1 (en) 1992-03-05
IL99248A0 (en) 1992-07-15
HK19495A (en) 1995-02-17
US5587374A (en) 1996-12-24
NO921521D0 (no) 1992-04-15
MY106997A (en) 1995-08-30
JP2000351730A (ja) 2000-12-19
SI9111427B (sl) 2000-10-31
CA2067741A1 (en) 1992-02-22
HU211584A9 (en) 1995-12-28
YU142791A (sh) 1994-01-20
IE912944A1 (en) 1992-02-26
FI921717A0 (fi) 1992-04-16
DK0495953T3 (da) 1994-07-18
SG169494G (en) 1995-04-28
FI97136C (fi) 1996-10-25
IL99248A (en) 1996-01-31
CN1060094A (zh) 1992-04-08
KR0169147B1 (en) 1999-01-15
ATE106887T1 (de) 1994-06-15
JP3461786B2 (ja) 2003-10-27
ES2054502T3 (es) 1994-08-01
DE69102415D1 (de) 1994-07-14
NO300176B1 (no) 1997-04-21
SK121392A3 (en) 1997-06-04
NO921521L (no) 1992-06-22
PT98729A (pt) 1992-07-31
AP9100320A0 (en) 1991-10-31
FI921717A (fi) 1992-04-16
PL169425B1 (pl) 1996-07-31
JPH05502044A (ja) 1993-04-15
IE66122B1 (en) 1995-12-13
EP0495953B1 (en) 1994-06-08
PT98729B (pt) 1999-01-29
JP3151215B2 (ja) 2001-04-03
SK278470B6 (en) 1997-06-04
CY2037A (en) 1998-02-20
HRP940556B1 (en) 2000-06-30
SI9111427A (en) 1996-12-31
HUT61024A (en) 1992-11-30
EP0495953A1 (en) 1992-07-29
MX9100743A (es) 1992-04-01
AU647178B2 (en) 1994-03-17
NZ239474A (en) 1994-06-27
CZ121392A3 (en) 1993-04-14
HU9201303D0 (en) 1992-07-28
CA2067741C (en) 2002-01-01
HRP940556A2 (en) 1996-06-30
YU48079B (sh) 1997-01-08
CZ280942B6 (cs) 1996-05-15
KR920702361A (ko) 1992-09-03
AP238A (en) 1993-02-04
DE69102415T2 (de) 1994-10-13
OA09578A (en) 1993-01-31

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