FI103727B1 - Menetelmä terapeuttisesti käyttökelpoisten 2-amino-4-substioitu-fenyyli-4H-pyrano[3,2-h]kinoliini-3-karbonitriilien valmistamiseksi - Google Patents
Menetelmä terapeuttisesti käyttökelpoisten 2-amino-4-substioitu-fenyyli-4H-pyrano[3,2-h]kinoliini-3-karbonitriilien valmistamiseksiInfo
- Publication number
- FI103727B1 FI103727B1 FI935065A FI935065A FI103727B1 FI 103727 B1 FI103727 B1 FI 103727B1 FI 935065 A FI935065 A FI 935065A FI 935065 A FI935065 A FI 935065A FI 103727 B1 FI103727 B1 FI 103727B1
- Authority
- FI
- Finland
- Prior art keywords
- carbonitriles
- pyrano
- quinoline
- phenyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929224169A GB9224169D0 (en) | 1992-11-18 | 1992-11-18 | Pharmaceutical compounds |
GB9224169 | 1992-11-18 | ||
GB939302367A GB9302367D0 (en) | 1993-02-06 | 1993-02-06 | Pharmaceutical compounds |
GB9302367 | 1993-02-06 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI935065A0 FI935065A0 (fi) | 1993-11-16 |
FI935065A FI935065A (fi) | 1994-05-19 |
FI103727B1 true FI103727B1 (fi) | 1999-08-31 |
FI103727B FI103727B (fi) | 1999-08-31 |
Family
ID=26301995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI935065A FI103727B (fi) | 1992-11-18 | 1993-11-16 | Menetelmä terapeuttisesti käyttökelpoisten 2-amino-4-substioitu-fenyyli-4H-pyrano£3,2-h|kinoliini-3-karbonitriilien valmistamiseksi |
Country Status (16)
Country | Link |
---|---|
US (1) | US5434160A (fi) |
EP (2) | EP0599514A3 (fi) |
JP (1) | JPH06199862A (fi) |
KR (1) | KR940011465A (fi) |
CN (1) | CN1040982C (fi) |
AU (1) | AU668602B2 (fi) |
CA (1) | CA2103203A1 (fi) |
CO (1) | CO4130335A1 (fi) |
CZ (1) | CZ243493A3 (fi) |
FI (1) | FI103727B (fi) |
HU (1) | HU9303261D0 (fi) |
IL (1) | IL107627A (fi) |
NO (1) | NO304890B1 (fi) |
NZ (1) | NZ250195A (fi) |
PL (1) | PL301059A1 (fi) |
TW (1) | TW289755B (fi) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9306062D0 (en) * | 1993-03-24 | 1993-05-12 | Lilly Industries Ltd | Pharmaceutical compounds |
FR2795071B1 (fr) * | 1999-06-16 | 2001-07-27 | Adir | Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU781986B2 (en) | 1999-11-05 | 2005-06-23 | Cytovia, Inc. | Substituted 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US7053117B2 (en) | 2001-05-16 | 2006-05-30 | Cytovia, Inc. | Substituted 4H-chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US7015328B2 (en) | 2001-05-16 | 2006-03-21 | Cytovia, Inc. | Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US6858607B1 (en) | 2001-05-16 | 2005-02-22 | Cytovia, Inc. | 7,8-fused 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US7528164B2 (en) | 2002-05-16 | 2009-05-05 | Cytovia, Inc. | Substituted 4-aryl-4h-pyrrolo[2,3-h]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof |
EP1513515A2 (en) | 2002-05-16 | 2005-03-16 | Cytovia, Inc. | Substituted 4h-chromenes, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US20080194636A1 (en) | 2004-09-09 | 2008-08-14 | Howard Florey Institute Of Experimental Physiology And Medicine | Enzyme Inhibitors and Uses Thereof |
US7843312B2 (en) * | 2006-12-12 | 2010-11-30 | Honeywell International Inc. | Wireless control of security system with key-operated key fob |
WO2009065169A1 (en) | 2007-11-19 | 2009-05-28 | Howard Florey Institute | Insulin-regulated aminopeptidase (irap) inhibitors and uses thereof |
CN103328463B (zh) | 2010-11-12 | 2018-04-03 | 德国癌症研究中心 | 作为Wnt通路拮抗剂的色烯衍生物及其类似物 |
WO2023099589A1 (en) * | 2021-12-01 | 2023-06-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Irap inhibitors for use in the treatment of inflammatory diseases |
CN115028643B (zh) * | 2022-06-10 | 2024-03-22 | 中国药科大学 | 吡喃并喹啉衍生物及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4243674A (en) * | 1978-06-12 | 1981-01-06 | Pfizer Inc. | 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore |
JPS61502124A (ja) * | 1984-05-09 | 1986-09-25 | ジ オ−ストラリアン ナシヨナル ユニヴア−シテイ− | 免疫応答の調節方法 |
JP2631710B2 (ja) * | 1988-08-16 | 1997-07-16 | 日本ヘキスト・マリオン・ルセル株式会社 | ピラノ〔f〕キノリノン誘導体及び該化合物を有効成分とする医薬組成物 |
US4931221A (en) * | 1988-12-30 | 1990-06-05 | Ppg Industries, Inc. | Photochromic spiropyran compounds |
US5284868A (en) * | 1991-10-09 | 1994-02-08 | Eli Lilly And Company | Pharmaceutical compounds |
GB9306062D0 (en) * | 1993-03-24 | 1993-05-12 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1993
- 1993-11-11 EP EP19930308999 patent/EP0599514A3/en not_active Ceased
- 1993-11-11 EP EP99204310A patent/EP1004584A3/en not_active Withdrawn
- 1993-11-12 US US08/150,945 patent/US5434160A/en not_active Expired - Fee Related
- 1993-11-15 AU AU50671/93A patent/AU668602B2/en not_active Ceased
- 1993-11-15 CZ CZ932434A patent/CZ243493A3/cs unknown
- 1993-11-15 NZ NZ250195A patent/NZ250195A/en unknown
- 1993-11-15 PL PL93301059A patent/PL301059A1/xx unknown
- 1993-11-15 TW TW082109528A patent/TW289755B/zh active
- 1993-11-16 IL IL107627A patent/IL107627A/xx not_active IP Right Cessation
- 1993-11-16 KR KR1019930024262A patent/KR940011465A/ko not_active Application Discontinuation
- 1993-11-16 NO NO934145A patent/NO304890B1/no not_active IP Right Cessation
- 1993-11-16 CA CA002103203A patent/CA2103203A1/en not_active Abandoned
- 1993-11-16 FI FI935065A patent/FI103727B/fi active
- 1993-11-17 JP JP5287139A patent/JPH06199862A/ja active Pending
- 1993-11-17 CN CN93115028A patent/CN1040982C/zh not_active Expired - Fee Related
- 1993-11-17 HU HU9303261A patent/HU9303261D0/hu unknown
- 1993-11-17 CO CO93418738A patent/CO4130335A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN1040982C (zh) | 1998-12-02 |
FI935065A (fi) | 1994-05-19 |
CZ243493A3 (en) | 1994-06-15 |
CN1092072A (zh) | 1994-09-14 |
NZ250195A (en) | 1995-12-21 |
TW289755B (fi) | 1996-11-01 |
US5434160A (en) | 1995-07-18 |
NO934145D0 (no) | 1993-11-16 |
HU9303261D0 (en) | 1994-03-28 |
KR940011465A (ko) | 1994-06-21 |
EP0599514A2 (en) | 1994-06-01 |
FI103727B (fi) | 1999-08-31 |
EP1004584A2 (en) | 2000-05-31 |
CO4130335A1 (es) | 1995-02-13 |
NO934145L (no) | 1994-05-19 |
IL107627A (en) | 1997-04-15 |
EP0599514A3 (en) | 1994-07-06 |
CA2103203A1 (en) | 1994-05-19 |
AU668602B2 (en) | 1996-05-09 |
JPH06199862A (ja) | 1994-07-19 |
FI935065A0 (fi) | 1993-11-16 |
IL107627A0 (en) | 1994-02-27 |
AU5067193A (en) | 1994-06-02 |
NO304890B1 (no) | 1999-03-01 |
PL301059A1 (en) | 1994-05-30 |
EP1004584A3 (en) | 2000-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI890282A (fi) | Menetelmä terapeuttisesti käyttökelpoisten 23,24-didehydro-25-hydroksikalsiferolijohdannaisten valmistamiseksi | |
FI92934B (fi) | Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-deoksinojirimysiinijohdannaisten valmistamiseksi | |
FI945441A (fi) | Uusi menetelmä 7beta-substituoitu-4-atsa-5alfa-androstan-3-onien valmistamiseksi | |
FI103666B1 (fi) | Menetelmä bifenyylijohdannaisen valmistamiseksi | |
FI952585A (fi) | Menetelmä bentsopyraaniyhdisteiden valmistamiseksi | |
FI103727B1 (fi) | Menetelmä terapeuttisesti käyttökelpoisten 2-amino-4-substioitu-fenyyli-4H-pyrano[3,2-h]kinoliini-3-karbonitriilien valmistamiseksi | |
FI880467A (fi) | Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 3,4-dihydro-2H-bentsopyraanien valmistamiseksi | |
FI104075B1 (fi) | Menetelmä terapeuttisesti käyttökelpoisten 2-karboksitienyylikarbamoyylipyrrolidin-4-yylitiokarbapeneemi-3-karboksyylihappojohdannaisten valmistamiseksi | |
FI941776A (fi) | Menetelmä 1,2,4-tiadiatsolien valmistamiseksi | |
FI98461B (fi) | Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi | |
FI98459B (fi) | Menetelmä terapeuttisesti käyttökelpoisten 5-etano-2,3,4,5-1H-2-bentsatsepin-7-olikarbamaattijohdannaisten valmistamiseksi | |
FI903077A0 (fi) | Menetelmä valmistaa terapeuttisesti aktiivisia R(-)-3-kinuklidinolijohdannaisia | |
FI911701A (fi) | Menetelmä terapeuttisesti käyttökelpoisten 2-substituoitujen alkyyli-3-karboksikarbapeneemien valmistamiseksi | |
FI973644A (fi) | Uusi menetelmä 2,3-dihydrobentsofuranolijohdannaisten valmistamiseksi | |
AU3213593A (en) | Process for the preparation of 1,1,1,2-tetrafluoroethane | |
EP0557949A3 (en) | Process for the preparation of 2,4,5 trifluorobenzonitrile | |
FI942394A0 (fi) | Menetelmä steroidiperasyyliglykosidien valmistamiseksi | |
FI943833A (fi) | Menetelmä 2,3,5,6-tetraklooripyridiinin valmistamiseksi | |
NO179101C (no) | Fremgangsmåte for fremstilling av dibeskyttet 2,3-hydroksymetyl-cyklobutanol | |
FI102841B1 (fi) | Menetelmä mannitolin valmistamiseksi | |
FI940551A (fi) | Menetelmä fenyylibentsamidijohdannaisten valmistamiseksi | |
FI971964A0 (fi) | Menetelmä 1-halo-3-trialkyylisilasnyylibentseenijohdannaisten valmistamiseksi | |
ZA936874B (en) | Process for the preparation of 5,6-diacetoxyindole | |
FI943660A0 (fi) | Menetelmä 3-karbonyyliandrostadieeni-17-karboksamidien valmistamiseksi | |
FI951441A (fi) | Menetelmä 5-formyyliamino-pyrimidiinien valmistamiseksi |