FI103727B1 - Förfarande för framställning av terapeutiskt användbara 2-amino-4-substituerad-fenyl-4H-pyrano[3,2-h]kinolin-3-karbonitriler - Google Patents
Förfarande för framställning av terapeutiskt användbara 2-amino-4-substituerad-fenyl-4H-pyrano[3,2-h]kinolin-3-karbonitrilerInfo
- Publication number
- FI103727B1 FI103727B1 FI935065A FI935065A FI103727B1 FI 103727 B1 FI103727 B1 FI 103727B1 FI 935065 A FI935065 A FI 935065A FI 935065 A FI935065 A FI 935065A FI 103727 B1 FI103727 B1 FI 103727B1
- Authority
- FI
- Finland
- Prior art keywords
- carbonitriles
- pyrano
- quinoline
- phenyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929224169A GB9224169D0 (en) | 1992-11-18 | 1992-11-18 | Pharmaceutical compounds |
| GB9224169 | 1992-11-18 | ||
| GB9302367 | 1993-02-06 | ||
| GB939302367A GB9302367D0 (en) | 1993-02-06 | 1993-02-06 | Pharmaceutical compounds |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI935065A0 FI935065A0 (fi) | 1993-11-16 |
| FI935065A FI935065A (fi) | 1994-05-19 |
| FI103727B FI103727B (sv) | 1999-08-31 |
| FI103727B1 true FI103727B1 (sv) | 1999-08-31 |
Family
ID=26301995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI935065A FI103727B1 (sv) | 1992-11-18 | 1993-11-16 | Förfarande för framställning av terapeutiskt användbara 2-amino-4-substituerad-fenyl-4H-pyrano[3,2-h]kinolin-3-karbonitriler |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5434160A (sv) |
| EP (2) | EP1004584A3 (sv) |
| JP (1) | JPH06199862A (sv) |
| KR (1) | KR940011465A (sv) |
| CN (1) | CN1040982C (sv) |
| AU (1) | AU668602B2 (sv) |
| CA (1) | CA2103203A1 (sv) |
| CO (1) | CO4130335A1 (sv) |
| CZ (1) | CZ243493A3 (sv) |
| FI (1) | FI103727B1 (sv) |
| HU (1) | HU9303261D0 (sv) |
| IL (1) | IL107627A (sv) |
| NO (1) | NO304890B1 (sv) |
| NZ (1) | NZ250195A (sv) |
| PL (1) | PL301059A1 (sv) |
| TW (1) | TW289755B (sv) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9306062D0 (en) * | 1993-03-24 | 1993-05-12 | Lilly Industries Ltd | Pharmaceutical compounds |
| FR2795071B1 (fr) * | 1999-06-16 | 2001-07-27 | Adir | Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| AU781986B2 (en) | 1999-11-05 | 2005-06-23 | Cytovia, Inc. | Substituted 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| WO2002092076A1 (en) | 2001-05-16 | 2002-11-21 | Cytovia, Inc. | Substituted coumarins and quinolines as caspases activators |
| JP4593880B2 (ja) | 2001-05-16 | 2010-12-08 | サイトビア インコーポレイテッド | カスパーゼの活性化因子およびアポトーシスの誘導因子としての置換された４ｈ−クロメンおよび類似体、並びにその使用方法 |
| US6858607B1 (en) | 2001-05-16 | 2005-02-22 | Cytovia, Inc. | 7,8-fused 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| US7476741B2 (en) | 2002-05-16 | 2009-01-13 | Cytovia, Inc. | Substituted 4H-chromens, 2H-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| AU2003230411A1 (en) | 2002-05-16 | 2003-12-02 | Cytovia, Inc. | Substituted 4-aryl-4h-pyrrolo(2,3-h)chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| JP5031567B2 (ja) * | 2004-09-09 | 2012-09-19 | ハワード・フローレイ・インスティテュート・オブ・イクスペリメンタル・フィジオロジー・アンド・メディスン | 酵素阻害剤およびその使用 |
| US7843312B2 (en) * | 2006-12-12 | 2010-11-30 | Honeywell International Inc. | Wireless control of security system with key-operated key fob |
| NZ585338A (en) | 2007-11-19 | 2012-08-31 | Howard Florey Inst | Insulin-regulated aminopeptidase (irap) inhibitors and uses thereof |
| CA2817331C (en) | 2010-11-12 | 2019-09-10 | Deutsches Krebsforschungszentrum (Dkfz) | Chromene derivatives and their analoga as wnt pathway antagonists |
| WO2023099589A1 (en) * | 2021-12-01 | 2023-06-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Irap inhibitors for use in the treatment of inflammatory diseases |
| CN115028643B (zh) * | 2022-06-10 | 2024-03-22 | 中国药科大学 | 吡喃并喹啉衍生物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4243674A (en) * | 1978-06-12 | 1981-01-06 | Pfizer Inc. | 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore |
| JPS61502124A (ja) * | 1984-05-09 | 1986-09-25 | ジ オ−ストラリアン ナシヨナル ユニヴア−シテイ− | 免疫応答の調節方法 |
| JP2631710B2 (ja) * | 1988-08-16 | 1997-07-16 | 日本ヘキスト・マリオン・ルセル株式会社 | ピラノ〔ｆ〕キノリノン誘導体及び該化合物を有効成分とする医薬組成物 |
| US4931221A (en) * | 1988-12-30 | 1990-06-05 | Ppg Industries, Inc. | Photochromic spiropyran compounds |
| US5284868A (en) * | 1991-10-09 | 1994-02-08 | Eli Lilly And Company | Pharmaceutical compounds |
| GB9306062D0 (en) * | 1993-03-24 | 1993-05-12 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1993
- 1993-11-11 EP EP99204310A patent/EP1004584A3/en not_active Withdrawn
- 1993-11-11 EP EP19930308999 patent/EP0599514A3/en not_active Ceased
- 1993-11-12 US US08/150,945 patent/US5434160A/en not_active Expired - Fee Related
- 1993-11-15 PL PL93301059A patent/PL301059A1/xx unknown
- 1993-11-15 TW TW082109528A patent/TW289755B/zh active
- 1993-11-15 NZ NZ250195A patent/NZ250195A/en unknown
- 1993-11-15 AU AU50671/93A patent/AU668602B2/en not_active Ceased
- 1993-11-15 CZ CZ932434A patent/CZ243493A3/cs unknown
- 1993-11-16 IL IL107627A patent/IL107627A/xx not_active IP Right Cessation
- 1993-11-16 NO NO934145A patent/NO304890B1/no not_active IP Right Cessation
- 1993-11-16 KR KR1019930024262A patent/KR940011465A/ko not_active Application Discontinuation
- 1993-11-16 CA CA002103203A patent/CA2103203A1/en not_active Abandoned
- 1993-11-16 FI FI935065A patent/FI103727B1/sv active
- 1993-11-17 JP JP5287139A patent/JPH06199862A/ja active Pending
- 1993-11-17 CN CN93115028A patent/CN1040982C/zh not_active Expired - Fee Related
- 1993-11-17 CO CO93418738A patent/CO4130335A1/es unknown
- 1993-11-17 HU HU9303261A patent/HU9303261D0/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0599514A3 (en) | 1994-07-06 |
| PL301059A1 (en) | 1994-05-30 |
| EP0599514A2 (en) | 1994-06-01 |
| CO4130335A1 (es) | 1995-02-13 |
| US5434160A (en) | 1995-07-18 |
| FI103727B (sv) | 1999-08-31 |
| NO934145L (no) | 1994-05-19 |
| JPH06199862A (ja) | 1994-07-19 |
| CN1092072A (zh) | 1994-09-14 |
| KR940011465A (ko) | 1994-06-21 |
| FI935065A (fi) | 1994-05-19 |
| CA2103203A1 (en) | 1994-05-19 |
| IL107627A (en) | 1997-04-15 |
| CZ243493A3 (en) | 1994-06-15 |
| NO304890B1 (no) | 1999-03-01 |
| AU5067193A (en) | 1994-06-02 |
| NZ250195A (en) | 1995-12-21 |
| NO934145D0 (no) | 1993-11-16 |
| EP1004584A2 (en) | 2000-05-31 |
| HU9303261D0 (en) | 1994-03-28 |
| TW289755B (sv) | 1996-11-01 |
| FI935065A0 (fi) | 1993-11-16 |
| IL107627A0 (en) | 1994-02-27 |
| EP1004584A3 (en) | 2000-07-05 |
| CN1040982C (zh) | 1998-12-02 |
| AU668602B2 (en) | 1996-05-09 |
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