IL107627A - Pharmaceutical compositions containing 3-substituted-2-amino-4- (hetero) arylpyrano (iso) quinoline derivatives, some new such derivatives and their preparation - Google Patents

Pharmaceutical compositions containing 3-substituted-2-amino-4- (hetero) arylpyrano (iso) quinoline derivatives, some new such derivatives and their preparation

Info

Publication number
IL107627A
IL107627A IL107627A IL10762793A IL107627A IL 107627 A IL107627 A IL 107627A IL 107627 A IL107627 A IL 107627A IL 10762793 A IL10762793 A IL 10762793A IL 107627 A IL107627 A IL 107627A
Authority
IL
Israel
Prior art keywords
phenyl
alkyl
optionally substituted
substituted
derivatives
Prior art date
Application number
IL107627A
Other languages
English (en)
Other versions
IL107627A0 (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929224169A external-priority patent/GB9224169D0/en
Priority claimed from GB939302367A external-priority patent/GB9302367D0/en
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of IL107627A0 publication Critical patent/IL107627A0/xx
Publication of IL107627A publication Critical patent/IL107627A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL107627A 1992-11-18 1993-11-16 Pharmaceutical compositions containing 3-substituted-2-amino-4- (hetero) arylpyrano (iso) quinoline derivatives, some new such derivatives and their preparation IL107627A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929224169A GB9224169D0 (en) 1992-11-18 1992-11-18 Pharmaceutical compounds
GB939302367A GB9302367D0 (en) 1993-02-06 1993-02-06 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
IL107627A0 IL107627A0 (en) 1994-02-27
IL107627A true IL107627A (en) 1997-04-15

Family

ID=26301995

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107627A IL107627A (en) 1992-11-18 1993-11-16 Pharmaceutical compositions containing 3-substituted-2-amino-4- (hetero) arylpyrano (iso) quinoline derivatives, some new such derivatives and their preparation

Country Status (16)

Country Link
US (1) US5434160A (fi)
EP (2) EP1004584A3 (fi)
JP (1) JPH06199862A (fi)
KR (1) KR940011465A (fi)
CN (1) CN1040982C (fi)
AU (1) AU668602B2 (fi)
CA (1) CA2103203A1 (fi)
CO (1) CO4130335A1 (fi)
CZ (1) CZ243493A3 (fi)
FI (1) FI103727B (fi)
HU (1) HU9303261D0 (fi)
IL (1) IL107627A (fi)
NO (1) NO304890B1 (fi)
NZ (1) NZ250195A (fi)
PL (1) PL301059A1 (fi)
TW (1) TW289755B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9306062D0 (en) * 1993-03-24 1993-05-12 Lilly Industries Ltd Pharmaceutical compounds
FR2795071B1 (fr) * 1999-06-16 2001-07-27 Adir Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PT1230232E (pt) 1999-11-05 2004-07-30 Cytovia Inc 4h-cromeno substituido e seus analogos como activadores de caspases e indutores de apoptose e sua utilizacao
EP1392283A4 (en) 2001-05-16 2004-10-20 Cytovia Inc COUMARINS AND SUBSTITUTED QUINOLINES USED AS CASPASE ACTIVATORS
EP1392683B1 (en) 2001-05-16 2009-12-02 Cytovia, Inc. Substituted 4h-chromenes and analogs as activators of caspases and inducers of apoptosis and their use as anticancer agents
US6858607B1 (en) 2001-05-16 2005-02-22 Cytovia, Inc. 7,8-fused 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof
EP1509515A4 (en) * 2002-05-16 2006-07-05 Cytovia Inc SUBSTITUTED 4-ARYL-4H-PYRROLO 2,3-H | CHROMENES AND ANALOGUES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THEIR USE
AU2003241482A1 (en) 2002-05-16 2003-12-02 Cytovia, Inc. Substituted 4h-chromenes, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2006026832A1 (en) * 2004-09-09 2006-03-16 Howard Florey Institute Of Experimental Physiology And Medicine Enzyme inhibitors and uses thereof
US7843312B2 (en) * 2006-12-12 2010-11-30 Honeywell International Inc. Wireless control of security system with key-operated key fob
US8263775B2 (en) 2007-11-19 2012-09-11 Howard Florey Institute Insulin-regulated aminopeptidase (IRAP) inhibitors and uses thereof
CN107235954A (zh) 2010-11-12 2017-10-10 德国癌症研究中心 作为Wnt通路拮抗剂的色烯衍生物及其类似物
EP4440570A1 (en) * 2021-12-01 2024-10-09 Institut National de la Santé et de la Recherche Médicale (INSERM) Irap inhibitors for use in the treatment of inflammatory diseases
CN115028643B (zh) * 2022-06-10 2024-03-22 中国药科大学 吡喃并喹啉衍生物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243674A (en) * 1978-06-12 1981-01-06 Pfizer Inc. 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore
EP0181351A4 (en) * 1984-05-09 1989-06-21 Univ Australian METHOD FOR MODULATING IMMUNE REACTION.
JP2631710B2 (ja) * 1988-08-16 1997-07-16 日本ヘキスト・マリオン・ルセル株式会社 ピラノ〔f〕キノリノン誘導体及び該化合物を有効成分とする医薬組成物
US4931221A (en) * 1988-12-30 1990-06-05 Ppg Industries, Inc. Photochromic spiropyran compounds
US5284868A (en) * 1991-10-09 1994-02-08 Eli Lilly And Company Pharmaceutical compounds
GB9306062D0 (en) * 1993-03-24 1993-05-12 Lilly Industries Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
EP1004584A3 (en) 2000-07-05
CN1040982C (zh) 1998-12-02
PL301059A1 (en) 1994-05-30
FI935065A0 (fi) 1993-11-16
IL107627A0 (en) 1994-02-27
EP0599514A2 (en) 1994-06-01
FI103727B1 (fi) 1999-08-31
NO934145D0 (no) 1993-11-16
AU5067193A (en) 1994-06-02
CZ243493A3 (en) 1994-06-15
NO934145L (no) 1994-05-19
NO304890B1 (no) 1999-03-01
EP1004584A2 (en) 2000-05-31
FI103727B (fi) 1999-08-31
EP0599514A3 (en) 1994-07-06
HU9303261D0 (en) 1994-03-28
TW289755B (fi) 1996-11-01
KR940011465A (ko) 1994-06-21
NZ250195A (en) 1995-12-21
FI935065A (fi) 1994-05-19
AU668602B2 (en) 1996-05-09
CO4130335A1 (es) 1995-02-13
US5434160A (en) 1995-07-18
CA2103203A1 (en) 1994-05-19
JPH06199862A (ja) 1994-07-19
CN1092072A (zh) 1994-09-14

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
HC Change of name of proprietor(s)
KB Patent renewed
RH1 Patent not in force