ES8608467A1 - Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol - Google Patents

Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol

Info

Publication number
ES8608467A1
ES8608467A1 ES543783A ES543783A ES8608467A1 ES 8608467 A1 ES8608467 A1 ES 8608467A1 ES 543783 A ES543783 A ES 543783A ES 543783 A ES543783 A ES 543783A ES 8608467 A1 ES8608467 A1 ES 8608467A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
alkoxy
trihalomethyl
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543783A
Other languages
English (en)
Other versions
ES543783A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8608467A1 publication Critical patent/ES8608467A1/es
Publication of ES543783A0 publication Critical patent/ES543783A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Digital Magnetic Recording (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Breakers (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE UN DERIVADO 1,1-DIFENILPROPAN-1-OL DE FORMULA (I) EN LA QUE R1 Y R2 PUEDEN SER HIDROGENO, HALOGENO, TRIHALOMETILO Y ALQUILO O ALCOXILO DE 1 A 4 ATOMOS DE C; R3 LOS MISMOS SUSTITUYENTES QUE R1 Y R2 CON LA EXCEPCION DEL HIDROGENO, R4 FENILO DIVERSAMENTE SUSTITUIDO Y N ES 1, 2, 3, 4 O 5. CONSISTE EN LA REDUCCION DE UN COMPUESTO DE FORMULA (II) EN EL QUE R1, R2 Y R3 Y N SON IGUALES A LOS DEFINIDOS ANTERIORMENTE Y Z ES VINILO O ETINILO, POR HIDROGENACION CATALITICA CON DIVERSOS CATALIZADORES DE HIDROGENACION, A PRESION ATMOSFERICA O SUPERIOR Y TEMPERATURA ENTRE 20JC Y LA DE EBULLICION. DE APLICACION COMO INDUCTORES DE ENZIMAS MONOOXIGENASAS DEL HIGADO PARA TRATAMIENTO DE ICTERICIA ENZIMOPATICA, ENFERMEDAD DE GILBERT, HIPERBILIRRUBINEMIAS NEONATALES, SINDROME DE CUSHING, ETC.
ES543783A 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol Expired ES8608467A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU824181A HU190053B (en) 1982-12-28 1982-12-28 Process for the production of new 1,1-diphenyl-propanol-derivatives, as well as of therapeutic preparations containing them

Publications (2)

Publication Number Publication Date
ES8608467A1 true ES8608467A1 (es) 1986-07-16
ES543783A0 ES543783A0 (es) 1986-07-16

Family

ID=10967229

Family Applications (5)

Application Number Title Priority Date Filing Date
ES528451A Expired ES8600188A1 (es) 1982-12-28 1983-12-27 Procedimiento de preparacion de un derivado 1,1-difenilpropan-1-ol
ES543783A Expired ES8608467A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
ES543784A Expired ES8604086A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
ES543781A Expired ES8604084A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
ES543782A Expired ES8604085A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES528451A Expired ES8600188A1 (es) 1982-12-28 1983-12-27 Procedimiento de preparacion de un derivado 1,1-difenilpropan-1-ol

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES543784A Expired ES8604086A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
ES543781A Expired ES8604084A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
ES543782A Expired ES8604085A1 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol

Country Status (14)

Country Link
US (1) US4605785A (es)
EP (1) EP0116787B1 (es)
JP (1) JPS59130828A (es)
AT (1) ATE25968T1 (es)
AU (1) AU562377B2 (es)
CA (1) CA1250857A (es)
DE (1) DE3370322D1 (es)
DK (1) DK159650C (es)
ES (5) ES8600188A1 (es)
FI (1) FI77841C (es)
GR (1) GR79154B (es)
HU (1) HU190053B (es)
IL (1) IL70549A (es)
ZA (1) ZA839609B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191966B (en) * 1984-10-25 1987-04-28 Richter Gedeon Vegyeszet Fodder additive and process for producing same
US7858825B2 (en) * 2007-02-15 2010-12-28 Colorado State University Research Foundation Acid and base stable diphenylmethanol derivatives and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094908A (en) * 1973-08-15 1978-06-13 Richter Gedeon Vegyeszeti Gyar Rt. Alpha-substituted benzhydrol derivatives
HU168432B (es) * 1973-08-15 1976-04-28
JPS5195049A (en) * 1975-02-12 1976-08-20 * **********so*****no***tsu*****************************************ni*no
EP0002408A1 (fr) * 1977-11-26 1979-06-13 SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: Nouveaux composés phénoxy-alcanols substitués, leur procédé de préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
HUT34943A (en) 1985-05-28
IL70549A (en) 1986-09-30
ZA839609B (en) 1984-08-29
DK602383D0 (da) 1983-12-27
ES543783A0 (es) 1986-07-16
EP0116787B1 (en) 1987-03-18
AU562377B2 (en) 1987-06-11
ES543784A0 (es) 1986-01-16
AU2290483A (en) 1984-07-05
DK602383A (da) 1984-06-29
ES528451A0 (es) 1985-10-01
ES543782A0 (es) 1986-01-16
DE3370322D1 (en) 1987-04-23
EP0116787A1 (en) 1984-08-29
GR79154B (es) 1984-10-02
ES8600188A1 (es) 1985-10-01
ATE25968T1 (de) 1987-04-15
ES543781A0 (es) 1986-01-16
DK159650B (da) 1990-11-12
FI834789A (fi) 1984-06-29
JPH0237902B2 (es) 1990-08-28
JPS59130828A (ja) 1984-07-27
FI77841C (fi) 1989-05-10
ES8604086A1 (es) 1986-01-16
US4605785A (en) 1986-08-12
HU190053B (en) 1986-08-28
IL70549A0 (en) 1984-03-30
FI834789A0 (fi) 1983-12-27
DK159650C (da) 1991-04-08
FI77841B (fi) 1989-01-31
ES8604085A1 (es) 1986-01-16
CA1250857A (en) 1989-03-07
ES8604084A1 (es) 1986-01-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519