ES8604085A1 - Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol - Google Patents
Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-olInfo
- Publication number
- ES8604085A1 ES8604085A1 ES543782A ES543782A ES8604085A1 ES 8604085 A1 ES8604085 A1 ES 8604085A1 ES 543782 A ES543782 A ES 543782A ES 543782 A ES543782 A ES 543782A ES 8604085 A1 ES8604085 A1 ES 8604085A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- alkoxy
- trihalomethyl
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Breakers (AREA)
- Luminescent Compositions (AREA)
- Digital Magnetic Recording (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 1,1-DIFENILPROPAN-1-OL, DE FORMULA (I), EN LA QUE R1, R2, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 1-5. COMPRENDE LA REACCION DE UNA PROPIOFENONA DE FORMULA (II), CON UN COMPUESTO REACTIVO DE GRIGNARD DE FORMULA (III), EN LAS QUE X ES UN ATOMO DE HALOGENO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN PROPORCION EQUIMOLECULAR, EN UN DISOLVENTE ORGANICO, INERTE, ANHIDRO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ICTERICIA ENZIMOPATICA, LA ENFERMEDAD DE GILBERT, EL SINDROME DE CUSHING Y OTRAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU824181A HU190053B (en) | 1982-12-28 | 1982-12-28 | Process for the production of new 1,1-diphenyl-propanol-derivatives, as well as of therapeutic preparations containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES543782A0 ES543782A0 (es) | 1986-01-16 |
| ES8604085A1 true ES8604085A1 (es) | 1986-01-16 |
Family
ID=10967229
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528451A Expired ES8600188A1 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de un derivado 1,1-difenilpropan-1-ol |
| ES543781A Expired ES8604084A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543783A Expired ES8608467A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543784A Expired ES8604086A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543782A Expired ES8604085A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528451A Expired ES8600188A1 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de un derivado 1,1-difenilpropan-1-ol |
| ES543781A Expired ES8604084A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543783A Expired ES8608467A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543784A Expired ES8604086A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4605785A (es) |
| EP (1) | EP0116787B1 (es) |
| JP (1) | JPS59130828A (es) |
| AT (1) | ATE25968T1 (es) |
| AU (1) | AU562377B2 (es) |
| CA (1) | CA1250857A (es) |
| DE (1) | DE3370322D1 (es) |
| DK (1) | DK159650C (es) |
| ES (5) | ES8600188A1 (es) |
| FI (1) | FI77841C (es) |
| GR (1) | GR79154B (es) |
| HU (1) | HU190053B (es) |
| IL (1) | IL70549A (es) |
| ZA (1) | ZA839609B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU191966B (en) * | 1984-10-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Fodder additive and process for producing same |
| US7858825B2 (en) * | 2007-02-15 | 2010-12-28 | Colorado State University Research Foundation | Acid and base stable diphenylmethanol derivatives and methods of use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4094908A (en) * | 1973-08-15 | 1978-06-13 | Richter Gedeon Vegyeszeti Gyar Rt. | Alpha-substituted benzhydrol derivatives |
| HU168432B (es) * | 1973-08-15 | 1976-04-28 | ||
| JPS5195049A (en) * | 1975-02-12 | 1976-08-20 | * **********so*****no***tsu*****************************************ni*no | |
| EP0002408A1 (fr) * | 1977-11-26 | 1979-06-13 | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: | Nouveaux composés phénoxy-alcanols substitués, leur procédé de préparation et leur application en thérapeutique |
-
1982
- 1982-12-28 HU HU824181A patent/HU190053B/hu not_active IP Right Cessation
-
1983
- 1983-12-23 EP EP83307965A patent/EP0116787B1/en not_active Expired
- 1983-12-23 DE DE8383307965T patent/DE3370322D1/de not_active Expired
- 1983-12-23 AT AT83307965T patent/ATE25968T1/de not_active IP Right Cessation
- 1983-12-23 CA CA000444254A patent/CA1250857A/en not_active Expired
- 1983-12-23 AU AU22904/83A patent/AU562377B2/en not_active Ceased
- 1983-12-27 IL IL70549A patent/IL70549A/xx unknown
- 1983-12-27 ES ES528451A patent/ES8600188A1/es not_active Expired
- 1983-12-27 US US06/565,838 patent/US4605785A/en not_active Expired - Fee Related
- 1983-12-27 FI FI834789A patent/FI77841C/fi not_active IP Right Cessation
- 1983-12-27 JP JP58244941A patent/JPS59130828A/ja active Granted
- 1983-12-27 ZA ZA839609A patent/ZA839609B/xx unknown
- 1983-12-27 DK DK602383A patent/DK159650C/da not_active IP Right Cessation
- 1983-12-28 GR GR73368A patent/GR79154B/el unknown
-
1985
- 1985-06-01 ES ES543781A patent/ES8604084A1/es not_active Expired
- 1985-06-01 ES ES543783A patent/ES8608467A1/es not_active Expired
- 1985-06-01 ES ES543784A patent/ES8604086A1/es not_active Expired
- 1985-06-01 ES ES543782A patent/ES8604085A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ATE25968T1 (de) | 1987-04-15 |
| ES543783A0 (es) | 1986-07-16 |
| ES8604086A1 (es) | 1986-01-16 |
| ES8608467A1 (es) | 1986-07-16 |
| DK602383A (da) | 1984-06-29 |
| EP0116787B1 (en) | 1987-03-18 |
| FI834789A0 (fi) | 1983-12-27 |
| ES543782A0 (es) | 1986-01-16 |
| CA1250857A (en) | 1989-03-07 |
| ES543781A0 (es) | 1986-01-16 |
| IL70549A0 (en) | 1984-03-30 |
| HU190053B (en) | 1986-08-28 |
| DK159650C (da) | 1991-04-08 |
| ES543784A0 (es) | 1986-01-16 |
| DE3370322D1 (en) | 1987-04-23 |
| IL70549A (en) | 1986-09-30 |
| JPS59130828A (ja) | 1984-07-27 |
| ZA839609B (en) | 1984-08-29 |
| GR79154B (es) | 1984-10-02 |
| US4605785A (en) | 1986-08-12 |
| FI834789A (fi) | 1984-06-29 |
| FI77841B (fi) | 1989-01-31 |
| AU2290483A (en) | 1984-07-05 |
| ES8604084A1 (es) | 1986-01-16 |
| HUT34943A (en) | 1985-05-28 |
| AU562377B2 (en) | 1987-06-11 |
| FI77841C (fi) | 1989-05-10 |
| ES528451A0 (es) | 1985-10-01 |
| JPH0237902B2 (es) | 1990-08-28 |
| ES8600188A1 (es) | 1985-10-01 |
| DK159650B (da) | 1990-11-12 |
| DK602383D0 (da) | 1983-12-27 |
| EP0116787A1 (en) | 1984-08-29 |
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| Publication | Publication Date | Title |
|---|---|---|
| AU2291583A (en) | Dialkylaminoalkyoxybenzylalcohol derivatives | |
| ES8600244A1 (es) | Procedimiento de preparacion de nuevos derivados piridinicos y de sus sales de adicion acidas y cuaternarias | |
| ES8604086A1 (es) | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol | |
| DE3372757D1 (en) | Piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |