ES8604084A1 - Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol - Google Patents
Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-olInfo
- Publication number
- ES8604084A1 ES8604084A1 ES543781A ES543781A ES8604084A1 ES 8604084 A1 ES8604084 A1 ES 8604084A1 ES 543781 A ES543781 A ES 543781A ES 543781 A ES543781 A ES 543781A ES 8604084 A1 ES8604084 A1 ES 8604084A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- alkoxy
- trihalomethyl
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Digital Magnetic Recording (AREA)
- Luminescent Compositions (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Breakers (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 1,1-DIFENILPROPAN-1-OL, DE FORMULA (I), EN LA QUE R1, R2, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 1-5. CONSISTE EN LA REACCION DE CONDENSACION DE UNA BENZOFENONA DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON UN COMPUESTO ORGANOMETALICO QUE CONTENGA UN GRUPO ETILO, TAL COMO UN HALURO ETIL MAGNESICO O LITIO ETILICO. LA REACCION SE LLEVA A CABO EN PROPORCIONES EQUIVALENTES, EN UN DISOLVENTE ORGANICO, INERTE, ANHIDRO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ICTERICIA ENZIMOPATICA, LA ENFERMEDAD DE GILBERT, EL SINDROME DE CUSHING Y OTRAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU824181A HU190053B (en) | 1982-12-28 | 1982-12-28 | Process for the production of new 1,1-diphenyl-propanol-derivatives, as well as of therapeutic preparations containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES543781A0 ES543781A0 (es) | 1986-01-16 |
| ES8604084A1 true ES8604084A1 (es) | 1986-01-16 |
Family
ID=10967229
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528451A Granted ES528451A0 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de un derivado 1,1-difenilpropan-1-ol |
| ES543783A Expired ES8608467A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543782A Expired ES8604085A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543781A Expired ES8604084A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543784A Expired ES8604086A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528451A Granted ES528451A0 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de un derivado 1,1-difenilpropan-1-ol |
| ES543783A Expired ES8608467A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
| ES543782A Expired ES8604085A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES543784A Expired ES8604086A1 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4605785A (es) |
| EP (1) | EP0116787B1 (es) |
| JP (1) | JPS59130828A (es) |
| AT (1) | ATE25968T1 (es) |
| AU (1) | AU562377B2 (es) |
| CA (1) | CA1250857A (es) |
| DE (1) | DE3370322D1 (es) |
| DK (1) | DK159650C (es) |
| ES (5) | ES528451A0 (es) |
| FI (1) | FI77841C (es) |
| GR (1) | GR79154B (es) |
| HU (1) | HU190053B (es) |
| IL (1) | IL70549A (es) |
| ZA (1) | ZA839609B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU191966B (en) * | 1984-10-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Fodder additive and process for producing same |
| US7858825B2 (en) * | 2007-02-15 | 2010-12-28 | Colorado State University Research Foundation | Acid and base stable diphenylmethanol derivatives and methods of use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4094908A (en) * | 1973-08-15 | 1978-06-13 | Richter Gedeon Vegyeszeti Gyar Rt. | Alpha-substituted benzhydrol derivatives |
| HU168432B (es) * | 1973-08-15 | 1976-04-28 | ||
| JPS5195049A (en) * | 1975-02-12 | 1976-08-20 | * **********so*****no***tsu*****************************************ni*no | |
| EP0002408A1 (fr) * | 1977-11-26 | 1979-06-13 | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: | Nouveaux composés phénoxy-alcanols substitués, leur procédé de préparation et leur application en thérapeutique |
-
1982
- 1982-12-28 HU HU824181A patent/HU190053B/hu not_active IP Right Cessation
-
1983
- 1983-12-23 DE DE8383307965T patent/DE3370322D1/de not_active Expired
- 1983-12-23 CA CA000444254A patent/CA1250857A/en not_active Expired
- 1983-12-23 EP EP83307965A patent/EP0116787B1/en not_active Expired
- 1983-12-23 AT AT83307965T patent/ATE25968T1/de not_active IP Right Cessation
- 1983-12-23 AU AU22904/83A patent/AU562377B2/en not_active Ceased
- 1983-12-27 FI FI834789A patent/FI77841C/fi not_active IP Right Cessation
- 1983-12-27 JP JP58244941A patent/JPS59130828A/ja active Granted
- 1983-12-27 ZA ZA839609A patent/ZA839609B/xx unknown
- 1983-12-27 ES ES528451A patent/ES528451A0/es active Granted
- 1983-12-27 DK DK602383A patent/DK159650C/da not_active IP Right Cessation
- 1983-12-27 IL IL70549A patent/IL70549A/xx unknown
- 1983-12-27 US US06/565,838 patent/US4605785A/en not_active Expired - Fee Related
- 1983-12-28 GR GR73368A patent/GR79154B/el unknown
-
1985
- 1985-06-01 ES ES543783A patent/ES8608467A1/es not_active Expired
- 1985-06-01 ES ES543782A patent/ES8604085A1/es not_active Expired
- 1985-06-01 ES ES543781A patent/ES8604084A1/es not_active Expired
- 1985-06-01 ES ES543784A patent/ES8604086A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0116787A1 (en) | 1984-08-29 |
| ES543782A0 (es) | 1986-01-16 |
| ES8604085A1 (es) | 1986-01-16 |
| DK602383D0 (da) | 1983-12-27 |
| IL70549A (en) | 1986-09-30 |
| AU562377B2 (en) | 1987-06-11 |
| AU2290483A (en) | 1984-07-05 |
| ES8600188A1 (es) | 1985-10-01 |
| FI77841B (fi) | 1989-01-31 |
| DK159650C (da) | 1991-04-08 |
| ES8604086A1 (es) | 1986-01-16 |
| ES528451A0 (es) | 1985-10-01 |
| ATE25968T1 (de) | 1987-04-15 |
| FI834789A0 (fi) | 1983-12-27 |
| ZA839609B (en) | 1984-08-29 |
| HU190053B (en) | 1986-08-28 |
| GR79154B (es) | 1984-10-02 |
| ES8608467A1 (es) | 1986-07-16 |
| EP0116787B1 (en) | 1987-03-18 |
| DK159650B (da) | 1990-11-12 |
| US4605785A (en) | 1986-08-12 |
| DK602383A (da) | 1984-06-29 |
| JPH0237902B2 (es) | 1990-08-28 |
| ES543781A0 (es) | 1986-01-16 |
| CA1250857A (en) | 1989-03-07 |
| ES543783A0 (es) | 1986-07-16 |
| FI834789A (fi) | 1984-06-29 |
| HUT34943A (en) | 1985-05-28 |
| IL70549A0 (en) | 1984-03-30 |
| ES543784A0 (es) | 1986-01-16 |
| FI77841C (fi) | 1989-05-10 |
| DE3370322D1 (en) | 1987-04-23 |
| JPS59130828A (ja) | 1984-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |