FI964218A - Yhdisteitä, joilla on verenpainetta alentavia, sydäntä suojaavia, verettömyyttä vastustavia ja rasvaa hajottavia ominaisuuksia - Google Patents

Yhdisteitä, joilla on verenpainetta alentavia, sydäntä suojaavia, verettömyyttä vastustavia ja rasvaa hajottavia ominaisuuksia Download PDF

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Publication number
FI964218A
FI964218A FI964218A FI964218A FI964218A FI 964218 A FI964218 A FI 964218A FI 964218 A FI964218 A FI 964218A FI 964218 A FI964218 A FI 964218A FI 964218 A FI964218 A FI 964218A
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Finland
Prior art keywords
antihaemorrhagic
cardioprotective
antihypertensive
lipid
compounds
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Application number
FI964218A
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English (en)
Swedish (sv)
Other versions
FI964218A0 (fi
Inventor
Alfred P Spada
Cynthia A Fink
Michael R Myers
Original Assignee
Rhone Poulenc Rorer Pharma
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Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of FI964218A0 publication Critical patent/FI964218A0/fi
Publication of FI964218A publication Critical patent/FI964218A/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI964218A 1994-04-19 1996-10-18 Yhdisteitä, joilla on verenpainetta alentavia, sydäntä suojaavia, verettömyyttä vastustavia ja rasvaa hajottavia ominaisuuksia FI964218A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22988294A 1994-04-19 1994-04-19
US08/316,761 US5561134A (en) 1990-09-25 1994-10-03 Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
PCT/US1995/004800 WO1995028160A1 (en) 1994-04-19 1995-04-19 Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties

Publications (2)

Publication Number Publication Date
FI964218A0 FI964218A0 (fi) 1996-10-18
FI964218A true FI964218A (fi) 1996-12-17

Family

ID=26923699

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964218A FI964218A (fi) 1994-04-19 1996-10-18 Yhdisteitä, joilla on verenpainetta alentavia, sydäntä suojaavia, verettömyyttä vastustavia ja rasvaa hajottavia ominaisuuksia

Country Status (29)

Country Link
US (2) US5561134A (fi)
EP (2) EP1006115A3 (fi)
JP (1) JPH09512020A (fi)
KR (1) KR970702045A (fi)
CN (1) CN1086704C (fi)
AP (1) AP699A (fi)
AT (1) ATE260106T1 (fi)
AU (1) AU684635B2 (fi)
BG (1) BG63799B1 (fi)
BR (1) BR9507327A (fi)
CA (1) CA2188147C (fi)
CZ (1) CZ289528B6 (fi)
DE (1) DE69532608T2 (fi)
DK (1) DK0758897T3 (fi)
EE (1) EE9600156A (fi)
ES (1) ES2217279T3 (fi)
FI (1) FI964218A (fi)
HK (1) HK1011294A1 (fi)
HU (1) HUT75331A (fi)
NO (1) NO317727B1 (fi)
NZ (1) NZ284357A (fi)
OA (1) OA10464A (fi)
PL (1) PL182942B1 (fi)
PT (1) PT758897E (fi)
RO (1) RO119225B1 (fi)
RU (1) RU2166319C2 (fi)
SI (1) SI9520055A (fi)
SK (1) SK284039B6 (fi)
WO (1) WO1995028160A1 (fi)

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CA2188147A1 (en) 1995-10-26
AU2294995A (en) 1995-11-10
NO964438L (no) 1996-10-18
CZ289528B6 (cs) 2002-02-13
OA10464A (en) 2002-04-03
EP0758897A1 (en) 1997-02-26
AP699A (en) 1998-12-01
ES2217279T3 (es) 2004-11-01
US5561134A (en) 1996-10-01
BR9507327A (pt) 1997-10-07
PL316961A1 (en) 1997-02-17
SK134096A3 (en) 1997-05-07
FI964218A0 (fi) 1996-10-18
EP0758897B1 (en) 2004-02-25
AP9600904A0 (en) 1997-01-31
BG100963A (en) 1997-08-29
CN1086704C (zh) 2002-06-26
EP1006115A3 (en) 2000-06-28
DK0758897T3 (da) 2004-05-03
PL182942B1 (pl) 2002-05-31
PT758897E (pt) 2004-07-30
CZ303296A3 (en) 1997-05-14
NO317727B1 (no) 2004-12-13
DE69532608T2 (de) 2005-01-05
EP1006115A2 (en) 2000-06-07
CN1148811A (zh) 1997-04-30
WO1995028160A1 (en) 1995-10-26
NO964438D0 (no) 1996-10-18
SI9520055A (en) 1997-06-30
BG63799B1 (bg) 2003-01-31
JPH09512020A (ja) 1997-12-02
RU2166319C2 (ru) 2001-05-10
HK1011294A1 (en) 1999-07-09
KR970702045A (ko) 1997-05-13
ATE260106T1 (de) 2004-03-15
CA2188147C (en) 2001-04-03
DE69532608D1 (de) 2004-04-01
NZ284357A (en) 2001-06-29
HU9602829D0 (en) 1996-12-30
US5736554A (en) 1998-04-07
EE9600156A (et) 1997-06-16
AU684635B2 (en) 1997-12-18
EP0758897A4 (en) 1997-11-19
HUT75331A (en) 1997-05-28
SK284039B6 (sk) 2004-08-03
RO119225B1 (ro) 2004-06-30
MX9604999A (es) 1998-05-31

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