FI960616A7 - 1-(2-(substituoitu-vinyyli))-3,4-dihydro-5H-2,3-bentsodiatsepiinijohdannaiset - Google Patents

1-(2-(substituoitu-vinyyli))-3,4-dihydro-5H-2,3-bentsodiatsepiinijohdannaiset Download PDF

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Publication number
FI960616A7
FI960616A7 FI960616A FI960616A FI960616A7 FI 960616 A7 FI960616 A7 FI 960616A7 FI 960616 A FI960616 A FI 960616A FI 960616 A FI960616 A FI 960616A FI 960616 A7 FI960616 A7 FI 960616A7
Authority
FI
Finland
Prior art keywords
dihydro
vinyl
substituted
benzodiazepine derivatives
benzodiazepine
Prior art date
Application number
FI960616A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI960616A0 (fi
Inventor
Pal Vago
Jozsef Reiter
Istvan Gyertyan
Gabor Gigler
Ferenc Andrasi
Anna Bakonyi
Pal Berzsenyi
Peter Botka
Faiglne Erzsebet Birkas
Tamas Hamori
Edit Horvath
Katalin Horvath
Jenoe Koeroesi
Gyoergyne Mate
Imre Moravcsik
Gyoergy Somogyi
Eszter Szentkuti
Gabor Zolyomi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FI960616A0 publication Critical patent/FI960616A0/fi
Publication of FI960616A7 publication Critical patent/FI960616A7/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI960616A 1995-02-09 1996-02-09 1-(2-(substituoitu-vinyyli))-3,4-dihydro-5H-2,3-bentsodiatsepiinijohdannaiset FI960616A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9500386A HU224435B1 (hu) 1995-02-09 1995-02-09 Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények

Publications (2)

Publication Number Publication Date
FI960616A0 FI960616A0 (fi) 1996-02-09
FI960616A7 true FI960616A7 (fi) 1996-08-10

Family

ID=10986432

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960616A FI960616A7 (fi) 1995-02-09 1996-02-09 1-(2-(substituoitu-vinyyli))-3,4-dihydro-5H-2,3-bentsodiatsepiinijohdannaiset

Country Status (18)

Country Link
US (1) US6075018A (cs)
JP (1) JP3354375B2 (cs)
KR (1) KR960031444A (cs)
BE (1) BE1009852A3 (cs)
CA (1) CA2169112A1 (cs)
CZ (1) CZ291218B6 (cs)
ES (1) ES2111492B1 (cs)
FI (1) FI960616A7 (cs)
FR (1) FR2730490B1 (cs)
GB (1) GB2297749B (cs)
HR (1) HRP960065A2 (cs)
HU (1) HU224435B1 (cs)
IT (1) IT1282591B1 (cs)
PL (1) PL312707A1 (cs)
RU (1) RU2155757C2 (cs)
SK (1) SK281482B6 (cs)
UA (1) UA45954C2 (cs)
YU (1) YU8396A (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL157873A0 (en) * 2001-04-12 2004-03-28 Hoffmann La Roche DIHYDRO-BENZO [b] [1,4] DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
CA2510275A1 (en) * 2002-12-03 2004-08-19 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
JP2006510634A (ja) * 2002-12-03 2006-03-30 ヴェラ ファーマスーティカルズ インコーポレイテッド １−（３，４−ジメトキシフェニル）−４−メチル−５−エチル−７−メトキシ−８−ヒドロキシ−５ｈ−２，３−ベンゾジアゼピンの製薬組成物及びその用途
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
PL1833815T3 (pl) * 2004-12-30 2011-03-31 Inst Farmaceutyczny Sposób wytwarzania zasady imatinibu
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU362013A1 (ru) * 1969-11-01 1972-12-13 Ростовский Ордена Трудового Красного Знамени Государственный Университет Всесоюзная i
BE761315A (cs) * 1970-01-12 1971-07-07 S M B Anciens Etablissements J
SU484873A1 (ru) * 1974-01-23 1975-09-25 Одесский Ордена Трудового Красного Знамени Государственный Университет Им.И.И.Мечникова Вещество,обладающее транквилизирующей снотворной и противосудорожной активностью
JPS5919099B2 (ja) * 1974-03-20 1984-05-02 藤沢薬品工業株式会社 ２−置換チオ−１，４−ベンゾジアゼピン誘導体の製造法
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
SU953819A1 (ru) * 1980-08-25 1991-09-23 Физико-химический институт АН УССР 1-(Гидразинокарбонил)алкил-1,2-дигидро-3Н-1,4-бенздиазепин-2-оны, обладающие транквилизирующими и противосудорожными свойствами
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
DE3402507A1 (de) * 1984-01-25 1985-08-01 Fa. Paliz Peter M. Forrer, Basel Arzneimittel
HU195788B (en) * 1986-05-21 1988-07-28 Gyogyszerkutato Intezet Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IT1282591B1 (it) 1998-03-31
BE1009852A3 (fr) 1997-10-07
CA2169112A1 (en) 1996-08-10
US6075018A (en) 2000-06-13
JPH08283247A (ja) 1996-10-29
GB9602690D0 (en) 1996-04-10
CZ37796A3 (en) 1996-08-14
FR2730490B1 (fr) 1997-04-18
YU8396A (sh) 1998-12-23
SK281482B6 (sk) 2001-04-09
CZ291218B6 (cs) 2003-01-15
GB2297749B (en) 1998-07-01
ITMI960245A0 (cs) 1996-02-09
UA45954C2 (uk) 2002-05-15
ITMI960245A1 (it) 1997-08-09
PL312707A1 (en) 1996-08-19
HU224435B1 (hu) 2005-10-28
FR2730490A1 (fr) 1996-08-14
JP3354375B2 (ja) 2002-12-09
RU2155757C2 (ru) 2000-09-10
FI960616A0 (fi) 1996-02-09
ES2111492A1 (es) 1998-03-01
ES2111492B1 (es) 1999-07-01
KR960031444A (ko) 1996-09-17
HRP960065A2 (en) 1997-12-31
SK16896A3 (en) 1996-10-02
GB2297749A (en) 1996-08-14
HU9500386D0 (en) 1995-03-28

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