FR2730490B1 - Derives 1-(2-(vinyl-substitues))-3,4-dihydro-5h-2,3- benzodiazepine - Google Patents
Derives 1-(2-(vinyl-substitues))-3,4-dihydro-5h-2,3- benzodiazepineInfo
- Publication number
- FR2730490B1 FR2730490B1 FR9601551A FR9601551A FR2730490B1 FR 2730490 B1 FR2730490 B1 FR 2730490B1 FR 9601551 A FR9601551 A FR 9601551A FR 9601551 A FR9601551 A FR 9601551A FR 2730490 B1 FR2730490 B1 FR 2730490B1
- Authority
- FR
- France
- Prior art keywords
- substitues
- benzodiazepine
- dihydro
- vinyl
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9500386A HU224435B1 (hu) | 1995-02-09 | 1995-02-09 | Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2730490A1 FR2730490A1 (fr) | 1996-08-14 |
FR2730490B1 true FR2730490B1 (fr) | 1997-04-18 |
Family
ID=10986432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9601551A Expired - Fee Related FR2730490B1 (fr) | 1995-02-09 | 1996-02-08 | Derives 1-(2-(vinyl-substitues))-3,4-dihydro-5h-2,3- benzodiazepine |
Country Status (18)
Country | Link |
---|---|
US (1) | US6075018A (fr) |
JP (1) | JP3354375B2 (fr) |
KR (1) | KR960031444A (fr) |
BE (1) | BE1009852A3 (fr) |
CA (1) | CA2169112A1 (fr) |
CZ (1) | CZ291218B6 (fr) |
ES (1) | ES2111492B1 (fr) |
FI (1) | FI960616A (fr) |
FR (1) | FR2730490B1 (fr) |
GB (1) | GB2297749B (fr) |
HR (1) | HRP960065A2 (fr) |
HU (1) | HU224435B1 (fr) |
IT (1) | IT1282591B1 (fr) |
PL (1) | PL312707A1 (fr) |
RU (1) | RU2155757C2 (fr) |
SK (1) | SK281482B6 (fr) |
UA (1) | UA45954C2 (fr) |
YU (1) | YU8396A (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6649607B2 (en) | 2001-05-18 | 2003-11-18 | Vela Pharmaceuticals, Inc. | Compositions and methods for treating or preventing convulsions or seizures |
MXPA05005895A (es) * | 2002-12-03 | 2006-02-08 | Vela Pharmaceuticals Inc | Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma. |
CA2510275A1 (fr) * | 2002-12-03 | 2004-08-19 | Vela Pharmaceuticals, Inc. | Composition pharmaceutique de 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine et utilisations de celle-ci |
US6864251B2 (en) * | 2002-12-03 | 2005-03-08 | Vela Pharmaceuticals, Inc. | Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines |
US6638928B1 (en) | 2002-12-03 | 2003-10-28 | Vela Pharmaceuticals, Inc. | Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines |
US7022700B2 (en) * | 2002-12-03 | 2006-04-04 | Vela Pharmaceuticals, Inc. | Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines |
US20040152694A1 (en) * | 2003-02-04 | 2004-08-05 | Istvan Kurucz | Methods and compositions for treating inflammatory disorders of the airways |
US20040224943A1 (en) * | 2003-02-19 | 2004-11-11 | Leventer Steven M. | Method of lowering body temperature with (R) - 2,3-benzodiazepines |
PL1833815T3 (pl) * | 2004-12-30 | 2011-03-31 | Inst Farmaceutyczny | Sposób wytwarzania zasady imatinibu |
EP2338492A1 (fr) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Procédés et compositions pour le traitement de la maladie d'Alzheimer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE761315A (fr) * | 1970-01-12 | 1971-07-07 | S M B Anciens Etablissements J | |
HU179018B (en) * | 1978-10-19 | 1982-08-28 | Gyogyszerkutato Intezet | Process for producing new 5h-2,3-benzodiazepine derivatives |
HU186760B (en) * | 1981-03-12 | 1985-09-30 | Gyogyszerkutato Intezet | Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives |
HU195788B (en) * | 1986-05-21 | 1988-07-28 | Gyogyszerkutato Intezet | Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them |
-
1995
- 1995-02-09 HU HU9500386A patent/HU224435B1/hu active IP Right Grant
-
1996
- 1996-02-07 SK SK168-96A patent/SK281482B6/sk unknown
- 1996-02-08 PL PL96312707A patent/PL312707A1/xx unknown
- 1996-02-08 RU RU96102418/04A patent/RU2155757C2/ru active
- 1996-02-08 FR FR9601551A patent/FR2730490B1/fr not_active Expired - Fee Related
- 1996-02-08 UA UA96020483A patent/UA45954C2/uk unknown
- 1996-02-08 BE BE9600110A patent/BE1009852A3/fr not_active IP Right Cessation
- 1996-02-08 CZ CZ1996377A patent/CZ291218B6/cs not_active IP Right Cessation
- 1996-02-08 CA CA002169112A patent/CA2169112A1/fr not_active Abandoned
- 1996-02-08 ES ES09600303A patent/ES2111492B1/es not_active Expired - Fee Related
- 1996-02-08 HR HRP9500386A patent/HRP960065A2/hr not_active Application Discontinuation
- 1996-02-09 YU YU8396A patent/YU8396A/sh unknown
- 1996-02-09 IT IT96MI000245A patent/IT1282591B1/it active IP Right Grant
- 1996-02-09 KR KR1019960003129A patent/KR960031444A/ko not_active Application Discontinuation
- 1996-02-09 GB GB9602690A patent/GB2297749B/en not_active Expired - Fee Related
- 1996-02-09 FI FI960616A patent/FI960616A/fi unknown
- 1996-02-09 JP JP02396796A patent/JP3354375B2/ja not_active Expired - Fee Related
- 1996-02-09 US US08/599,235 patent/US6075018A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PL312707A1 (en) | 1996-08-19 |
UA45954C2 (uk) | 2002-05-15 |
CA2169112A1 (fr) | 1996-08-10 |
FI960616A0 (fi) | 1996-02-09 |
HU224435B1 (hu) | 2005-10-28 |
SK281482B6 (sk) | 2001-04-09 |
FR2730490A1 (fr) | 1996-08-14 |
YU8396A (sh) | 1998-12-23 |
ES2111492B1 (es) | 1999-07-01 |
ITMI960245A0 (fr) | 1996-02-09 |
ITMI960245A1 (it) | 1997-08-09 |
FI960616A (fi) | 1996-08-10 |
HRP960065A2 (en) | 1997-12-31 |
KR960031444A (ko) | 1996-09-17 |
US6075018A (en) | 2000-06-13 |
GB9602690D0 (en) | 1996-04-10 |
GB2297749B (en) | 1998-07-01 |
ES2111492A1 (es) | 1998-03-01 |
JP3354375B2 (ja) | 2002-12-09 |
GB2297749A (en) | 1996-08-14 |
BE1009852A3 (fr) | 1997-10-07 |
JPH08283247A (ja) | 1996-10-29 |
SK16896A3 (en) | 1996-10-02 |
CZ37796A3 (en) | 1996-08-14 |
RU2155757C2 (ru) | 2000-09-10 |
IT1282591B1 (it) | 1998-03-31 |
CZ291218B6 (cs) | 2003-01-15 |
HU9500386D0 (en) | 1995-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |