FI953506A - Monia lääkeaineita vastaan vastustuskykyisten kasvainten lääkkeinä käyttökelpoiset diaryylialkyylipiperidiinit - Google Patents
Monia lääkeaineita vastaan vastustuskykyisten kasvainten lääkkeinä käyttökelpoiset diaryylialkyylipiperidiinit Download PDFInfo
- Publication number
- FI953506A FI953506A FI953506A FI953506A FI953506A FI 953506 A FI953506 A FI 953506A FI 953506 A FI953506 A FI 953506A FI 953506 A FI953506 A FI 953506A FI 953506 A FI953506 A FI 953506A
- Authority
- FI
- Finland
- Prior art keywords
- pct
- tumors
- diarylalkylpiperidines
- medicines
- resistant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US656993A | 1993-01-21 | 1993-01-21 | |
| PCT/US1993/012300 WO1994017040A1 (en) | 1993-01-21 | 1993-12-17 | Diarylalkyl piperidines useful as multi-drug resistant tumor agents |
| US9312300 | 1993-12-17 | ||
| US656993 | 1996-05-28 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI953506A0 FI953506A0 (fi) | 1995-07-20 |
| FI953506A true FI953506A (fi) | 1995-07-20 |
| FI112474B FI112474B (fi) | 2003-12-15 |
Family
ID=21721516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI953506A FI112474B (fi) | 1993-01-21 | 1995-07-20 | Menetelmä kasvainlääkkeinä käyttökelpoisten diaryylialkyylipiperidiiniyhdisteiden valmistamiseksi |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5648365A (fi) |
| EP (1) | EP0680470B1 (fi) |
| JP (1) | JP3398748B2 (fi) |
| KR (1) | KR100377280B1 (fi) |
| AT (1) | ATE150748T1 (fi) |
| AU (1) | AU679723B2 (fi) |
| CA (1) | CA2152794C (fi) |
| DE (1) | DE69309310T2 (fi) |
| DK (1) | DK0680470T3 (fi) |
| ES (1) | ES2102830T3 (fi) |
| FI (1) | FI112474B (fi) |
| GR (1) | GR3023188T3 (fi) |
| HU (1) | HUT72078A (fi) |
| IL (1) | IL108369A (fi) |
| MX (1) | MX9400563A (fi) |
| NO (1) | NO305166B1 (fi) |
| NZ (1) | NZ261414A (fi) |
| TW (1) | TW243445B (fi) |
| WO (1) | WO1994017040A1 (fi) |
| ZA (1) | ZA94317B (fi) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU662602B2 (en) * | 1992-02-06 | 1995-09-07 | Merrell Dow Pharmaceuticals Inc. | Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives |
| AU6366000A (en) * | 1999-07-23 | 2001-02-13 | Colorado State University Research Foundation | Multidrug resistance pump inhibitors and uses thereof |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US20030109448A1 (en) * | 2001-11-07 | 2003-06-12 | Crowley Kathleen S. | Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells |
| KR100656490B1 (ko) | 2001-11-26 | 2006-12-12 | 삼성에스디아이 주식회사 | 풀칼라 유기전계 발광표시소자 및 그의 제조방법 |
| US8153184B2 (en) * | 2001-11-26 | 2012-04-10 | Samsung Mobile Display Co., Ltd. | Organic EL display device and method of manufacturing the same |
| PT3732994T (pt) | 2013-02-08 | 2022-12-02 | Gen Mills Inc | Produtos alimentares com reduzido teor de sódio |
| CN110372571B (zh) * | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1049377B (de) * | 1952-04-03 | 1959-01-29 | Abbott Laboratories, North Chicago, 111. (V. St. A.) | Verfahren zur Herstellung von substituierten Vinylpiperidinen |
| US2898339A (en) * | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US3956296A (en) * | 1974-12-11 | 1976-05-11 | A. H. Robins Company, Incorporated | 1-Substituted-4-benzylpiperidines |
| US4035372A (en) * | 1976-08-13 | 1977-07-12 | G. D. Searle & Co. | 4-{[4-(Diphenylmethyl)-1-piperidinyl]methyl}benzenamines |
| EP0228893A3 (en) * | 1985-12-20 | 1990-01-03 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl group in allergy treatment |
| US4851423A (en) * | 1986-12-10 | 1989-07-25 | Schering Corporation | Pharmaceutically active compounds |
| US4990511A (en) * | 1988-08-03 | 1991-02-05 | Takeda Chemical Industries, Ltd. | Amide compounds, their production and use |
| DE69003200T2 (de) * | 1989-06-19 | 1994-01-20 | Wellcome Found | Arylsubstituierte Aminderivate verwendbar in der Krebstherapie. |
| GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
| EP0467435A3 (en) * | 1990-07-19 | 1992-04-01 | Akzo N.V. | Benzhydryl derivatives having calmodulin inhibitor properties |
| ES2112268T3 (es) * | 1990-08-14 | 1998-04-01 | Hoechst Marion Roussel Inc | Nuevos 19-nor-esteroides que tienen en posicion 11beta una cadena carbonada que comprende una funcion amida, su preparacion, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen. |
| AU662602B2 (en) * | 1992-02-06 | 1995-09-07 | Merrell Dow Pharmaceuticals Inc. | Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives |
-
1993
- 1993-12-17 DK DK94906446.3T patent/DK0680470T3/da active
- 1993-12-17 AU AU60148/94A patent/AU679723B2/en not_active Ceased
- 1993-12-17 DE DE69309310T patent/DE69309310T2/de not_active Expired - Fee Related
- 1993-12-17 AT AT94906446T patent/ATE150748T1/de not_active IP Right Cessation
- 1993-12-17 JP JP51701194A patent/JP3398748B2/ja not_active Expired - Fee Related
- 1993-12-17 HU HU9502195A patent/HUT72078A/hu unknown
- 1993-12-17 WO PCT/US1993/012300 patent/WO1994017040A1/en active IP Right Grant
- 1993-12-17 US US08/481,538 patent/US5648365A/en not_active Expired - Fee Related
- 1993-12-17 ES ES94906446T patent/ES2102830T3/es not_active Expired - Lifetime
- 1993-12-17 KR KR1019950702950A patent/KR100377280B1/ko not_active IP Right Cessation
- 1993-12-17 NZ NZ261414A patent/NZ261414A/en unknown
- 1993-12-17 CA CA002152794A patent/CA2152794C/en not_active Expired - Fee Related
- 1993-12-17 EP EP94906446A patent/EP0680470B1/en not_active Expired - Lifetime
-
1994
- 1994-01-17 ZA ZA94317A patent/ZA94317B/xx unknown
- 1994-01-18 TW TW083100396A patent/TW243445B/zh active
- 1994-01-19 IL IL10836994A patent/IL108369A/en not_active IP Right Cessation
- 1994-01-20 MX MX9400563A patent/MX9400563A/es not_active IP Right Cessation
-
1995
- 1995-07-20 NO NO952885A patent/NO305166B1/no not_active IP Right Cessation
- 1995-07-20 FI FI953506A patent/FI112474B/fi active
-
1997
- 1997-04-21 GR GR970400848T patent/GR3023188T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6014894A (en) | 1994-08-15 |
| CA2152794A1 (en) | 1994-08-04 |
| HU9502195D0 (en) | 1995-09-28 |
| JP3398748B2 (ja) | 2003-04-21 |
| IL108369A0 (en) | 1994-04-12 |
| US5648365A (en) | 1997-07-15 |
| GR3023188T3 (en) | 1997-07-30 |
| NO305166B1 (no) | 1999-04-12 |
| DE69309310D1 (de) | 1997-04-30 |
| NO952885L (no) | 1995-09-20 |
| ZA94317B (en) | 1994-08-18 |
| EP0680470B1 (en) | 1997-03-26 |
| FI953506A0 (fi) | 1995-07-20 |
| NZ261414A (en) | 1997-06-24 |
| FI112474B (fi) | 2003-12-15 |
| IL108369A (en) | 1999-08-17 |
| HUT72078A (en) | 1996-03-28 |
| KR100377280B1 (ko) | 2003-07-18 |
| DK0680470T3 (fi) | 1997-04-28 |
| ATE150748T1 (de) | 1997-04-15 |
| DE69309310T2 (de) | 1997-11-06 |
| MX9400563A (es) | 1994-07-29 |
| AU679723B2 (en) | 1997-07-10 |
| CA2152794C (en) | 1999-04-06 |
| KR960700230A (ko) | 1996-01-19 |
| TW243445B (fi) | 1995-03-21 |
| EP0680470A1 (en) | 1995-11-08 |
| JPH08505870A (ja) | 1996-06-25 |
| NO952885D0 (no) | 1995-07-20 |
| ES2102830T3 (es) | 1997-08-01 |
| WO1994017040A1 (en) | 1994-08-04 |
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