TW243445B - - Google Patents

Info

Publication number
TW243445B
TW243445B TW083100396A TW83100396A TW243445B TW 243445 B TW243445 B TW 243445B TW 083100396 A TW083100396 A TW 083100396A TW 83100396 A TW83100396 A TW 83100396A TW 243445 B TW243445 B TW 243445B
Authority
TW
Taiwan
Prior art keywords
pct
sec
date
tumors
pub
Prior art date
Application number
TW083100396A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of TW243445B publication Critical patent/TW243445B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
TW083100396A 1993-01-21 1994-01-18 TW243445B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US656993A 1993-01-21 1993-01-21

Publications (1)

Publication Number Publication Date
TW243445B true TW243445B (zh) 1995-03-21

Family

ID=21721516

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083100396A TW243445B (zh) 1993-01-21 1994-01-18

Country Status (20)

Country Link
US (1) US5648365A (zh)
EP (1) EP0680470B1 (zh)
JP (1) JP3398748B2 (zh)
KR (1) KR100377280B1 (zh)
AT (1) ATE150748T1 (zh)
AU (1) AU679723B2 (zh)
CA (1) CA2152794C (zh)
DE (1) DE69309310T2 (zh)
DK (1) DK0680470T3 (zh)
ES (1) ES2102830T3 (zh)
FI (1) FI112474B (zh)
GR (1) GR3023188T3 (zh)
HU (1) HUT72078A (zh)
IL (1) IL108369A (zh)
MX (1) MX9400563A (zh)
NO (1) NO305166B1 (zh)
NZ (1) NZ261414A (zh)
TW (1) TW243445B (zh)
WO (1) WO1994017040A1 (zh)
ZA (1) ZA94317B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0643693T3 (da) * 1992-02-06 1999-11-29 Merrell Pharma Inc Reversering af multi-lægemiddelresistens med triphenyl-piperidin-derivater
WO2001007034A1 (en) * 1999-07-23 2001-02-01 Colorado State University Research Foundation Multidrug resistance pump inhibitors and uses thereof
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US20030109448A1 (en) * 2001-11-07 2003-06-12 Crowley Kathleen S. Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells
KR100656490B1 (ko) * 2001-11-26 2006-12-12 삼성에스디아이 주식회사 풀칼라 유기전계 발광표시소자 및 그의 제조방법
US8153184B2 (en) * 2001-11-26 2012-04-10 Samsung Mobile Display Co., Ltd. Organic EL display device and method of manufacturing the same
PT2956440T (pt) 2013-02-08 2018-05-08 Gen Mills Inc Produtos alimentares com baixo teor de sódio
CN110372571B (zh) * 2018-04-12 2022-11-15 中国科学院大连化学物理研究所 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049377B (de) * 1952-04-03 1959-01-29 Abbott Laboratories, North Chicago, 111. (V. St. A.) Verfahren zur Herstellung von substituierten Vinylpiperidinen
US2898339A (en) * 1957-07-29 1959-08-04 Wm S Merrell Co N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US3956296A (en) * 1974-12-11 1976-05-11 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines
US4035372A (en) * 1976-08-13 1977-07-12 G. D. Searle & Co. 4-{[4-(Diphenylmethyl)-1-piperidinyl]methyl}benzenamines
EP0228893A3 (en) * 1985-12-20 1990-01-03 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl group in allergy treatment
US4851423A (en) * 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
US4990511A (en) * 1988-08-03 1991-02-05 Takeda Chemical Industries, Ltd. Amide compounds, their production and use
HUT59377A (en) * 1989-06-19 1992-05-28 Wellcome Found Process for producing drugs containing new aromatic rings
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
EP0467435A3 (en) * 1990-07-19 1992-04-01 Akzo N.V. Benzhydryl derivatives having calmodulin inhibitor properties
ATE162797T1 (de) * 1990-08-14 1998-02-15 Roussel Uclaf Neue 19-nor steroide, die eine amid tragende gruppe in der 11-beta-stelle haben, ihre herstellung, ihre verwendung als medikamente und pharmazeutische präparate davon
DK0643693T3 (da) * 1992-02-06 1999-11-29 Merrell Pharma Inc Reversering af multi-lægemiddelresistens med triphenyl-piperidin-derivater

Also Published As

Publication number Publication date
MX9400563A (es) 1994-07-29
AU679723B2 (en) 1997-07-10
CA2152794A1 (en) 1994-08-04
IL108369A (en) 1999-08-17
DE69309310D1 (de) 1997-04-30
DE69309310T2 (de) 1997-11-06
NO952885D0 (no) 1995-07-20
WO1994017040A1 (en) 1994-08-04
EP0680470B1 (en) 1997-03-26
ES2102830T3 (es) 1997-08-01
AU6014894A (en) 1994-08-15
KR960700230A (ko) 1996-01-19
ZA94317B (en) 1994-08-18
ATE150748T1 (de) 1997-04-15
HU9502195D0 (en) 1995-09-28
JPH08505870A (ja) 1996-06-25
FI112474B (fi) 2003-12-15
HUT72078A (en) 1996-03-28
NO305166B1 (no) 1999-04-12
DK0680470T3 (zh) 1997-04-28
GR3023188T3 (en) 1997-07-30
IL108369A0 (en) 1994-04-12
FI953506A (fi) 1995-07-20
NZ261414A (en) 1997-06-24
NO952885L (no) 1995-09-20
FI953506A0 (fi) 1995-07-20
CA2152794C (en) 1999-04-06
US5648365A (en) 1997-07-15
EP0680470A1 (en) 1995-11-08
JP3398748B2 (ja) 2003-04-21
KR100377280B1 (ko) 2003-07-18

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