FI952458A - Dimetyylibentsofuraanien ja dimetyylibentsopyraanien käyttö 5-HT3-antagonisteina - Google Patents
Dimetyylibentsofuraanien ja dimetyylibentsopyraanien käyttö 5-HT3-antagonisteina Download PDFInfo
- Publication number
- FI952458A FI952458A FI952458A FI952458A FI952458A FI 952458 A FI952458 A FI 952458A FI 952458 A FI952458 A FI 952458A FI 952458 A FI952458 A FI 952458A FI 952458 A FI952458 A FI 952458A
- Authority
- FI
- Finland
- Prior art keywords
- pct
- date jun
- represents hydrogen
- sec
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Otolaryngology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97901392A | 1992-11-20 | 1992-11-20 | |
| PCT/EP1993/003206 WO1994012494A1 (en) | 1992-11-20 | 1993-11-15 | Use of dimethylbenzofurans and dimethylbenzopyrans as 5-ht3 antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI952458A true FI952458A (fi) | 1995-05-19 |
| FI952458A0 FI952458A0 (fi) | 1995-05-19 |
Family
ID=25526607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI952458A FI952458A0 (fi) | 1992-11-20 | 1995-05-19 | Dimetyylibentsofuraanien ja dimetyylibentsopyraanien käyttö 5-HT3-antagonisteina |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US5674868A (fi) |
| EP (1) | EP0669919B1 (fi) |
| JP (1) | JP2830952B2 (fi) |
| KR (1) | KR0166661B1 (fi) |
| AT (1) | ATE176232T1 (fi) |
| AU (1) | AU680640B2 (fi) |
| BG (1) | BG62489B1 (fi) |
| BR (1) | BR9307477A (fi) |
| CA (1) | CA2149044C (fi) |
| CZ (1) | CZ287262B6 (fi) |
| DE (1) | DE69323322T2 (fi) |
| DK (1) | DK0669919T3 (fi) |
| ES (1) | ES2129615T3 (fi) |
| FI (1) | FI952458A0 (fi) |
| GR (1) | GR3029831T3 (fi) |
| HU (2) | HUT72740A (fi) |
| IL (3) | IL119273A (fi) |
| LV (1) | LV10956B (fi) |
| MX (1) | MX9307257A (fi) |
| NO (2) | NO307690B1 (fi) |
| NZ (1) | NZ257854A (fi) |
| OA (1) | OA10158A (fi) |
| PL (1) | PL176051B1 (fi) |
| RO (1) | RO115160B1 (fi) |
| RU (1) | RU2116072C1 (fi) |
| SG (1) | SG47488A1 (fi) |
| SK (1) | SK282378B6 (fi) |
| TW (1) | TW294595B (fi) |
| UA (1) | UA49792C2 (fi) |
| WO (1) | WO1994012494A1 (fi) |
| ZA (1) | ZA938676B (fi) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| DE69816060T2 (de) * | 1997-04-18 | 2004-04-22 | Janssen Pharmaceutica N.V. | Verwendung von 5ht3 antagonisten zum fördern der darmspülung |
| JP3529102B2 (ja) * | 1997-07-11 | 2004-05-24 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノート シヤツプ | ５−ｈｔ３および５−ｈｔ４介在性障害に有用な（＋）−ノルシサプリド |
| US6239122B1 (en) * | 2000-01-05 | 2001-05-29 | Joy Ann Steele | Method of treatment of nausea, vomiting, and other disorders using estrogens |
| DE602004022819D1 (de) * | 2003-06-06 | 2009-10-08 | Vertex Pharma | Von atp-bindende kassette transportern |
| WO2005054201A1 (en) | 2003-11-20 | 2005-06-16 | Janssen Pharmaceutica N.V. | 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors |
| US7928104B2 (en) | 2003-11-20 | 2011-04-19 | Dominique Jean-Pierre Mabire | 7-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors |
| UA88012C2 (uk) | 2004-06-30 | 2009-09-10 | Янссен Фармацевтика Н.В. | Похідні хіназоліндіону як інгібітори parp |
| EA014955B1 (ru) | 2004-06-30 | 2011-04-29 | Янссен Фармацевтика Н. В. | Производные фталазина в качестве ингибиторов parp |
| ATE498613T1 (de) | 2004-06-30 | 2011-03-15 | Janssen Pharmaceutica Nv | Chinazolinonderivate als parp-hemmer |
| EP2134691B1 (en) | 2007-03-08 | 2012-01-25 | Janssen Pharmaceutica, N.V. | Quinolinone derivatives as parp and tank inhibitors |
| PL2215075T3 (pl) | 2007-10-26 | 2014-04-30 | Janssen Pharmaceutica Nv | Pochodne chinolinonu jako inhibitory PARP |
| AU2009228945B2 (en) | 2008-03-27 | 2013-05-02 | Janssen Pharmaceutica Nv | Quinazolinone derivatives as tubulin polymerization inhibitors |
| WO2009118382A1 (en) | 2008-03-27 | 2009-10-01 | Janssen Pharmaceutica Nv | Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as parp and tubulin polymerization inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
| ZW12187A1 (en) * | 1986-07-03 | 1989-02-01 | Janssen Pharmaceutica Nv | 4-(aroylamino)piperidinebutanamide derivatives |
| CA1317940C (en) * | 1987-09-25 | 1993-05-18 | Georges H. P. Van Daele | Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| GB9005014D0 (en) * | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
-
1993
- 1993-11-03 TW TW082109153A patent/TW294595B/zh active
- 1993-11-15 AT AT94900151T patent/ATE176232T1/de not_active IP Right Cessation
- 1993-11-15 US US08/416,914 patent/US5674868A/en not_active Expired - Fee Related
- 1993-11-15 ES ES94900151T patent/ES2129615T3/es not_active Expired - Lifetime
- 1993-11-15 CZ CZ19951258A patent/CZ287262B6/cs not_active IP Right Cessation
- 1993-11-15 SK SK675-95A patent/SK282378B6/sk unknown
- 1993-11-15 BR BR9307477A patent/BR9307477A/pt not_active Application Discontinuation
- 1993-11-15 KR KR1019950701615A patent/KR0166661B1/ko not_active IP Right Cessation
- 1993-11-15 JP JP6512708A patent/JP2830952B2/ja not_active Expired - Fee Related
- 1993-11-15 UA UA95048357A patent/UA49792C2/uk unknown
- 1993-11-15 RO RO95-00941A patent/RO115160B1/ro unknown
- 1993-11-15 CA CA002149044A patent/CA2149044C/en not_active Expired - Fee Related
- 1993-11-15 RU RU95113434A patent/RU2116072C1/ru not_active IP Right Cessation
- 1993-11-15 AU AU54659/94A patent/AU680640B2/en not_active Ceased
- 1993-11-15 WO PCT/EP1993/003206 patent/WO1994012494A1/en active IP Right Grant
- 1993-11-15 DE DE69323322T patent/DE69323322T2/de not_active Expired - Fee Related
- 1993-11-15 SG SG1996002238A patent/SG47488A1/en unknown
- 1993-11-15 PL PL93309045A patent/PL176051B1/pl not_active IP Right Cessation
- 1993-11-15 NZ NZ257854A patent/NZ257854A/en unknown
- 1993-11-15 HU HU9501476A patent/HUT72740A/hu unknown
- 1993-11-15 EP EP94900151A patent/EP0669919B1/en not_active Expired - Lifetime
- 1993-11-15 DK DK94900151T patent/DK0669919T3/da active
- 1993-11-18 IL IL11927393A patent/IL119273A/xx not_active IP Right Cessation
- 1993-11-18 IL IL11927396A patent/IL119273A0/xx unknown
- 1993-11-18 IL IL107654A patent/IL107654A/en not_active IP Right Cessation
- 1993-11-19 ZA ZA938676A patent/ZA938676B/xx unknown
- 1993-11-19 MX MX9307257A patent/MX9307257A/es unknown
-
1995
- 1995-04-20 BG BG99593A patent/BG62489B1/bg unknown
- 1995-05-19 NO NO951980A patent/NO307690B1/no unknown
- 1995-05-19 FI FI952458A patent/FI952458A0/fi unknown
- 1995-05-19 OA OA60663A patent/OA10158A/en unknown
- 1995-06-20 LV LVP-95-184A patent/LV10956B/en unknown
- 1995-06-30 HU HU95P/P00699P patent/HU211546A9/hu unknown
-
1997
- 1997-05-01 US US08/848,777 patent/US5863923A/en not_active Expired - Fee Related
-
1999
- 1999-03-31 GR GR990400922T patent/GR3029831T3/el unknown
- 1999-11-24 NO NO995762A patent/NO308530B1/no unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI952458A0 (fi) | Dimetyylibentsofuraanien ja dimetyylibentsopyraanien käyttö 5-HT3-antagonisteina | |
| GB9524157D0 (en) | Therapeutic agents | |
| GR3034769T3 (en) | Triazole antifungal agents. | |
| FI943931A0 (fi) | Indolijohdannaisia steroidi-5alfa-reduktaasin inhibiittoreina | |
| DK0871626T3 (da) | Triazoloner som apolipoprotein-B syntheseinhibitorer | |
| EE9600142A (et) | Helicobacter spp. vastased asoloonide derivaadid, nende valmistamise meetod ja kasutamine, vaheühendid, farmatseutiline kompositsioon ja selle valmistamise meetod ning terapeutiline kombinatsioon. | |
| LV11545A (lv) | Pozitivas inotropas un lusitropas iedarbibas pirolohinolinona atvasinajumi |