EE9600142A - Helicobacter spp. vastased asoloonide derivaadid, nende valmistamise meetod ja kasutamine, vaheühendid, farmatseutiline kompositsioon ja selle valmistamise meetod ning terapeutiline kombinatsioon. - Google Patents

Helicobacter spp. vastased asoloonide derivaadid, nende valmistamise meetod ja kasutamine, vaheühendid, farmatseutiline kompositsioon ja selle valmistamise meetod ning terapeutiline kombinatsioon.

Info

Publication number
EE9600142A
EE9600142A EE9600142A EE9600142A EE9600142A EE 9600142 A EE9600142 A EE 9600142A EE 9600142 A EE9600142 A EE 9600142A EE 9600142 A EE9600142 A EE 9600142A EE 9600142 A EE9600142 A EE 9600142A
Authority
EE
Estonia
Prior art keywords
image
pct
4alkyl
6alkyl
intermediates
Prior art date
Application number
EE9600142A
Other languages
English (en)
Inventor
Heeres Jan
Hector Mostmans Joseph
Jozef Maria Hendrickx Robert
Jozef Elisabeth Van Der Veken Louis
Antoine Stokbroekx Raymond
Jozef Maria Van Der Aa Marcel
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE9600142A publication Critical patent/EE9600142A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cephalosporin Compounds (AREA)
EE9600142A 1994-04-06 1995-03-29 Helicobacter spp. vastased asoloonide derivaadid, nende valmistamise meetod ja kasutamine, vaheühendid, farmatseutiline kompositsioon ja selle valmistamise meetod ning terapeutiline kombinatsioon. EE9600142A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94200938 1994-04-06
PCT/EP1995/001184 WO1995027704A1 (en) 1994-04-06 1995-03-29 Anti-helicobacter ester and carbamate derivatives of azolones

Publications (1)

Publication Number Publication Date
EE9600142A true EE9600142A (et) 1997-04-15

Family

ID=8216773

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600142A EE9600142A (et) 1994-04-06 1995-03-29 Helicobacter spp. vastased asoloonide derivaadid, nende valmistamise meetod ja kasutamine, vaheühendid, farmatseutiline kompositsioon ja selle valmistamise meetod ning terapeutiline kombinatsioon.

Country Status (20)

Country Link
US (1) US5710156A (et)
EP (1) EP0754180B1 (et)
JP (1) JPH09511513A (et)
CN (1) CN1145067A (et)
AT (1) ATE207910T1 (et)
AU (1) AU685935B2 (et)
BR (1) BR9507289A (et)
CA (1) CA2185552A1 (et)
CZ (1) CZ287596A3 (et)
DE (1) DE69523581T2 (et)
EE (1) EE9600142A (et)
FI (1) FI963995A (et)
HU (1) HUT76287A (et)
IL (1) IL113254A (et)
NO (1) NO964216L (et)
NZ (1) NZ283346A (et)
PL (1) PL316655A1 (et)
SK (1) SK127196A3 (et)
WO (1) WO1995027704A1 (et)
ZA (1) ZA952810B (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
US5202346A (en) * 1992-02-25 1993-04-13 American Home Products Corporation Piperidinyl and piperazinyl derivatives
TW279864B (et) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv

Also Published As

Publication number Publication date
AU685935B2 (en) 1998-01-29
JPH09511513A (ja) 1997-11-18
CA2185552A1 (en) 1995-10-19
ATE207910T1 (de) 2001-11-15
DE69523581T2 (de) 2002-07-11
SK127196A3 (en) 1997-05-07
NO964216D0 (no) 1996-10-04
AU2137195A (en) 1995-10-30
CN1145067A (zh) 1997-03-12
DE69523581D1 (de) 2001-12-06
FI963995A0 (fi) 1996-10-04
PL316655A1 (en) 1997-02-03
EP0754180A1 (en) 1997-01-22
BR9507289A (pt) 1997-09-23
EP0754180B1 (en) 2001-10-31
ZA952810B (en) 1996-10-07
HUT76287A (en) 1997-07-28
NZ283346A (en) 1997-05-26
NO964216L (no) 1996-10-04
IL113254A0 (en) 1995-07-31
CZ287596A3 (en) 1997-01-15
IL113254A (en) 1999-03-12
FI963995A (fi) 1996-10-04
US5710156A (en) 1998-01-20
MX9604610A (es) 1997-11-29
WO1995027704A1 (en) 1995-10-19
HU9602725D0 (en) 1996-11-28

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