FI931370A7 - Typpeä sisältävien, ei-aromaattisten heterosyklien analogeja, joissa o n fuusioitunut rengas - Google Patents

Typpeä sisältävien, ei-aromaattisten heterosyklien analogeja, joissa o n fuusioitunut rengas Download PDF

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Publication number
FI931370A7
FI931370A7 FI931370A FI931370A FI931370A7 FI 931370 A7 FI931370 A7 FI 931370A7 FI 931370 A FI931370 A FI 931370A FI 931370 A FI931370 A FI 931370A FI 931370 A7 FI931370 A7 FI 931370A7
Authority
FI
Finland
Prior art keywords
analogues
nitrogen
fused ring
aromatic heterocycles
heterocycles
Prior art date
Application number
FI931370A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI931370L (fi
FI931370A0 (fi
Inventor
Harry R Howard
Terry J Rosen
Manoj C Desai
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI931370A7 publication Critical patent/FI931370A7/fi
Publication of FI931370L publication Critical patent/FI931370L/fi
Publication of FI931370A0 publication Critical patent/FI931370A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Eye Examination Apparatus (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Electroluminescent Light Sources (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
FI931370A 1990-09-28 1991-08-20 Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring FI931370A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59042390A 1990-09-28 1990-09-28
PCT/US1991/005776 WO1992006079A1 (en) 1990-09-28 1991-08-20 Fused ring analogs of nitrogen containing nonaromatic heterocycles

Publications (3)

Publication Number Publication Date
FI931370A7 true FI931370A7 (fi) 1993-03-26
FI931370L FI931370L (fi) 1993-03-26
FI931370A0 FI931370A0 (fi) 1993-03-26

Family

ID=24362216

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931370A FI931370A0 (fi) 1990-09-28 1991-08-20 Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring

Country Status (22)

Country Link
EP (1) EP0550635B1 (enExample)
JP (1) JPH0772175B2 (enExample)
CN (1) CN1060285A (enExample)
AT (1) ATE121389T1 (enExample)
AU (1) AU651145B2 (enExample)
BR (1) BR9106905A (enExample)
CA (1) CA2089736A1 (enExample)
CZ (1) CZ387492A3 (enExample)
DE (1) DE69109125T2 (enExample)
DK (1) DK0550635T3 (enExample)
ES (1) ES2071334T3 (enExample)
FI (1) FI931370A0 (enExample)
HU (1) HUT68667A (enExample)
IE (1) IE66042B1 (enExample)
IL (1) IL99525A0 (enExample)
MX (1) MX9101274A (enExample)
NO (1) NO931151L (enExample)
PT (1) PT99064A (enExample)
TW (1) TW199144B (enExample)
WO (1) WO1992006079A1 (enExample)
YU (1) YU159291A (enExample)
ZA (1) ZA917744B (enExample)

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US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US6048859A (en) * 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
CA2141051A1 (en) * 1992-08-04 1994-02-17 Terry J. Rosen Substituted nitrogen-containing heterocycles
GB9216911D0 (en) * 1992-08-10 1992-09-23 Merck Sharp & Dohme Therapeutic agents
EP1114823A3 (en) * 1992-08-19 2001-07-18 Pfizer Inc. Substituted benzylamino nitrogen containing non-aromatic heterocycles
US5387595A (en) * 1992-08-26 1995-02-07 Merck & Co., Inc. Alicyclic compounds as tachykinin receptor antagonists
US5344830A (en) * 1992-12-10 1994-09-06 Merck & Co., Inc. N,N-diacylpiperazine tachykinin antagonists
PT675886E (pt) * 1992-12-10 2000-12-29 Pfizer Heterociclos nao aromaticos com substituintes aminometileno e sua utilizacao como antagonistas da substancia p
US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
US5854262A (en) * 1993-10-07 1998-12-29 Pfizer Inc. Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists
US5610165A (en) * 1994-02-17 1997-03-11 Merck & Co., Inc. N-acylpiperidine tachykinin antagonists
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FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
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US6245817B1 (en) 1997-02-14 2001-06-12 Bayer Corporation NPY5 receptor antagonists and methods for using same
JP2000510870A (ja) * 1997-02-14 2000-08-22 バイエル・コーポレーシヨン Ｎｐｙ５受容体アンタゴニストとしてのアミド類
US6048900A (en) * 1998-02-13 2000-04-11 Bayer Corporation Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
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ATE387429T1 (de) 1999-11-03 2008-03-15 Amr Technology Inc Arly- und heteroaryl-substituierte tetrahydroisoquinoline und ihre verwendung als hemmer der wiederaufnahme von norepinephrin, dopamin und serotonin
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
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US7119207B2 (en) 2000-04-10 2006-10-10 Pfizer Inc Benzoamide piperidine containing compounds and related compounds
CN100430401C (zh) 2000-07-11 2008-11-05 Amr科技公司 新的4-苯基取代的四氢异喹啉类化合物及其治疗用途
AU2002211621A1 (en) * 2000-10-10 2002-04-22 Calyx Therapeutics, Inc. Tricyclic compounds and uses thereof
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WO2006123182A2 (en) 2005-05-17 2006-11-23 Merck Sharp & Dohme Limited Cyclohexyl sulphones for treatment of cancer
DE102005027168A1 (de) * 2005-06-13 2006-12-14 Merck Patent Gmbh Tetrahydrochinoline
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KR20080048502A (ko) 2005-09-29 2008-06-02 머크 앤드 캄파니 인코포레이티드 멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체
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Also Published As

Publication number Publication date
CN1060285A (zh) 1992-04-15
IE913396A1 (en) 1992-04-08
HU9300898D0 (en) 1993-06-28
ES2071334T3 (es) 1995-06-16
ZA917744B (en) 1993-03-29
JPH06501267A (ja) 1994-02-10
IL99525A0 (en) 1992-08-18
BR9106905A (pt) 1993-08-17
AU8746391A (en) 1992-04-28
AU651145B2 (en) 1994-07-14
EP0550635A1 (en) 1993-07-14
DK0550635T3 (da) 1995-09-04
YU159291A (sh) 1994-01-20
HUT68667A (en) 1995-07-28
NO931151D0 (no) 1993-03-26
JPH0772175B2 (ja) 1995-08-02
FI931370L (fi) 1993-03-26
ATE121389T1 (de) 1995-05-15
WO1992006079A1 (en) 1992-04-16
CA2089736A1 (en) 1992-03-29
TW199144B (enExample) 1993-02-01
CZ387492A3 (en) 1994-02-16
DE69109125D1 (de) 1995-05-24
NO931151L (no) 1993-03-26
EP0550635B1 (en) 1995-04-19
PT99064A (pt) 1992-08-31
IE66042B1 (en) 1995-12-13
FI931370A0 (fi) 1993-03-26
MX9101274A (es) 1992-05-04
DE69109125T2 (de) 1995-09-28

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