FI925520A0 - Nya trans-cyklopentanylpurinanaloger, vilka aer anvaendbara som immundaempare - Google Patents

Nya trans-cyklopentanylpurinanaloger, vilka aer anvaendbara som immundaempare

Info

Publication number
FI925520A0
FI925520A0 FI925520A FI925520A FI925520A0 FI 925520 A0 FI925520 A0 FI 925520A0 FI 925520 A FI925520 A FI 925520A FI 925520 A FI925520 A FI 925520A FI 925520 A0 FI925520 A0 FI 925520A0
Authority
FI
Finland
Prior art keywords
trans
immundaempare
cyclopentanylpurinanaloger
nya
hydrogen
Prior art date
Application number
FI925520A
Other languages
English (en)
Other versions
FI925520A (fi
FI109026B (fi
Inventor
David Roger Borcherding
Carl Keith Edwards Iii
Ronald Eugene Esser
Douglas Leon Cole
Original Assignee
Marion Merrell Dow Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc
Publication of FI925520A0 publication Critical patent/FI925520A0/fi
Publication of FI925520A publication Critical patent/FI925520A/fi
Application granted granted Critical
Publication of FI109026B publication Critical patent/FI109026B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
FI925520A 1991-12-06 1992-12-04 Menetelmä uusien immuunivastetta heikentävien trans-syklopentanyylipuriinianalogien valmistamiseksi FI109026B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80415391A 1991-12-06 1991-12-06
US80415391 1991-12-06
US96560192A 1992-11-02 1992-11-02
US96560192 1992-11-02

Publications (3)

Publication Number Publication Date
FI925520A0 true FI925520A0 (fi) 1992-12-04
FI925520A FI925520A (fi) 1993-06-07
FI109026B FI109026B (fi) 2002-05-15

Family

ID=27122672

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925520A FI109026B (fi) 1991-12-06 1992-12-04 Menetelmä uusien immuunivastetta heikentävien trans-syklopentanyylipuriinianalogien valmistamiseksi

Country Status (17)

Country Link
EP (1) EP0545413B1 (fi)
JP (1) JP3264289B2 (fi)
KR (1) KR100251996B1 (fi)
AT (1) ATE194618T1 (fi)
AU (1) AU658698B2 (fi)
CA (1) CA2084222C (fi)
DE (1) DE69231242T2 (fi)
DK (1) DK0545413T3 (fi)
ES (1) ES2149163T3 (fi)
FI (1) FI109026B (fi)
GR (1) GR3034586T3 (fi)
HU (2) HU217077B (fi)
IL (1) IL103962A (fi)
MX (1) MX9206963A (fi)
NO (1) NO305207B1 (fi)
NZ (1) NZ245342A (fi)
PT (1) PT545413E (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100337720B1 (ko) 1993-06-21 2002-11-02 메렐 파마슈티칼스 인크. 신규카보사이클릭뉴클레오사이드화합물
AU698419B2 (en) * 1996-07-03 1998-10-29 Dainippon Sumitomo Pharma Co., Ltd. A novel purine derivative
US6479487B1 (en) * 1998-02-26 2002-11-12 Aventis Pharmaceuticals Inc. 6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
US6413974B1 (en) 1998-02-26 2002-07-02 Aventis Pharmaceuticals Inc. 6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
FR2793794B1 (fr) * 1999-05-21 2001-07-27 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
US6861524B2 (en) 2000-10-31 2005-03-01 Aventis Pharmaceuticals Inc. Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038479A (en) * 1969-11-17 1977-07-26 Burroughs Wellcome Co. Amino purine derivatives
US4076711A (en) * 1976-04-05 1978-02-28 Schering Corporation Triazolo [4,5-d]-pyrimidines
CA2001715C (en) * 1988-11-14 1999-12-28 Muzammil M. Mansuri Carbocyclic nucleosides and nucleotides
DE69116750T2 (de) * 1990-07-04 1996-11-14 Merrell Dow Pharma 9-Purinyl-Phosphonsäurederivate
CA2051012C (en) * 1990-09-14 2002-04-02 David R. Borcherding Carbocyclic adenosine analogs useful as immunosupressants

Also Published As

Publication number Publication date
HU217077B (hu) 1999-11-29
IL103962A (en) 1997-01-10
IL103962A0 (en) 1993-05-13
NO924691D0 (no) 1992-12-04
NZ245342A (en) 1995-10-26
HUT62896A (en) 1993-06-28
DE69231242D1 (de) 2000-08-17
CA2084222C (en) 2004-04-06
ES2149163T3 (es) 2000-11-01
MX9206963A (es) 1993-06-01
FI925520A (fi) 1993-06-07
DK0545413T3 (da) 2000-10-09
HU9203858D0 (en) 1993-03-29
EP0545413B1 (en) 2000-07-12
JP3264289B2 (ja) 2002-03-11
ATE194618T1 (de) 2000-07-15
JPH0656835A (ja) 1994-03-01
DE69231242T2 (de) 2000-12-21
PT545413E (pt) 2000-10-31
FI109026B (fi) 2002-05-15
AU2975292A (en) 1993-06-10
EP0545413A1 (en) 1993-06-09
GR3034586T3 (en) 2001-01-31
CA2084222A1 (en) 1993-06-07
NO924691L (no) 1993-06-07
NO305207B1 (no) 1999-04-19
KR100251996B1 (ko) 2000-09-01
AU658698B2 (en) 1995-04-27

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Legal Events

Date Code Title Description
MA Patent expired