DK0475413T3 - Carbocycliske nukleosidanaloge, der kan anvendes som immunsuppressorer - Google Patents

Carbocycliske nukleosidanaloge, der kan anvendes som immunsuppressorer

Info

Publication number
DK0475413T3
DK0475413T3 DK91115487.0T DK91115487T DK0475413T3 DK 0475413 T3 DK0475413 T3 DK 0475413T3 DK 91115487 T DK91115487 T DK 91115487T DK 0475413 T3 DK0475413 T3 DK 0475413T3
Authority
DK
Denmark
Prior art keywords
immunosuppressors
nucleoside analogues
carbocyclic nucleoside
halogen
hydrogen
Prior art date
Application number
DK91115487.0T
Other languages
English (en)
Inventor
David R Borcherding
Ronald E Esser
Iii Carl K Edwards
Douglas L Cole
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0475413T3 publication Critical patent/DK0475413T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK91115487.0T 1990-09-14 1991-09-12 Carbocycliske nukleosidanaloge, der kan anvendes som immunsuppressorer DK0475413T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58226590A 1990-09-14 1990-09-14
US74817391A 1991-08-23 1991-08-23

Publications (1)

Publication Number Publication Date
DK0475413T3 true DK0475413T3 (da) 1996-07-15

Family

ID=27078521

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91115487.0T DK0475413T3 (da) 1990-09-14 1991-09-12 Carbocycliske nukleosidanaloge, der kan anvendes som immunsuppressorer

Country Status (10)

Country Link
EP (1) EP0475413B1 (da)
JP (1) JPH0543578A (da)
KR (1) KR0175313B1 (da)
AT (1) ATE139444T1 (da)
AU (1) AU642526B2 (da)
DE (1) DE69120357T2 (da)
DK (1) DK0475413T3 (da)
ES (1) ES2090193T3 (da)
GR (1) GR3020794T3 (da)
IE (1) IE74172B1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0521463A3 (en) * 1991-07-04 1993-04-14 Hoechst Aktiengesellschaft Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents
ES2103131T3 (es) 1993-06-21 1997-08-16 Merrell Pharma Inc Nuevos agentes de nucleosido carbociclico utiles como inhibidores selectivos de citoquinas proinflamatorias.
US6395733B1 (en) 1995-06-07 2002-05-28 Pfizer Inc Heterocyclic ring-fused pyrimidine derivatives
WO2005019218A1 (ja) * 2003-08-26 2005-03-03 Teijin Pharma Limited ピロロピリミジンチオン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2001715C (en) * 1988-11-14 1999-12-28 Muzammil M. Mansuri Carbocyclic nucleosides and nucleotides
CA2051012C (en) * 1990-09-14 2002-04-02 David R. Borcherding Carbocyclic adenosine analogs useful as immunosupressants

Also Published As

Publication number Publication date
JPH0543578A (ja) 1993-02-23
EP0475413A2 (en) 1992-03-18
KR0175313B1 (ko) 1999-02-18
AU642526B2 (en) 1993-10-21
IE74172B1 (en) 1997-07-02
DE69120357T2 (de) 1996-11-28
ATE139444T1 (de) 1996-07-15
ES2090193T3 (es) 1996-10-16
KR920005985A (ko) 1992-04-27
GR3020794T3 (en) 1996-11-30
EP0475413B1 (en) 1996-06-19
AU8372891A (en) 1992-03-19
DE69120357D1 (de) 1996-07-25
IE913248A1 (en) 1992-02-25
EP0475413A3 (en) 1992-11-04

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