ATE139444T1 - Carbocyklische nukleosidanaloge als immunsuppressoren - Google Patents

Carbocyklische nukleosidanaloge als immunsuppressoren

Info

Publication number
ATE139444T1
ATE139444T1 AT91115487T AT91115487T ATE139444T1 AT E139444 T1 ATE139444 T1 AT E139444T1 AT 91115487 T AT91115487 T AT 91115487T AT 91115487 T AT91115487 T AT 91115487T AT E139444 T1 ATE139444 T1 AT E139444T1
Authority
AT
Austria
Prior art keywords
immunosupressors
nucleoside analogues
carbocyclic nucleoside
halogen
hydrogen
Prior art date
Application number
AT91115487T
Other languages
English (en)
Inventor
David R Borcherding
Ronald E Esser
Iii Carl K Edwards
Douglas L Cole
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of ATE139444T1 publication Critical patent/ATE139444T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91115487T 1990-09-14 1991-09-12 Carbocyklische nukleosidanaloge als immunsuppressoren ATE139444T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58226590A 1990-09-14 1990-09-14
US74817391A 1991-08-23 1991-08-23

Publications (1)

Publication Number Publication Date
ATE139444T1 true ATE139444T1 (de) 1996-07-15

Family

ID=27078521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91115487T ATE139444T1 (de) 1990-09-14 1991-09-12 Carbocyklische nukleosidanaloge als immunsuppressoren

Country Status (10)

Country Link
EP (1) EP0475413B1 (de)
JP (1) JPH0543578A (de)
KR (1) KR0175313B1 (de)
AT (1) ATE139444T1 (de)
AU (1) AU642526B2 (de)
DE (1) DE69120357T2 (de)
DK (1) DK0475413T3 (de)
ES (1) ES2090193T3 (de)
GR (1) GR3020794T3 (de)
IE (1) IE74172B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0521463A3 (en) * 1991-07-04 1993-04-14 Hoechst Aktiengesellschaft Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents
CA2165779C (en) 1993-06-21 1998-06-16 Carl K. Edwards, Iii Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines
US6395733B1 (en) 1995-06-07 2002-05-28 Pfizer Inc Heterocyclic ring-fused pyrimidine derivatives
CA2536887C (en) * 2003-08-26 2012-03-06 Teijin Pharma Limited Pyrrolopyrimidinone derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2001715C (en) * 1988-11-14 1999-12-28 Muzammil M. Mansuri Carbocyclic nucleosides and nucleotides
CA2051012C (en) * 1990-09-14 2002-04-02 David R. Borcherding Carbocyclic adenosine analogs useful as immunosupressants

Also Published As

Publication number Publication date
GR3020794T3 (en) 1996-11-30
AU642526B2 (en) 1993-10-21
EP0475413B1 (de) 1996-06-19
JPH0543578A (ja) 1993-02-23
ES2090193T3 (es) 1996-10-16
KR920005985A (ko) 1992-04-27
EP0475413A3 (en) 1992-11-04
IE74172B1 (en) 1997-07-02
DE69120357T2 (de) 1996-11-28
AU8372891A (en) 1992-03-19
DE69120357D1 (de) 1996-07-25
EP0475413A2 (de) 1992-03-18
DK0475413T3 (da) 1996-07-15
IE913248A1 (en) 1992-02-25
KR0175313B1 (ko) 1999-02-18

Similar Documents

Publication Publication Date Title
FI931370A0 (fi) Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring
ATE110382T1 (de) Oxetanocin.
CA2051012A1 (en) Carbocyclic adenosine analogs useful as immunosupressants
ES2157992T3 (es) Alcoxi-alquil-carbamatos de imidazo(1,2-a)piridinas.
ATE139444T1 (de) Carbocyklische nukleosidanaloge als immunsuppressoren
DE69127303D1 (de) Substituierte Triazolopyridazine
ES2103131T3 (es) Nuevos agentes de nucleosido carbociclico utiles como inhibidores selectivos de citoquinas proinflamatorias.
ATE194618T1 (de) Als immunosuppressiva nützliche trans- cyclopentanylpurinanaloge
EA199900684A1 (ru) Производные иминоазаантрациклинона для лечения амилоидоза
DE3464609D1 (en) Spiro(benzofuran-azalkanes), a method for their preparation and their use as medicaments
IT1251202B (it) 6-amminochinoloni, sintesi ed impiego come antibatterici
FR2395995A1 (fr) Nouveaux derives d'a-vinylaminoacides, leur preparation et leur utilisation comme inhibiteurs de la decarboxylase des aminoacides aromatiques
FR2398736A1 (fr) Derives a-halogenomethyles d'aminoacides, leur procede de preparation et leur utilisation comme antiallergiques
FR2397836A1 (fr) Derives de l'oxo-1-dihydro-1,2-isoquinoleine utilises comme agents anti-inflammatoires analgesiques forts
BE898856A (fr) Analogues de mitomycine
SE9603726D0 (sv) Novel compounds
ES2133573T3 (es) Analogos antiviricos de difluoro estatone.
FR2394518A1 (fr) Diesters dihydroxyles derivant de 2,2,4,4-tetraalkylbutane-1,3-diols et compositions de couchage les contenant

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee