DE69120357D1 - Carbocyklische Nukleosidanaloge als Immunsuppressoren - Google Patents

Carbocyklische Nukleosidanaloge als Immunsuppressoren

Info

Publication number
DE69120357D1
DE69120357D1 DE69120357T DE69120357T DE69120357D1 DE 69120357 D1 DE69120357 D1 DE 69120357D1 DE 69120357 T DE69120357 T DE 69120357T DE 69120357 T DE69120357 T DE 69120357T DE 69120357 D1 DE69120357 D1 DE 69120357D1
Authority
DE
Germany
Prior art keywords
immunosuppressors
nucleoside analogues
carbocyclic nucleoside
halogen
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69120357T
Other languages
English (en)
Other versions
DE69120357T2 (de
Inventor
David R Borcherding
Ronald E Esser
Iii Carl K Edwards
Douglas L Cole
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DE69120357D1 publication Critical patent/DE69120357D1/de
Publication of DE69120357T2 publication Critical patent/DE69120357T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69120357T 1990-09-14 1991-09-12 Carbocyklische Nukleosidanaloge als Immunsuppressoren Expired - Fee Related DE69120357T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58226590A 1990-09-14 1990-09-14
US74817391A 1991-08-23 1991-08-23

Publications (2)

Publication Number Publication Date
DE69120357D1 true DE69120357D1 (de) 1996-07-25
DE69120357T2 DE69120357T2 (de) 1996-11-28

Family

ID=27078521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69120357T Expired - Fee Related DE69120357T2 (de) 1990-09-14 1991-09-12 Carbocyklische Nukleosidanaloge als Immunsuppressoren

Country Status (10)

Country Link
EP (1) EP0475413B1 (de)
JP (1) JPH0543578A (de)
KR (1) KR0175313B1 (de)
AT (1) ATE139444T1 (de)
AU (1) AU642526B2 (de)
DE (1) DE69120357T2 (de)
DK (1) DK0475413T3 (de)
ES (1) ES2090193T3 (de)
GR (1) GR3020794T3 (de)
IE (1) IE74172B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0521463A3 (en) * 1991-07-04 1993-04-14 Hoechst Aktiengesellschaft Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents
CN1041631C (zh) 1993-06-21 1999-01-13 默里尔药物公司 用作炎症前细胞因子选择性抑制剂的新的碳环核苷药物
US6395733B1 (en) 1995-06-07 2002-05-28 Pfizer Inc Heterocyclic ring-fused pyrimidine derivatives
TW200509938A (en) * 2003-08-26 2005-03-16 Teijin Pharma Ltd Pyrrolopyrimidine thion derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2001715C (en) * 1988-11-14 1999-12-28 Muzammil M. Mansuri Carbocyclic nucleosides and nucleotides
CA2051012C (en) * 1990-09-14 2002-04-02 David R. Borcherding Carbocyclic adenosine analogs useful as immunosupressants

Also Published As

Publication number Publication date
AU8372891A (en) 1992-03-19
GR3020794T3 (en) 1996-11-30
ES2090193T3 (es) 1996-10-16
IE74172B1 (en) 1997-07-02
IE913248A1 (en) 1992-02-25
ATE139444T1 (de) 1996-07-15
KR920005985A (ko) 1992-04-27
JPH0543578A (ja) 1993-02-23
DE69120357T2 (de) 1996-11-28
KR0175313B1 (ko) 1999-02-18
DK0475413T3 (da) 1996-07-15
EP0475413A3 (en) 1992-11-04
EP0475413B1 (de) 1996-06-19
EP0475413A2 (de) 1992-03-18
AU642526B2 (en) 1993-10-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee