HU9203858D0 - New trans-cyclopentanyl-purine analogues having immuno suppressing effect - Google Patents

New trans-cyclopentanyl-purine analogues having immuno suppressing effect

Info

Publication number
HU9203858D0
HU9203858D0 HU9203858A HU385892A HU9203858D0 HU 9203858 D0 HU9203858 D0 HU 9203858D0 HU 9203858 A HU9203858 A HU 9203858A HU 385892 A HU385892 A HU 385892A HU 9203858 D0 HU9203858 D0 HU 9203858D0
Authority
HU
Hungary
Prior art keywords
cyclopentanyl
suppressing effect
purine analogues
hydrogen
trans
Prior art date
Application number
HU9203858A
Other languages
English (en)
Inventor
David Roger Borcherding
Carl Keith Edwars
Ronald Eugene Esser
Douglas Leon Cole
Original Assignee
Marion Merrell Dow Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc
Publication of HU9203858D0 publication Critical patent/HU9203858D0/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9203858A 1991-12-06 1992-12-04 New trans-cyclopentanyl-purine analogues having immuno suppressing effect HU9203858D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80415391A 1991-12-06 1991-12-06
US96560192A 1992-11-02 1992-11-02

Publications (1)

Publication Number Publication Date
HU9203858D0 true HU9203858D0 (en) 1993-03-29

Family

ID=27122672

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9203858A HU9203858D0 (en) 1991-12-06 1992-12-04 New trans-cyclopentanyl-purine analogues having immuno suppressing effect
HU9203858A HU217077B (hu) 1991-12-06 1992-12-04 Eljárás immunoszupresszáns hatású transz-ciklopentanil-purin-analógok és ezeket tartalmazó gyógyszerkészítmények előállítására

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9203858A HU217077B (hu) 1991-12-06 1992-12-04 Eljárás immunoszupresszáns hatású transz-ciklopentanil-purin-analógok és ezeket tartalmazó gyógyszerkészítmények előállítására

Country Status (17)

Country Link
EP (1) EP0545413B1 (hu)
JP (1) JP3264289B2 (hu)
KR (1) KR100251996B1 (hu)
AT (1) ATE194618T1 (hu)
AU (1) AU658698B2 (hu)
CA (1) CA2084222C (hu)
DE (1) DE69231242T2 (hu)
DK (1) DK0545413T3 (hu)
ES (1) ES2149163T3 (hu)
FI (1) FI109026B (hu)
GR (1) GR3034586T3 (hu)
HU (2) HU9203858D0 (hu)
IL (1) IL103962A (hu)
MX (1) MX9206963A (hu)
NO (1) NO305207B1 (hu)
NZ (1) NZ245342A (hu)
PT (1) PT545413E (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT73412A (en) 1993-06-21 1996-07-29 Merrell Pharma Inc Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines
ES2232871T3 (es) * 1996-07-03 2005-06-01 Sumitomo Pharmaceuticals Company, Limited Nuevos derivados de purina.
US6413974B1 (en) 1998-02-26 2002-07-02 Aventis Pharmaceuticals Inc. 6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
US6479487B1 (en) * 1998-02-26 2002-11-12 Aventis Pharmaceuticals Inc. 6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
FR2793794B1 (fr) * 1999-05-21 2001-07-27 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
US6861524B2 (en) 2000-10-31 2005-03-01 Aventis Pharmaceuticals Inc. Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038479A (en) * 1969-11-17 1977-07-26 Burroughs Wellcome Co. Amino purine derivatives
US4076711A (en) * 1976-04-05 1978-02-28 Schering Corporation Triazolo [4,5-d]-pyrimidines
CA2001715C (en) * 1988-11-14 1999-12-28 Muzammil M. Mansuri Carbocyclic nucleosides and nucleotides
ES2085446T3 (es) * 1990-07-04 1996-06-01 Merrell Pharma Inc Derivados de acido 9-purinil fosfonico.
AU647822B2 (en) * 1990-09-14 1994-03-31 Marion Merrell Dow Inc. Novel carbocyclic adenosine analogs useful as immunosuppressants

Also Published As

Publication number Publication date
NO924691D0 (no) 1992-12-04
PT545413E (pt) 2000-10-31
KR100251996B1 (ko) 2000-09-01
FI925520A (fi) 1993-06-07
HUT62896A (en) 1993-06-28
FI925520A0 (fi) 1992-12-04
ES2149163T3 (es) 2000-11-01
NO924691L (no) 1993-06-07
CA2084222A1 (en) 1993-06-07
GR3034586T3 (en) 2001-01-31
IL103962A0 (en) 1993-05-13
HU217077B (hu) 1999-11-29
DE69231242T2 (de) 2000-12-21
FI109026B (fi) 2002-05-15
JP3264289B2 (ja) 2002-03-11
EP0545413A1 (en) 1993-06-09
MX9206963A (es) 1993-06-01
DK0545413T3 (da) 2000-10-09
NZ245342A (en) 1995-10-26
EP0545413B1 (en) 2000-07-12
AU658698B2 (en) 1995-04-27
NO305207B1 (no) 1999-04-19
ATE194618T1 (de) 2000-07-15
JPH0656835A (ja) 1994-03-01
IL103962A (en) 1997-01-10
CA2084222C (en) 2004-04-06
DE69231242D1 (de) 2000-08-17
AU2975292A (en) 1993-06-10

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