FI894045A - Menetelmä terapeuttisesti aktiivisen 10-atsaspiro-9-fluori-2,3-dihydro-3-metyyli-7-okso-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihappojohdannaisen valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisen 10-atsaspiro-9-fluori-2,3-dihydro-3-metyyli-7-okso-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihappojohdannaisen valmistamiseksi Download PDF

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Publication number
FI894045A
FI894045A FI894045A FI894045A FI894045A FI 894045 A FI894045 A FI 894045A FI 894045 A FI894045 A FI 894045A FI 894045 A FI894045 A FI 894045A FI 894045 A FI894045 A FI 894045A
Authority
FI
Finland
Prior art keywords
azaspiro
benzoxazine
pyrido
dihydro
oxo
Prior art date
Application number
FI894045A
Other languages
English (en)
Swedish (sv)
Other versions
FI92703B (fi
FI894045A0 (fi
FI92703C (fi
Inventor
Isao Hayakawa
Shohgo Atarashi
Masazumi Imamura
Youichi Kimura
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of FI894045A0 publication Critical patent/FI894045A0/fi
Publication of FI894045A publication Critical patent/FI894045A/fi
Priority to FI934016A priority Critical patent/FI101536B1/fi
Publication of FI92703B publication Critical patent/FI92703B/fi
Application granted granted Critical
Publication of FI92703C publication Critical patent/FI92703C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Dental Preparations (AREA)
  • Luminescent Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI894045A 1988-08-31 1989-08-29 Menetelmä terapeuttisesti aktiivisen 10-atsaspiro-9-fluori-2,3-dihydro-3-metyyli-7-okso-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihappojohdannaisen valmistamiseksi FI92703C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI934016A FI101536B1 (fi) 1988-08-31 1993-09-14 Menetelmä terapeuttisesti käyttökelpoisten spirosubstituentin sisältävien kinoliini- tai naftyridiinikarboksyylihappojohdannaisten valmistamiseksi

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP21763888 1988-08-31
JP21763888 1988-08-31
JP23131888 1988-09-14
JP23131888 1988-09-14
JP29698588 1988-11-24
JP29698588 1988-11-24
JP15631689 1989-06-19
JP15631689 1989-06-19

Publications (4)

Publication Number Publication Date
FI894045A0 FI894045A0 (fi) 1989-08-29
FI894045A true FI894045A (fi) 1990-03-01
FI92703B FI92703B (fi) 1994-09-15
FI92703C FI92703C (fi) 1994-12-27

Family

ID=27473404

Family Applications (1)

Application Number Title Priority Date Filing Date
FI894045A FI92703C (fi) 1988-08-31 1989-08-29 Menetelmä terapeuttisesti aktiivisen 10-atsaspiro-9-fluori-2,3-dihydro-3-metyyli-7-okso-7H-pyrido/1,2,3-de//1,4/bentsoksatsiini-6-karboksyylihappojohdannaisen valmistamiseksi

Country Status (20)

Country Link
US (1) US5508428A (fi)
EP (2) EP0529688B1 (fi)
KR (2) KR0148688B1 (fi)
CN (1) CN1036193C (fi)
AT (1) ATE160141T1 (fi)
AU (1) AU619891B2 (fi)
CA (1) CA1336090C (fi)
DE (2) DE68928447T2 (fi)
DK (1) DK174689B1 (fi)
ES (2) ES2061845T3 (fi)
FI (1) FI92703C (fi)
HK (1) HK1003000A1 (fi)
IE (2) IE63492B1 (fi)
IL (1) IL91474A (fi)
IN (1) IN170262B (fi)
MY (1) MY104652A (fi)
NO (1) NO177638C (fi)
NZ (1) NZ230484A (fi)
PH (1) PH31278A (fi)
PT (1) PT91602B (fi)

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US5137892A (en) * 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
ATE184603T1 (de) * 1991-06-19 1999-10-15 Pfizer Azaspirochinolone als antibakterielle wirkstoffe
US5276041A (en) * 1991-11-08 1994-01-04 Kaken Pharmaceutical Co., Ltd. Oxime derivatives
EP0550016A1 (en) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same
KR960011370B1 (ko) * 1991-12-31 1996-08-22 재단법인 한국화학연구소 스피로알킬아민 유도체와 그의 제조방법
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
EP0688772B1 (en) * 1994-06-16 1999-05-06 LG Chemical Limited Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation
EP0829473B1 (en) 1995-05-26 2002-08-07 Daiichi Pharmaceutical Co., Ltd. Processes for preparing cyclic compounds
BG62359B1 (bg) * 1995-07-13 1999-09-30 Anormed N,n-диетил-8,8-дипропил-2-азаспиро[4,5]декан-2-пропанаминдималеат
TW519542B (en) * 1996-09-27 2003-02-01 Daiichi Seiyaku Co Bicyclic amine derivative
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
MA24500A1 (fr) * 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
JP3280388B2 (ja) 1997-06-26 2002-05-13 ドング ホワ ファーマシューチカル インダストリアル カンパニー，リミテッド キノロンカルボン酸誘導体
DE19751948A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
EP1262477B1 (en) * 2000-02-09 2008-09-03 Daiichi Sankyo Company, Limited Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient
AU2001276750A1 (en) * 2000-08-08 2002-02-25 Daiichi Pharmaceutical Co., Ltd. Processes for preparation of bicyclic compounds and intermediates therefor
JP4108311B2 (ja) * 2001-10-02 2008-06-25 ダイセル化学工業株式会社 １−アシル−１−シクロプロパンカルボン酸エステル誘導体の製造法
JP2003171354A (ja) 2001-12-06 2003-06-20 Daicel Chem Ind Ltd 光学活性アミン化合物又はその塩の製造方法
WO2005026145A2 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
US7977346B2 (en) 2006-01-17 2011-07-12 Guoqing Paul Chen Spiro compounds and methods of use
WO2009089235A1 (en) * 2008-01-07 2009-07-16 Janssen Pharmaceutica N.V. Preparation of sulfamide derivatives
CN103562208B (zh) 2011-03-15 2016-08-31 默沙东公司 三环促旋酶抑制剂
WO2012150208A1 (de) 2011-05-04 2012-11-08 Bayer Cropscience Ag Verwendung von substituierten benzylalkoholestern der cyclopropancarbonsäure zur bekämpfung von insektizid-resistenten insekten
WO2012150221A2 (de) 2011-05-04 2012-11-08 Bayer Cropscience Ag Neue halogenierte benzylalkoholester der cyclopropancarbonsäure als schädlingsbekämpfungsmittel
CN103073481A (zh) * 2013-02-06 2013-05-01 上海药明康德新药开发有限公司 一种4-氮杂螺[2.4]庚烷盐酸盐的制备方法
WO2019027860A1 (en) * 2017-08-01 2019-02-07 Boehringer Ingelheim International Gmbh INTERMEDIATE COMPOUNDS AND METHODS

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Also Published As

Publication number Publication date
KR900003152A (ko) 1990-03-23
AU619891B2 (en) 1992-02-06
KR0148719B1 (en) 1998-08-17
MY104652A (en) 1994-05-31
IE892785L (en) 1990-02-28
NO177638C (no) 1995-10-25
DK426289A (da) 1990-03-01
CN1036193C (zh) 1997-10-22
CN1100095A (zh) 1995-03-15
PT91602A (pt) 1990-03-08
EP0529688A3 (en) 1993-03-10
FI92703B (fi) 1994-09-15
NO177638B (no) 1995-07-17
FI894045A0 (fi) 1989-08-29
PT91602B (pt) 1995-05-31
EP0529688B1 (en) 1997-11-12
NZ230484A (en) 1991-06-25
DE68910441D1 (de) 1993-12-09
DK426289D0 (da) 1989-08-30
HK1003000A1 (en) 1998-09-30
NO893453L (no) 1990-03-01
IL91474A0 (en) 1990-04-29
DE68928447T2 (de) 1998-06-18
DE68910441T2 (de) 1994-03-03
ES2061845T3 (es) 1994-12-16
CA1336090C (en) 1995-06-27
IE930570L (en) 1990-02-28
DK174689B1 (da) 2003-09-15
DE68928447D1 (de) 1997-12-18
EP0529688A2 (en) 1993-03-03
ES2111029T3 (es) 1998-03-01
NO893453D0 (no) 1989-08-29
US5508428A (en) 1996-04-16
IE82128B1 (en) 2002-02-20
FI92703C (fi) 1994-12-27
AU4100689A (en) 1990-03-08
IN170262B (fi) 1992-03-07
PH31278A (en) 1998-07-06
IL91474A (en) 1994-05-30
ATE160141T1 (de) 1997-11-15
KR0148688B1 (ko) 1998-08-17
EP0357047B1 (en) 1993-11-03
EP0357047A1 (en) 1990-03-07
IE63492B1 (en) 1995-05-03

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: DAIICHI PHARMACEUTICAL CO. LTD.

BB Publication of examined application
FG Patent granted

Owner name: DAIICHI PHARMACEUTICAL CO., LTD.