FI893535A - Nytt foerfarande. - Google Patents

Nytt foerfarande. Download PDF

Info

Publication number
FI893535A
FI893535A FI893535A FI893535A FI893535A FI 893535 A FI893535 A FI 893535A FI 893535 A FI893535 A FI 893535A FI 893535 A FI893535 A FI 893535A FI 893535 A FI893535 A FI 893535A
Authority
FI
Finland
Prior art keywords
acyloxymethyl
hydroxymethyl
hydrogen
converting
group
Prior art date
Application number
FI893535A
Other languages
English (en)
Finnish (fi)
Other versions
FI893535A0 (fi
Inventor
Trevor John Grinter
Peter Markham Kincey
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of FI893535A0 publication Critical patent/FI893535A0/fi
Publication of FI893535A publication Critical patent/FI893535A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/14—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with two methyl radicals in positions 1 and 3 and two methyl radicals in positions 7, 8, or 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Mechanical Operated Clutches (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
FI893535A 1988-07-23 1989-07-21 Nytt foerfarande. FI893535A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817607A GB8817607D0 (en) 1988-07-23 1988-07-23 Novel process

Publications (2)

Publication Number Publication Date
FI893535A0 FI893535A0 (fi) 1989-07-21
FI893535A true FI893535A (fi) 1990-01-24

Family

ID=10641009

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893535A FI893535A (fi) 1988-07-23 1989-07-21 Nytt foerfarande.

Country Status (19)

Country Link
US (1) US5017701A (hu)
EP (1) EP0352953B1 (hu)
JP (1) JP2856773B2 (hu)
KR (1) KR0137468B1 (hu)
AT (1) ATE198479T1 (hu)
AU (1) AU623667B2 (hu)
DE (1) DE68929277T2 (hu)
DK (1) DK171991B1 (hu)
ES (1) ES2153343T3 (hu)
FI (1) FI893535A (hu)
GB (1) GB8817607D0 (hu)
HK (1) HK1012355A1 (hu)
HU (1) HU204829B (hu)
MA (1) MA21601A1 (hu)
NO (1) NO169008C (hu)
NZ (1) NZ230026A (hu)
PL (1) PL161207B1 (hu)
PT (1) PT91247B (hu)
ZA (1) ZA895567B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
US5175288A (en) * 1987-08-01 1992-12-29 Beecham Group P.L.C. Process for preparing purine derivatives and intermediates thereof
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process
DE4020481A1 (de) * 1990-06-27 1992-01-02 Hoechst Ag Verfahren zur herstellung von substituierten acyclischen nukleosiden und dabei auftretende zwischenprodukte
CA2076886C (en) * 1991-11-22 2002-06-11 Masami Igi Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
US5874578A (en) * 1992-07-13 1999-02-23 Bristol-Myers Squibb Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process
GB9407698D0 (en) * 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
JP3241994B2 (ja) * 1995-07-03 2001-12-25 株式会社荏原製作所 水中モータ及び防水コネクタ
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
ES2138535B1 (es) * 1996-07-20 2000-11-16 Smithkline Beecham Plc Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir.
GB9615275D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
EP0827960A1 (en) * 1996-09-10 1998-03-11 Ajinomoto Co., Inc. Process for producing purine derivatives
GB9807114D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
EP1352910A1 (en) * 2002-04-10 2003-10-15 Grünenthal GmbH New analogs of nitrobenzylthioinosine
WO2004018470A2 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
CA2541989C (en) * 2003-10-24 2013-10-01 Exelixis, Inc. P70s6 kinase modulators and method of use
TW200613304A (en) * 2004-05-18 2006-05-01 Teva Pharma Drying process for preparing crystalline solid famciclovir
DE602004009166T2 (de) * 2004-06-29 2008-08-21 Grünenthal GmbH Neue Analoga von Nitrobenzylthioinosin
KR100618232B1 (ko) * 2004-09-22 2006-09-04 한미약품 주식회사 팜시클로버의 제조방법
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347185A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids
US4347187A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein
AU577303B2 (en) * 1983-08-18 1988-09-22 Novartis International Pharmaceutical Ltd 9-substituted-2-amino purines
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4845084A (en) * 1984-01-26 1989-07-04 Merck & Co., Inc. Phosphate derivatives of substituted butyl guanines, antiviral compositions containing them, and methods of treating viral infections with them
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
ES2098219T3 (es) * 1987-08-01 1997-05-01 Beecham Group Plc Compuestos de purina y su preparacion.
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process

Also Published As

Publication number Publication date
JPH0259583A (ja) 1990-02-28
NO892998D0 (no) 1989-07-21
KR0137468B1 (ko) 1998-06-01
NO169008B (no) 1992-01-20
JP2856773B2 (ja) 1999-02-10
KR910002856A (ko) 1991-02-26
DK171991B1 (da) 1997-09-08
NZ230026A (en) 1992-11-25
DE68929277T2 (de) 2001-08-23
EP0352953A3 (en) 1991-10-23
EP0352953B1 (en) 2001-01-03
DK362689D0 (da) 1989-07-21
ZA895567B (en) 1990-07-25
ES2153343T3 (es) 2001-03-01
EP0352953A2 (en) 1990-01-31
ATE198479T1 (de) 2001-01-15
HUT50820A (en) 1990-03-28
PL161207B1 (en) 1993-06-30
DK362689A (da) 1990-01-24
DE68929277D1 (de) 2001-02-08
PT91247B (pt) 1995-05-04
NO169008C (no) 1992-04-29
PT91247A (pt) 1990-02-08
NO892998L (no) 1990-01-24
HK1012355A1 (en) 1999-07-30
FI893535A0 (fi) 1989-07-21
US5017701A (en) 1991-05-21
AU623667B2 (en) 1992-05-21
GB8817607D0 (en) 1988-09-01
HU204829B (en) 1992-02-28
AU3882289A (en) 1990-01-25
MA21601A1 (fr) 1990-04-01

Similar Documents

Publication Publication Date Title
FI893535A0 (fi) Nytt foerfarande.
HUT59675A (en) Process for producing chloro-thiazol derivatives
HUT47128A (en) Process for producing oxetanocins and pharmaceutical compositions comprising such compounds
EP0266182A3 (en) Gamma-lactonecarboxylic acid derivatives and their production
ES2056150T3 (es) Derivados del acido dietilentriamino-pentaacetico.
PL281368A1 (en) Method of obtaining novel purine derivatives
ES8307235A1 (es) Un procedimiento para la preparacion de ranitidina.
ES8607967A1 (es) Un procedimiento para la preparacion de nuevos derivados delacido tiazolilacetico
AU1880788A (en) A thiophene derivative and process for preparing the same
DE3261606D1 (en) Novel quinolinecarboxylic acid derivative, process for production thereof, and antibacterial agent containing said compound as active ingredient
HUT48260A (en) New process for producing 6-/d-/-alpha-/4-ethyl2,3-dioxo-1-piperazin-carboxamido/-phenyl-acetamido/-penicillanic acid
ES2060187T3 (es) Derivados de fenilglicina.
HUT43855A (en) Process for production of derivatives of cef-3-em-4-carbonic acid
SG43092A1 (en) Process for preparing 5-arylhydantoin
AU2181592A (en) Novel anti-viral compounds and processes for production of anti-viral compounds
JPS5557592A (en) Preparation of 3-carbamoyloxymethyl-2- or -3-cephem-4- carboxylic acid derivative

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: BEECHAM GROUP P.L.C.